Team:DTU-Denmark/Model

Substrate Set

Our substrate screening experiment produced a large number of interesting substrates for our detection assay. We looked at the raw fluorescence measurements, but we also applied statistical analysis to identify the peptides that had significant differences between the three venoms. In addition, we modelled the enzymatic activity of the venoms based on our measurements.

Figure 1: Significant substrates found in our experiment, by looking at the signal difference between the three snakes after the 60 minutes timepoint. BA represents Bitis arietans, BG represents Bitis gabonica and NN Naja nigricollis. Significance here is defined by log10(p) < -9.

You can find the plots of logarithmic fluorescence signal and time of all the substrates here

LacZ Device

• Substrate Set
• LacZ Device

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