Difference between revisions of "Team:UCL"

 
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     <title>UCL LIT</title>
 
     <title>UCL LIT</title>
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                     <li><a href="https://2017.igem.org/Team:UCL/Description" class="dropped">Description</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/Description" class="dropped">Description</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/Results" class="dropped">Results</a></li>
 
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                     <li><a href="https://2017.igem.org/Team:UCL/Parts" class="dropped">Basic Parts</a></li>
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                    <li><a href="https://2017.igem.org/Team:UCL/Composite_Part" class="dropped">Composites</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/Part_Improvement" class="dropped">Gold Part</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/Part_Improvement" class="dropped">Gold Part</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/InterLab" class="dropped">Interlab</a></li>
 
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                     <li><a href="https://2017.igem.org/Team:UCL/Engagement" class="dropped">Public Engagement</a></li>
 
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                     <li><a href="https://2017.igem.org/Team:UCL/HP/Gold_Integrated" class="dropped">Integrated Practices</a></li>
 
                     <li><a href="https://2017.igem.org/Team:UCL/HP/Gold_Integrated" class="dropped">Integrated Practices</a></li>
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                    <li><a href="https://2017.igem.org/Team:UCL/HP/Silver" class="dropped">HP Silver</a></li>
 
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            <li id="drop5" class="navy-link"><a href="#">MODELLING</a>
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        <li id="drop5" class="navy-link"><a href="https://2017.igem.org/Team:UCL/Model">MODELLING</a>
 
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                     <li><a href="https://2017.igem.org/Team:UCL/Model" class="dropped">Overview</a></li>
 
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                     <li><a href="https://2017.igem.org/Team:UCL/Entrepreneurship" class="dropped">Overview</a></li>
 
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             <li id="drop4" class="navy-link"><a href="https://2017.igem.org/Team:UCL/Notebook">LAB BOOK</a></li>
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                         <div style="border:none" class="text-section">
 
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                             <p style="font-size: 18px; font-weight: 200" class="intro-homepage">UCL iGEM 2017 presents</p>
 
                             <p style="font-size: 18px; font-weight: 200" class="intro-homepage">UCL iGEM 2017 presents</p>
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<p class="intro-homepage">LIT(Light Induced Technologies)</p>
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<p class="intro-homepage">LIT (Light Induced Technologies)</p>
 
                             <p class="text-content-new">We developed applications for biological light switches. The mission was to standardise optogenetic tools for wider use in synthetic biology and to show how we can apply them in tissue engineering, building architectural structures and producing bacterial light bulbs.</p>
 
                             <p class="text-content-new">We developed applications for biological light switches. The mission was to standardise optogenetic tools for wider use in synthetic biology and to show how we can apply them in tissue engineering, building architectural structures and producing bacterial light bulbs.</p>
 
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<p class="pop-text">We used biological light switches to design an organ printing system</p>
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<p class="pop-text">We developed a novel tissue engineering approach based on the use of an optogenetic guidance system that will allow scaffold-free, precise control of cellular behaviour using light switches.<span style="color: red"> </span></p>
 
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<p class="pop-text">We combined a photosensitive protein with co-culturing E. Coli and cyanobacteria to design a bioluminescent light bulb. During day time, the photosensitive protein suppresses the bioluminescent ability of engineered E. Coli, while cyanobacteria photosynthesise and produce the necessary glucose for their neighbours. Through our conceptual prototype, we achieve both powerful illumination and sustainability in our light-bulb.</p>
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<p class="pop-text">We developed and prototyped a bacterial light-bulb - one that uses light-repressible bioluminescence and co-culturing to create an efficient and sustainable solution for public illumination. </p>
 
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<p class="pop-text">We used a <span style="color: red">photosensitive protein</span> and a <span style="color: green">photocaged non-natural amino acid</span> to make 2 light-induced gene activation systems for a 3D printing technology that only uses bacteria as raw material. Guided by light, cells form <span style="color: #24b4ff">3D structures</span> through adhering to each other and then produce the <span style="color: black">PHB biopolymer</span>, secreting it and layering the material in the already formed structure.</p>
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<p class="pop-text">We developed transcriptional and post-translational light switches for the induction of cell adhesion. Guided by light, cells will be directed to form 3D structures by adhering to each other and simultaneously producing, secreting and binding a desired polymer that can be then crosslinked into a solid 3D shape.</p>
 
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Latest revision as of 23:51, 1 November 2017

UCL LIT

UCL iGEM 2017 presents

LIT (Light Induced Technologies)

We developed applications for biological light switches. The mission was to standardise optogenetic tools for wider use in synthetic biology and to show how we can apply them in tissue engineering, building architectural structures and producing bacterial light bulbs.

We developed a novel tissue engineering approach based on the use of an optogenetic guidance system that will allow scaffold-free, precise control of cellular behaviour using light switches.

We developed and prototyped a bacterial light-bulb - one that uses light-repressible bioluminescence and co-culturing to create an efficient and sustainable solution for public illumination.

We developed transcriptional and post-translational light switches for the induction of cell adhesion. Guided by light, cells will be directed to form 3D structures by adhering to each other and simultaneously producing, secreting and binding a desired polymer that can be then crosslinked into a solid 3D shape.