Team:FSU/Team

Team:FSU/Team - 2017.igem.org

Team:FSU/Team

FSU

Team:FSU/Team - 2017.igem.org

Team:FSU/Team

team

Justin
Bartell

Team Lead

My responsibilities reside in focusing on the overarching goals for the iGEM competition and setting deadlines for the team to reach those goals. I brainstorm with each workgroup, gather resources for the workgroups, and play a major role in the fundraising campaign. Mainly, I give my team members the space to become experts in their part of the project while making sure we’re on the path to a gold medal!

William
Hochstedler

Associate Team Lead

Responsibilities are securing locations for meetings, organizing social events, corresponding with SGA to get iGEM registered as a student organization, helping team leader and members wherever necessary (fundraising, keeping teams updated, corresponding with advisors).

Isabel
Lamb

Head of Create Team

Responsible for building and testing the cell designs, oversees testing protocols and responsible for a system of naming the designs. Has done transformations, plasmid preps, restriction cuts, run gels and done gel purifications.

Westin
Kosater

Create Team Member

Responsible for testing protocols and is the Vice Chancellor of Enzyme stocks. Has done plasmid mini preps, restriction digests and testing of E-coli constructs.

Megan
Donnely

Create Team Member

Responsibilities have been the development of assembly protocols for our different construct designs and the coordination of the submission of parts. to the IGEM registry alongside my teammate, Wes.

Damilola
Ologunagba

Create Team Member

Responsible for the Interlab Study. Has done the transformations, plasmid preps, restriction cuts, gels purifications. In the lab, since the G blocks we ordered arrived, we've TOPO cloned 2 gliadin degraders and 2 gliadin sponges, we've selected 8 Anderson promoters each representing different gene expression strengths because we don't know which promoter will work best, so we will try each one. Hopefully we will have 32 constructs for testing . I'm in charge of determining the flow of the interlab-study.)

Andrew
Chacko

Head of Design Team

Responsible for understanding the problem, detailing three workable designs, ordering parts, and collaborating with Create team. Has performed literature reviews for all modules, determined best approach to problem, created Python notebooks detailing build, chosen Promoters, RBS and terminator used, diagramed designs on Visio, ordered gBlocks from IDT, incorporated testing parameters provided by the Create Team, determined best designs to pursue, designed workable gBlocks that allow for modularity, checked for illegal cut sites on the CDS, collaborated with University of Lethbridge to determine design overlaps and defined FASTA files.

Nicholas
Cooper

Design Team Member

Conducted literature search on zonulin, literature search on potential ways to get gliadin/zonulin receptor to membrane, literature search on kinetics of kumamax on gliadin and Created initial device in cell sketch for zonulin receptor cell, Aided in modeling gliadin degrader using PySB and in modeling receptors using PySB.

Alexander
Mangas

Design Team Member

Performed extensive literature review, developed a preliminary design for the Gliadin Degrader Cop Cell, created predictive analytic models for the Gliadin Degrader Cop Cell and a comparative model combining the gliadin Degrader & Cuff Small Intestine Cop Cell using python in PySB, improved model functionality by incorporating Compartment-based modeling into a rule-based model in order to enable explicit definition of volume, aided in the development of empirical testing methods for experimentally determining the efficacy of cell constructs

Savannah
Shewan

Head of Human Practices Team

Worked to organize Human Practices efforts including community involvement, contacting participants (Celiac patients, Gastroenterologists, and members of the community). Helped to compose the scripted Presentation for the iGEM Jamboree, organized content for the final poster, and coded portions of the wiki. As well as, ran final checks on questions, content, and graphics used as part of FSU’s iGEM project.

Ada
Del Cid

Human Practices Team Member

ATTRIBUTION

Sterling
Strmel

Human Practices Team Member

Responsible for speaking with people with Celiac Disease, doctors and general public. Helped develop Moonshot Night survey, integrated Human Practices into the project, designed graphics and slides for the Presentation, designed preliminary poster for the project and for Moonshot Night, and started working on a video series collaboration-outreach effort with the University of Florida.

Harrison
Schwartz

Human Practices Team Member

Has developed a strategic fundraising plan for the FSU iGEM team, reached out to companies nationwide and throughout the state of Florida as well as partnering with the CDF and local support groups for Celiac Disease. Has been working all summer to find a sponsor or partnership for the team.

Erin
Smyth

Human Practices Team Member

ATTRIBUTION

Advisors

Dr George
Wadhams

Supervisor

George Wadhams’ research interests lie in how bacteria sense and integrate environmental information. His group focuses on understanding in a quantitative manner how multiple, homologous pathways operate in individual cells and how the components of these pathways can be used to create synthetic pathways.

Dr Chris
Jones

Supervisor

For optimum growth bacteria must adapt to their environment, one way to do this is by moving towards advantageous conditions. To do this they must be able to both move and to control the direction of that movement. The signaling pathways that control this directionality form into large arrays of receptors and kinases. The best studied arrays contain transmembrane receptors, however many species also contain arrays that are non-transmembrane and therefore in the cytoplasm. My work focuses on the cytoplasmic chemoreceptor array of Rhodobacter sphaeroides. Looking at both how the array is formed and stabilised without the presence of a membrane and how the array is split and segregated prior to cell division insuring faithful inheritance of the complete chemotaxis pathway.

Professor Judy
Armitage

Advisor

Judy Armitage is interested in the dynamics of bacterial sensory transduction and the control of bacterial motility. In particular, her research group focuses on the communication between the sensory and adaption mechanisms of the two pathways as a model for sensory network integration in general..

Professor Anthony
Watts

Advisor

Anthony Watts’ group is devising solid state NMR methods for determining high-resolution details of information-rich sites within membrane receptors. Recent focus has been on the neurotensin receptor (NTS1), which is now available highly purified and monodispersed in detergent as well as in a ligand-binding form.

Professor Antonis
Papachristodoulou

Advisor

Antonis Papachristodoulou’s research interests include systems and synthetic biology, network systems, aerospace systems and flow control, and convex optimisation. Furthermore, he works on modern control theory, robust stability analysis and design, as well as nonlinear dynamical systems and Lyapunov stability.

Andreas
Harris

Advisor

Andreas Harris works on the design and implementation of gene regulatory networks harnessing feedback to increase robustness and tunability. The designs are based around transcriptional networks and attempt to translate well-understood control modules, such as proportional and integral controllers, to biological systems.

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