Difference between revisions of "Team:SiCAU-China"

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<title>SiCAU-iGEM</title>
 
<title>SiCAU-iGEM</title>
 
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<div align="center" class="STYLE1"><img src="https://static.igem.org/mediawiki/2017/f/ff/T-SICAU-EYEZHUAN666.png" width="100%" height="100%" /></div>
 
<div align="center" class="STYLE1"><img src="https://static.igem.org/mediawiki/2017/f/ff/T-SICAU-EYEZHUAN666.png" width="100%" height="100%" /></div>
 
<div style="clear:both;"></div>
 
<div style="clear:both;"></div>
 
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<div id="float">
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<div class="navigation">
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  <div id="team-icon"><a href="https://2017.igem.org/Team:SiCAU-China"> <img src="https://static.igem.org/mediawiki/2017/2/2c/T-SICAU-Sherlock_E.coli.jpg" alt="club's logo" /> </a></div>
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  <div class="navigation-menu">
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    <li><a href="#"><div>
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<img src="https://static.igem.org/mediawiki/2017/thumb/5/5b/T-SICAU-magnifier.jpg/180px-T-SICAU-magnifier.jpg.png" alt="project" class="up-nav-icon" />project</div></a>
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        <div class="dropdown-content">
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<a href="https://2017.igem.org/Team:SiCAU-China/Description">Description</a>
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<a href="https://2017.igem.org/Team:SiCAU-China/Design">Design</a>
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  <a href="https://2017.igem.org/Team:SiCAU-China/Results">Results</a>
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                  <a href="https://2017.igem.org/Team:SiCAU-China/Contribution">Contribution</a> 
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<li><a href="#"><div>
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<img src="https://static.igem.org/mediawiki/2017/thumb/c/c3/T-SICAU-letter_opener.jpg/180px-T-SICAU-letter_opener.jpg.png" alt="Model" class="up-nav-icon" />
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        <a href="https://2017.igem.org/Team:SiCAU-China/Model">Model</a></div></a>
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    <li><a href="#"><div>
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<img src="https://static.igem.org/mediawiki/2017/thumb/7/77/T-SICAU-hat.jpg/105px-T-SICAU-hat.jpg.png" alt="practice" class="up-nav-icon" />
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<a href="https://2017.igem.org/Team:SiCAU-China/HP/Silver">practice</a></div></a>
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    <li><a href="#"><div>
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<img src="https://static.igem.org/mediawiki/2017/thumb/a/ab/T-SICAU-door.jpg/180px-T-SICAU-door.jpg.png" alt="Notebook" class="up-nav-icon" />
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        <a href="https://2017.igem.org/Team:SiCAU-China/Notebook">Notebook</a></div></a>
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<li><a href="#"><div>
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<img src="https://static.igem.org/mediawiki/2017/thumb/7/7f/T-SICAU-team.jpg/120px-T-SICAU-team.jpg.png" alt="team" class="up-nav-icon" />team</div></a>
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        <div class="dropdown-content">
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<a href="https://2017.igem.org/Team:SiCAU-China/Team">Team</a>
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<a href="https://2017.igem.org/Team:SiCAU-China/Collaborations">Collaborations</a></div></li>
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        <li><a href="#"><div>
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        <img src="https://static.igem.org/mediawiki/2017/thumb/a/a6/T-SICAU-pipe.jpg/180px-T-SICAU-pipe.jpg.png" alt="Attributions" class="up-nav-icon" />
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          <a href="https://2017.igem.org/Team:SiCAU-China/Attributions">Attributions </a></div></a>
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</div>
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</div>
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<div style="clear:both;"></div>
 
<h1 align="center" class="STYLE6"><i>Sherlock E.coli</i> : A Sensitive Positive Feedback Detector</h1>
 
<h1 align="center" class="STYLE6"><i>Sherlock E.coli</i> : A Sensitive Positive Feedback Detector</h1>
 
<p style="font-size:16px;width: 94%;margin: 0 auto;color:#CCCCCC">
 
<p style="font-size:16px;width: 94%;margin: 0 auto;color:#CCCCCC">

Revision as of 13:06, 17 October 2017

SiCAU-iGEM

Sherlock E.coli : A Sensitive Positive Feedback Detector

Positive feedback system can be found in everywhere, existed widely in creature contained from Lac operon of prokaryotes to human beings, and it has been used to construct various attractive circuits such bistable state, oscillators and other inconceivable systems. In our project this year, the significant performance of sensitivity, which researchers has not concerned to, will be developed in positive feedback loop established by LuxR/LuxI quorum sensing system. But this loop will be open because of its background expression. The AiiA, which can hydrolyze the AHL, will be control the background expression, together with the Lac operon being the system main switch. Furthermore, the input defined by user will have a negative correlation to the opening time. Hence, there need a model to describe this relation and even realize quantitative determination.

more coming soon ......