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Revision as of 06:06, 11 October 2017

Project | ecDNA Cancer


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PROJECT OVERVIEW



Cancer, a genetic disease resulting in uncontrollable cell growth, is mostly caused by somatic mutations acquired throughout an individual’s lifetime. Recently, it was discovered that some oncogenes resided on extrachromosomal DNA (ecDNA). Because ecDNA causes oncogene copy number to increase exponentially, utilizing CRISPR to create breaks in ecDNA decreases cancer cells’ replication speed.

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>

PROJECT OVERVIEW



Cancer, a genetic disease resulting in uncontrollable cell growth, is mostly caused by somatic mutations acquired throughout an individual’s lifetime. Recently, it was discovered that some oncogenes resided on extrachromosomal DNA (ecDNA). Because ecDNA causes oncogene copy number to increase exponentially, utilizing CRISPR to create breaks in ecDNA decreases cancer cells’ replication speed.

FIND OUT MORE