Team:NUS Singapore/Overview
Overview
Methodology
Methodology describes the modelling process we use to develop each of our models. Here you can find information about the equations and modelling workflow we use.
Kill switch for probiotics
The kill switch for probiotics is a successful proof of concept that demonstrates how our E2 chassis and modelling workflow can be used to make the engineering of customised killswitches for engineered probiotics easier. Using this model, our experimenters successfuly constructed the phosphate-temperature cascaded system with GFP reporter (BBa_K2447015). Here you can find the modelling workflow and modelling results that proves our design works!
Kill switch for BeeT
The kill switch for BeeT employs our E2 Chassis and automated circuit design included in our modelling workflow, to Wageningen iGEM2016's biocontainment system. We make improvements to their kill switch by increasing the kill switch's specificity, increasing efficiency, and employing a more effective killing mechanism using our chassis.
