Difference between revisions of "Team:UCSC/Acetaminophen"

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We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine <sup>[1]</sup>. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide <sup>[23]</sup>.  Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals <sup>[24]</sup>.
 
We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine <sup>[1]</sup>. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide <sup>[23]</sup>.  Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals <sup>[24]</sup>.
 
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Revision as of 22:07, 14 September 2017


Acetaminophen Metabolics

"Antipyretic drugs, by being analgesics, reduce not only the fever but also the pain."

~Clinical Manual of Fever in Children




We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine [1]. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide [23]. Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals [24].