Medals

Bronze

• Team registered and ready for Jamboree
• Wiki and posters finished (see us and our poster in zone 5 in Hall D on the second floor, stall 259)
• Presentation ready and waiting
• Check in, safety and judging forms completed
• Parts documented on and samples submitted to Registry
• Attributions done on attributions page
• Added to characterisation of [http://parts.igem.org/Part:BBa_J23111:Experience BBa_J23111], [http://parts.igem.org/Part:BBa_K808000:Experience BBa_K808000] and [http://parts.igem.org/Part:BBa_E0040:Experience BBa_E0040]
• Completed Interlab measurements

Silver

• Characterized our 15b-GFP toehold switch and it works
• Added our parts to [http://parts.igem.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2017&group=CLSB-UK the registry]
• We collaborated with Judd-UK, Westminster, Carroll HS, EPFL and Oxford
• Detailed silver human practices and plenty of engagement, including creating the high school teams guide.

Gold

• Integrated human practices into every part of the project
• Improved the design of Aachen’s fluorometer, and then built our own
• Modelled just about everything - including the structure of our switches, the reaction kinetics, the uncertainties on our model and the cost-effectiveness of a screening programme with our test.
• We’ve demonstrated it all works

Key Papers

Explanation of why we have this list - i.e. we used lots of sources (maybe a stat from page with most sources - likely to be homepage/design/HP gold/HP silver), want to make it easier for judges/other teams reviewing our wiki etc.

Toehold Switches, their design and use

• Green, A. A., Silver, P. A., Collins, J. J., & Yin, P. (2014). Toehold switches: de-novo-designed regulators of gene expression. Cell, 159(4), 925-939. DOI: 10.1016/j.cell.2014.10.002
• Green, A. A., Kim, J., Ma, D., Silver, P. A., Collins, J. J., & Yin, P. (2016, September). Ribocomputing devices for sophisticated in vivo logic computation. In Proceedings of the 3rd ACM International Conference on Nanoscale Computing and Communication (p. 11). ACM. DOI: 10.1145/2967446.2970373
• Pardee, K., Green, A. A., Takahashi, M. K., Braff, D., Lambert, G., Lee, J. W., ... & Daringer, N. M. (2016). Rapid, low-cost detection of Zika virus using programmable biomolecular components. Cell, 165(5), 1255-1266. DOI: 10.1016/j.cell.2016.04.059
• Machinek, R. R., Ouldridge, T. E., Haley, N. E., Bath, J., & Turberfield, A. J. (2013). Programmable energy landscapes for kinetic control of DNA strand displacement. Nature communications, 5, 5324-5324. DOI: 10.1038/ncomms6324

Micro-RNAs as Biomarkers

• Hennessey, P. T., Sanford, T., Choudhary, A., Mydlarz, W. W., Brown, D., Adai, A. T., ... & Califano, J. A. (2012). Serum microRNA biomarkers for detection of non-small cell lung cancer. PloS one, 7(2), e32307. DOI: 10.1371/journal.pone.0032307
• Etheridge, A., Lee, I., Hood, L., Galas, D., & Wang, K. (2011). Extracellular microRNA: a new source of biomarkers. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 717(1), 85-90. DOI: 10.1016/j.mrfmmm.2011.03.004

Wiki

TODO: Write about how our wiki is so good with SVGs, compressed images, correctly sized iamges, lots of reviewing of text (maybe a fact about the total number of comments?), how we thought about the navbar, consistent style, used mediawiki templates, shared our knowledge with other teams (Caroll, Westminster, Judd)

All our code was written by current team members, except the small bits otherwise attributed. All images which we didn't make ourselves are attributed beneath the image. Images without explicit licenses are reproduced with written consent of the rights holders.

Jamboree

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Come visit our stall - we are in zone 5 in Hall D on the second floor, stall 259

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Presentation

Come watch our presentation at 3:30 on Friday in Ballroom B.