Team:BIT/MO1

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Model of Biosensor

Abstract:

As we all know, it is difficult to detect macromolecules with synthetic biological methods. The hardest problem is that it is difficult for macromolecules to enter the gene machine - cell body, that leads to follow-up work out of the question. For this problem, we propose a model that replaces the substance with another substance. Alpha-fetoprotein (AFP) is the substance that our project wants to detect, but alpha-fetoprotein is a macromolecule and is difficult to enter the body of engineering bacteria. So we use lysine, an easily detectable substance, to establish a mathematical relationship with our target concentration to detect the concentration of AFP indirectly.

If we can prove that the amount of lysine separated at different AFP concentrations is different, then we can prove that our project is feasible. At the same time the aim of our project is detection, if the lysine detection quantity has linear relationship with AFP concentration, then our project will have obvious advantages in detection.

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