Difference between revisions of "Team:SHSBNU China/Applied Design"

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    <title>SHSBNU-China iGEM 2017 Home Page</title>
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<h3>★  ALERT! </h3>
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<p>This page is used by the judges to evaluate your team for the <a href="https://2017.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2017.igem.org/Judging/Awards"> award listed above</a>. </p>
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2017.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
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<h1>Applied Design</h1>
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<h3>Best Applied Design Special Prize</h3>
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<p>This is a prize for the team that has developed a synbio product to solve a real world problem in the most elegant way. The students will have considered how well the product addresses the problem versus other potential solutions, how the product integrates or disrupts other products and processes, and how its lifecycle can more broadly impact our lives and environments in positive and negative ways.
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<br><br>
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To compete for the <a href="https://2017.igem.org/Judging/Awards">Best Applied Design prize</a>, please describe your work on this page and also fill out the description on the <a href="https://2017.igem.org/Judging/Judging_Form">judging form</a>.
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<br><br>
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You must also delete the message box on the top of this page to be eligible for this prize.
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</p>
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</div>
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<div class="column half_size">
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<body class="home blog logged-in admin-bar no-customize-support" >
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    <div style="overflow: hidden; z-index: -1; position: fixed; height: 100%; width: 100%; top: 0px; left: 0px; ">
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        <img  id="background_picture" src="https://static.igem.org/mediawiki/2017/e/ee/SHSBNU_17_background.jpg" style="position: fixed; display: block; left: 0px; top: 0px;">
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    </div>
  
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<h5>Inspiration</h5>
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    <div id="wrap">
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<p>Take a look at what some teams accomplished for this prize.</p>
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        <div id="branding">
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<ul>
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            <a href="https://2017.igem.org/Team:SHSBNU_China"> <img src="https://static.igem.org/mediawiki/2017/a/aa/SHSBNU_17_Banner.jpg" /></a>
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<li><a href="https://2016.igem.org/Team:NCTU_Formosa/Design">2016 NCTU Formosa</a></li>
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        </div>
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<li><a href="https://2016.igem.org/Team:HSiTAIWAN/Product?locationId=Design">2016 HSiTAIWAN</a></li>
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<li><a href="https://2016.igem.org/Team:Pasteur_Paris/Design">2016 Pasteur Paris</a></li>
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</ul>
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</div>
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<div class="clear"></div>
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        <div id="nav">
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        <nav class = "main" style = "font-size:16px; text-align: center;" >
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Project" style = "opacity: 1;">Project</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Model" style = "opacity: 1;">Model</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/HP" style = "opacity: 1;">HP</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Safety" style = "opacity: 1;">Safety</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Parts" style = "opacity: 1;">Parts</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Team" style = "opacity: 1;">Team</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Achievement" style = "opacity: 1;">Achievement</a>
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        </nav>
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        </div>
  
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        <div id = "nav">
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        <nav class = "title" style = "font-size:20px; text-align: center">
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            <p style = "font-family:arial;color:#444;font-size:30px; text-align: center">Project</p>
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        </nav>
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        </div>
  
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        <div id="nav">
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        <nav class = "cate" style = "font-size:16px; text-align: center;" >
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Project" style = "opacity: 1;">Project</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Experiment" style = "opacity: 1;">Experiment</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Improve" style = "opacity: 1;">Improve</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Demonstrate" style = "opacity: 1;">Demonstrate</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Applied_Design" style = "opacity: 1;">Applied Design</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/Protocol" style = "opacity: 1;">Protocol</a>
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            <a> | </a>
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            <a href="https://2017.igem.org/Team:SHSBNU_China/InterLab" style = "opacity: 1;">InterLab</a>
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        </nav>
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        </div>
  
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        <div class="post-75 post type-post status-publish format-standard hentry category-azir-quantum-science concavebox">
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            <div class="entry" style="opacity: 0.95;">
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                <p style = "font-family:arial;color:#444444;font-size:32px; text-align: center">  Applied Design</p>
  
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                <p style = "font-family:arial;color:#000000;font-size:20px; text-align: left"> Applied Capsule ingredient statement</p>
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                <img src="https://static.igem.org/mediawiki/2017/5/57/SHSBNU_17_14a003.jpg"/>
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                <img src="https://static.igem.org/mediawiki/2017/1/1c/SHSBNU_17_13a00.jpg" style="height:100px"/>
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                <img src="https://static.igem.org/mediawiki/2017/d/df/SHSBNU_17_14a001.jpg" style="height:120px"/>
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                <p>(The structure of polyacrylic)</p>
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                <br/>
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                <p>At the inside of capsule, it contains polyacrylic resin to control the dissolving process of the capsule. Polyacrylic is made from Methacrylic acid, Methyl propiolate and acrylic ester in different proportion. Nowadays, polyacrylic resin II and III are the common material used in coating. The effective portion of polyacrylic resin is its carboxyl. When polyacrylic resin in low PH environment, the carboxyl will combine with hydroxyl ion and form salt, so that it is easier for bacteria to pass through. </p>
  
