Our project has several sub-components. The idea was to create a potentially economically viable production platform in Nicotiana benthamiana, testing various Arabidopsis thaliana promoters that respond to different stimuli. The production platform was to be ideally used to produce high levels of therapeutic products, with the appropriate post-translational modifications (PTMs) that makes using plants as a production system more favourable than bacteria. The therapeutic product that we tried to produce was an antagonist to thyroid stimulating hormone, with the aim that this would be able to treat hyperthyroid disorders such as Graves’ disease.
