Team:Freiburg/Introduction

Overview Motivation CAR T Cells Tumor Microenvironment AND Gate Outlook Achievements References

Members Attributions Partners Contact

Main Project Modeling Applied Design Proof of Concept BioBricks Basic Part BioBrick Improvement Interlab Study

Safety Cloning HIF1A Knockdown Cell Culture Lab Book

Human Practice Integrated Human Practice Collaborations

CARTEL^TM T cells act like ‘good’ mafia enforcers, as they eliminate the tumor cells which are undesired intruders into the mafia’s territory where they compete with the body’s healthy cells. In our CARTEL^TM system the T cells specifically target tumors by their microenvironment, unlike the ‘bad’ mafia in current CAR therapy where off-target effects occur like collateral damage caused by real world mafias. The CARTEL^TM mafia is peaceful when no tumor is present, however, if the CARTEL^TM finds cancer this gang of CAR T cells effectively eliminates the invasion.

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Motivation