Team:Fudan China/Description

PROJECT

• DESCRIPTION

• TWO-SIGNAL SYSTEM

• MULTI-SIGNAL SYSTEM

• PARTS

MODELING

• INTEGRASE MODEL

• DIFFUSION MODEL

NOTEBOOK

• TIMELINE

• PROTOCOL

• INTERLAB

HP

• GENERAL

• INTEGRATED

TEAM

• TEAM MEMBER

• ATTRIBUTION

• COLLABORATION

UP

Background - The era of cellular memory

We have already known it since we were little that memory is related to our mind and is able to store and retrieve our pasts. Now, biological memory has been defined as a sustained cellular response to a transient stimulus¹. Cellular memory devices with cell or cell population have been developed in recent years. Some of them are based on transcriptional level, like toggle switch², the others are based on DNA level by employing various recombinases^{3, 4} or CRISPR^{5, 6}. Although existing devices may have different functioning mechanism, they all share the same ability to store the past and retrieve it whenever we need. Here, we will introduce some existing memory devices and the potential usage of cellular memory before introducing our project.