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Our Story
NUDT_CHINA
MicroRNAs (miRNAs) have been proven to play important roles
on post-transcriptionalregulation of the gene expression by
direct base pairing to target sites within untranslated regions of
messenger RNAs.
However, the functions of most microRNAs remain to be
discovered. Our project attempts to develop a novel sponge for
miRNAs, which would knock down the abundance of target
miRNA in the cells.
Thus the sponge will be a miRNA inhibitor to be used to induce
miRNA loss-of-function phenotypes or other further applications
like small non-coding RNA-based diagnostic and therapeutic applications.
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