Team:UCSC/Acetaminophen
Acetaminophen Metabolics
"Antipyretic drugs, by being analgesics, reduce not only the fever but also the pain."
~Clinical Manual of Fever in Children
We aim to genetically modify PCC 7942 to produce acetaminophen, a common mild anes-thetic and antipyretic recognized by the WHO as an essential medicine [1]. However, in many countrieswith lower regulations and faulty policies regarding drug manufacturing, acetaminophen can be syn-thesized with lethal toxins that result in hundreds of deaths worldwide [23]. Acetaminophen is oftenused in conjunction with opioid pain medications postoperatively to enhance pain relief, thus reducingreliance upon opioid pharmaceuticals [24].
