Difference between revisions of "Team:IISc-Bangalore"

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           <div style="position: absolute; right: 5%; width: 20%; font-size: 2.3em; line-height: 1.4; font-family: 'Poppins'; top: 55%; transform: translateY(-50%);"> Potential future applications of buoyant clusters of bioengineered gas vesicles include bioremediation of oil spills and flotation-based separation and purification of specific targets from mixtures.</div>
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           <div style="position: absolute; right: 5%; width: 25%; font-size: 2.3em; line-height: 1.4; font-family: 'Poppins'; top: 55%; transform: translateY(-50%);"> Potential future applications of buoyant clusters of bioengineered gas vesicles include bioremediation of oil spills, flotation-based separation, and purification of specific targets from mixtures!</div>
 
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Revision as of 02:53, 2 November 2017

Gas vesicles (GVs) are hollow protein nanostructures synthesized by phototrophic haloarchaea and cyanobacteria to regulate their flotation in aquatic habitats.
Bioengineered GVs have been genetically modified for diverse purposes; ultrasonic molecular imaging, gauging cellular turgor pressures, and vaccine delivery - but none of their current applications exploits their most fundamental characteristic: buoyancy.
Our modelling shows clusters of GVs that float enormously better than individual GVs.
Our project iFLOAT aims to improve the flotation of gas vesicles by clustering them using three distinct methods — charge-based flocculation, biotin-streptavidin interaction, and SpyCatcher-SpyTag heterodimerization
Potential future applications of buoyant clusters of bioengineered gas vesicles include bioremediation of oil spills, flotation-based separation, and purification of specific targets from mixtures!
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