Difference between revisions of "Team:UCSC/Acetaminophen"
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We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine <sup>[1]</sup>. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide <sup>[23]</sup>. Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals <sup>[24]</sup>. | We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine <sup>[1]</sup>. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide <sup>[23]</sup>. Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals <sup>[24]</sup>. | ||
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| + | <li>[1] World Health Organization, ed.,<span class="reference-italic">The Selection and Use of Essential Medicines: report of theWHO Expert Committee, 2007 ; (including the 15th model list of essential medicines).</span> No. 946in WHO Technical Report Series, Geneva: World Health Organization, 2007. OCLC: 254437808.</li> | ||
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Revision as of 22:16, 14 September 2017
Acetaminophen Metabolics
"Antipyretic drugs, by being analgesics, reduce not only the fever but also the pain."
~Clinical Manual of Fever in Children
We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine [1]. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide [23]. Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals [24].