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                <p style = "font-family:arial;color:#000000;font-size:20px; text-align: left"> Storage information</p>
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                <p>The probiotic medicinal product contains viable bacteria in a high concentration. For this reason, it should be stored in a refrigerator at a temperature ranging between +2° C and +8° C. An interruption of chilling for a few days will have normally no influence on the number of viable cells. Therefore it is much available for patients to get effective products. </p>
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                <img src="https://static.igem.org/mediawiki/2017/a/aa/SHSBNU_17_14a002.jpg" style="height:250px"/>
  
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                <p style = "font-family:arial;color:#000000;font-size:20px; text-align: left"> Safety</p>
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                <p>In case of a prolonged heat exposure, however, the bacterial cells will to some extent lose their viability. No toxic substances will be developed. </p>
  
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                <p style = "font-family:arial;color:#000000;font-size:20px; text-align: left"> Sensitivity</p>
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                <p>Because the capsule ingredient has been designed consummately, we can make sure the bacteria will not be released in wrong position, so these bacteria will work intensively. Specific speaking, our engineered bacteria show distinct color-depth difference when exposed to different concentrations of tetrasulfate and thiosulfate, ranging from 0.01 mM to 1mM. The probiotics are able to produce (Flow-process is following), and there will be an obvious result when the chromoprotein mix with excrement for we have down an experiment about color modulation (the result is following)</p>
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                <p><a href="https://static.igem.org/mediawiki/2017/5/53/SHSBNU_17_10a00.jpg"></a></p>
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                <p><a href="https://static.igem.org/mediawiki/2017/b/b3/SHSBNU_17_20b00.jpg"></a></p>
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                <p style = "font-family:arial;color:#000000;font-size:20px; text-align: left"> Reference</p>
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                <p>杜德才. (2001). 肠溶包衣材料在药物制剂中的应用. <i>中国药业,</i> 10(5), 62-63.</p>
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            </div><!-- .entry -->
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        <div class="entry-footer" align = "center">
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            <a href="http://www.shsbnu.net" style = "float:left"><img src = "https://static.igem.org/mediawiki/2017/4/44/SHSBNU_Logo_256X256.jpg" style="height:48px; width:48px; " border=0></a>
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            <a href="http://www.azirquantum.net.cn" style = "float:left"><img src = "https://static.igem.org/mediawiki/2017/1/1f/Azir_Logo_256X256.jpg" style="height:48px; width:48px; " border=0></a>
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            <a href="https://2017.igem.org" style = "float:right"><img src = "https://static.igem.org/mediawiki/2017/6/60/IGEM_Logo_256X256.jpg" style="height:48px; width:48px; " border=0></a>
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            <a href="http://www.bluepha.com" style = "float:right"><img src = "https://static.igem.org/mediawiki/2017/b/bc/Bluepha_Logo_256X256.jpg" style="height:48px; width:48px; " border=0></a>
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            <P style = "font-family:arial;color:#5C5C5C;font-size:10px; text-align: center">iGEM 2017</P>
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            <P style = "font-family:arial;color:#5C5C5C;font-size:10px; text-align: center">Made by Azir.</P>
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            <p style = "font-family:arial;color:#5C5C5C;font-size:10px; text-align: center">The Second High School Attached Beijing Normal University International Division </p>
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        </div>
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    </div><!-- .concavebox -->
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</body>
 
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Latest revision as of 16:10, 1 November 2017

SHSBNU-China iGEM 2017 Home Page

Applied Design

Applied Capsule ingredient statement

(The structure of polyacrylic)


At the inside of capsule, it contains polyacrylic resin to control the dissolving process of the capsule. Polyacrylic is made from Methacrylic acid, Methyl propiolate and acrylic ester in different proportion. Nowadays, polyacrylic resin II and III are the common material used in coating. The effective portion of polyacrylic resin is its carboxyl. When polyacrylic resin in low PH environment, the carboxyl will combine with hydroxyl ion and form salt, so that it is easier for bacteria to pass through.

Storage information

The probiotic medicinal product contains viable bacteria in a high concentration. For this reason, it should be stored in a refrigerator at a temperature ranging between +2° C and +8° C. An interruption of chilling for a few days will have normally no influence on the number of viable cells. Therefore it is much available for patients to get effective products.

Safety

In case of a prolonged heat exposure, however, the bacterial cells will to some extent lose their viability. No toxic substances will be developed.

Sensitivity

Because the capsule ingredient has been designed consummately, we can make sure the bacteria will not be released in wrong position, so these bacteria will work intensively. Specific speaking, our engineered bacteria show distinct color-depth difference when exposed to different concentrations of tetrasulfate and thiosulfate, ranging from 0.01 mM to 1mM. The probiotics are able to produce (Flow-process is following), and there will be an obvious result when the chromoprotein mix with excrement for we have down an experiment about color modulation (the result is following)

Reference

杜德才. (2001). 肠溶包衣材料在药物制剂中的应用. 中国药业, 10(5), 62-63.

iGEM 2017

Made by Azir.

The Second High School Attached Beijing Normal University International Division