Team:UMaryland

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An Apeeling Solution
to Panama Disease

Projects

Saving the Cavendish banana

Outreach

Increasing access to synthetic biology for high schools

Parts
Modeling
Notebook

About Us

Learn more about UMaryland iGEM

Projects

From saving the Cavendish to expanding synthetic biology

An Appeling Solution

to save the Cavendish

Cas9 Mutant Screening

Screening for mutants using CRISPR/Cas9

Lab-in-a-box

Low cost DIY lab equipment

Metal Detection

Teaching synthetic biology using real world examples

Outreach

Reaching out to the community about synthetic biology

Knowing Panama Disease

Feedback, concerns, and feasiblity

Teaching the Next Generation

of synthetic biologists

Talking with the Community

about synthetic biology

About Us

UMaryland iGEM - Since 2014

Students

The next generation of scientists

Advisors

Guiding our efforts

Funding

Providing support for the team

Acknowl-
edgements

Those who helped us get here

Application

Contributing to the scientific community

Parts

Contributions to the Registry

Modeling

Applying engineering principles

Notebook

Follow our progress throughout our experience

An Apeeling Solution to Panama Disease

The banana is the most popular fruit in the world, with a whopping 160 million tons produced annually. In America, we think of the banana as a fruit, something we love but could live without. However, the same cannot be said for over 400 million people in poor countries. These individuals rely on bananas as their biggest, and sometimes, sole source of calories and nutrition. Terrifyingly enough, 7% of the world’s population could lose its sole source of food as the banana crop is being ravaged by a devastating pandemic: Panama disease.

Panama disease is caused by the fungus Fusarium oxysporum f. sp. Cubense race 4, which is deadly to the Cavendish banana. This fungus is able to first infect the roots of the plant, secreting different hydrolytic enzymes, and subsequently infect the xylem, blocking water and nutrient flow, leading to the death of the plant (Dong, Chunyu Li). Symptoms, however, are typically not visible until four months after infection, providing ample time for the fungus to spread without notice. (http://www.cabi.org/isc/datasheet/24621, http://www.promusa.org/Fusarium+wilt ). Additionally, the fungus remains in the soil in the form of spores for up to a decade, ready to infect the next set of plants. Therefore, there is a need to develop a method of protecting the Cavendish banana from Fusarium oxysporum and eliminating the fungus from the soil.