Team:Linkoping Sweden/Description
Our Workplan
The overview of the project is summarized in figure 1 below. As can be seen in the figure, chaperones and conditions will be tested with various experiments, with the purpose to find the best setup for further detailed studies. The detailed studies will involve modeling with systems biology, where the modeling team will give suggestions on what the laboratory team shall do to achieve the desired task. The flow of data between the laboratory and the modeling team will eventually result in the final data, with is the optimized setup for the expression of our peptides.
Sources
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2. Alzheimer´s Disease International. Dementia statistics [Internet]. Cited 2017-06-27. Available from: https://www.alz.co.uk/research/statistics
3. Alzheimerfonden. Lexikon för Alzheimers sjukdom och andra demenssjukdomar [Internet]. Cited 2017-06-15. Available from: http://www.alzheimerfonden.se/om_demens/lexikon [in swedish]
4. Bloom GS. Amyloid-β and TauThe Trigger and Bullet in Alzheimer Disease Pathogenesis. JAMA Neurol. 2014;71(4):505-508. doi:10.1001/jamaneurol.2013.5847
