Difference between revisions of "Team:RPI Troy NY"

 
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<td align="center"><h3>Welcome to Team RPI_TROY_NY 2017!</h3>
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<td align="center"><p>Scroll down to find more about our project! </p>
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<font face = "Palatino"><font size = "8">Welcome to Team RPI_TROY_NY 2017!</h1></font>
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<p> <font face= "Century Gothic"> <font size = "4"> <h5>Project Description </h5> </font>
 
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<font face= "Times New Roman"> <font size = "3">Sophorolipids are a yeast-derived (Starmerella bombicola), non-toxic and biodegradable alternative to conventional petroleum-derived surfactants and detergents. Currently, the main barrier to commercial production is the cost of isolating and refining sophorolipids of useful chain length. Sophorolipid production competes with the beta-oxidation pathway in yeast for fatty acid substrates, thus lowering yield and producing a mixture of products. The enzyme MFE-2 is a critical component of the beta oxidation pathway. Through genetic engineering, we will selectively repress active domains of this enzyme with the intent of increasing the yield of sophorolipid product. By employing a repression technique rather than a full knockout of the gene, the stress on the yeast metabolism will be reduced.</font> </p>
 
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<p> "Nature doesn't make things like that," said Kenneth Peters, an organic geochemist at Stanford University, "so organisms have never seen that before." </p>
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<p> <font face= "Century Gothic"> <font size = "4"> <h5> Our Project </h5> </font>
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<font face= "Times New Roman"> <font size = "3">Sophorolipids are a yeast-derived (<i>Starmerella bombicola</i>), non-toxic and biodegradable alternative to conventional petroleum-derived surfactants and detergents. Currently, the main barrier to commercial production is the cost of isolating and refining sophorolipids of useful chain length. Sophorolipid production competes with the beta-oxidation pathway in yeast for fatty acid substrates, thus lowering yield and producing a mixture of products. The enzyme MFE-2 is a critical component of the beta oxidation pathway. Through genetic engineering, we aim to selectively repress active domains of this enzyme with the intent of increasing the yield of sophorolipid product. By employing a repression technique rather than a full knockout of the gene, the stress on the yeast metabolism may be reduced.<br><br>Our research was formally recognized with a Bronze Medal award at the 2017 iGEM Giant Jamboree.</font> </p>
  
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<h3> How our project will be helpful?</h3>
 
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<p> All over the world, pollution is a huge problem. People are so reckless and unconcious about pollution and recycling, precautions of governments are usually insufficient. For example, Americans generate abo¬ut 210 million tons (231 million short tons) of trash, or solid waste, each year. Most of this trash (57 percent) gets placed in municipal landfills. About 56 million tons (27 percent) is recovered through either recycling, (such as glass, paper products, plastic or metals) or through composting.
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So we wanted to make people conscious of pollution and importance of recycling, also tried to give a solution for cleaning enviroment from this toxic waste because it is known that plastics contain toxic chemicals such as bisphenol A (BPA) and PS oligomers.
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Freudenrich,C., (2014) How Composting Works. Retrieved from
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<a class="twitter-timeline" href="https://twitter.com/iGEM_METU2014" data-widget-id="499378473245229057">@iGEM_METU2014 kullanıcısından Tweetler</a>
 
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Latest revision as of 19:51, 14 December 2017

Home Team Collaborations Project Results
Interlab Study Safety Human Practices Attributions

Welcome to Team RPI_TROY_NY 2017!

Our Project
Sophorolipids are a yeast-derived (Starmerella bombicola), non-toxic and biodegradable alternative to conventional petroleum-derived surfactants and detergents. Currently, the main barrier to commercial production is the cost of isolating and refining sophorolipids of useful chain length. Sophorolipid production competes with the beta-oxidation pathway in yeast for fatty acid substrates, thus lowering yield and producing a mixture of products. The enzyme MFE-2 is a critical component of the beta oxidation pathway. Through genetic engineering, we aim to selectively repress active domains of this enzyme with the intent of increasing the yield of sophorolipid product. By employing a repression technique rather than a full knockout of the gene, the stress on the yeast metabolism may be reduced.

Our research was formally recognized with a Bronze Medal award at the 2017 iGEM Giant Jamboree.