Difference between revisions of "Team:HUST-China"

 
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                             TEAM <b class="caret"></b>
 
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            <h1 class="tab-h1" ><strong>「Background」</strong></h1>
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                    <li class="active"><a href="#section1">The rare earth elements</a></li>
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                    <li><a href="#section2">Wet Lab Work</a></li>
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                    <li><a href="#section3">Existing recovery technology</a></li>
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                    <li><a href="#section4">Rare Earth Enrichment<br>By Optimised Tools</a></li>
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                    <h3 style="background-color:#ce6b9a;color:#ffffff; padding:10px;letter-spacing:1px;margin-top:0;">The rare earth elements</h3>
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                    <p>The rare earth elements (REE) are a group of metals comprised of yttrium and fourteen lanthanide elements: lanthanum (La), cerium (Ce), praseodymium (Pr), neodymium (Nd), samarium (Sm), europium (Eu), gadolinium (Gd), terbium (Tb), dysprosium (Dy), holmium (Ho), erbium (Er), thulium (Tm), ytterbium (Yb), and lutetium (Lu). The REE are important in a growing number of critical technologies due to their unique physical and chemical properties<sup>[1]</sup>. Therefore, the REE are called “the Vitamin of Industry”. Besides, the output of REE  varies from country to country.
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                    <p class="col-xs-12">In China, especially in Jiangxi province, there’s a huge amount of mining and smelting plants. Because of the waste water from these factories cannot be treated well, the content of REE in the surrounding soils and crops increased at a high rate <sup>[2]</sup>. </p>
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                    <h3 style="background-color:#ce6b9a;color:#ffffff; padding:10px;letter-spacing:1px; margin-top:0;">The environmental problems</h3>
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                    <p>The rare earth elements (REE) may have an impact on soil、water and organism.</p>
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                    <p>When rare earth elements enters the soil, most of them will be absorbed by the soil, a small fraction of the remaining REEs exist in the soil as organic 、inorganic complexes and ionic state which can be absorbed and recycled directly. In this way, the rare earth elements will affect the amount of microorganism、the activity of the enzyme and the nutrients in the soil.</p>
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                    <p> There are two main kinds of rare earth elements in the water, one is being sucked by the organism, the other is transferred to the depositional phase. The rare earth elements in the water is mainly present in the suspended state, so they can’t migrate easily. Finally, they will exist in the deposited state which can be moved easily.</p>
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                    <p class="col-xs-12">  A certain amount of rare earth elements can inhibit the growth of animals and cause the pathological changes of the spleen 、liver and other visceral tissues. Besides, it can also affect the amount of rare earth elements in the internal organs. </p>
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                    <h3><span><strong>WHAT</strong></span> ARE WE WORKING ON ?</h3>
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                    <p> This year HUST-China focuses on the enrichment of rare earth elements. By designing and constructing the genetic circuits we can recycle the rare earth ions and purify waste water. Our final goal is to build a highly intelligent & efficient engineering circuit including specific peptides.</p>
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                    <h3 style="background-color:#ce6b9a;color:#ffffff; padding:10px;letter-spacing:1px; margin-top:0;">Existing recovery technology</h3>
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                    <p>While research on methods for recycling and recovering REEs from as early as 1984 was identified during our literature review, it is not until recently that more attention within industry and the literature has been given to the topic of REE recycling. The primary drivers for this renewed focus include the increased demand for REEs, concern about REE supplies, increasing cost of REEs, and new policies implemented by some countries mandating REE recycling for selected items.</p>
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                     <h3 style="background-color:#ce6b9a;color:#ffffff; padding:10px;letter-spacing:1px; margin-top:0;">Rare Earth Enrichment By Optimised Tools</h3>
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                     <h3><span><strong>WHY</strong></span> WE FOCUS ON THIS ?</h3>
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                     <p>This year we are going to design a bacteria—the REEBOT to gather REE from the wasted water from the factories. As we know that most of the REE are lanthanide, so we decide to use the most successful lanthanide binders that can selectively bind lanthanide ions with high affinities<sup>[3]</sup>. We try to make the bacteria express the LBTs intelligently to bind the lanthanide ions in the wasted water. </p>
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                     <p> The rare-earth elements (REE) has aroused more and more public attention due to the roles it plays in different fields—permanent magnets, catalysts, rechargeable batteries and other high tech products<sup>[1]</sup>. However, processes like mining, refining, and recycling of rare earth elements do serious harm to the environment if not properly managed. For instance, toxic acids are produced during the refining process and they are particular to be transfered into the general water supply<sup>[2]</sup>. So we want to figure out a way through which we can not only enrich rare earth elements, but also be environmentally friendly. That’s why we turn to synthetic biology to solve the environmental problem.</p>
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                    <p>The present in-situ leaching technology will destroy vegetation, and the electrolyte solution will be poured into the environment<sup>[4]</sup>. The bacteria we designed will bind the REE in the wasted water and then gather on the surface of the silicon—the si-tag we used in iGEM-HUST 2015—so it limited the bacteria’s expansion to keep safe. We can use this REE-bot to clear up the REE in the wasted water and recycle them and then reuse it in the industrial products. </p>
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                    <p> Through our work, we can reduce the pollution of rare earth elements to the water and meet the high demand of them in the market..We believe that it will be used well in the future.</p>
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                    <h3><span><strong>HOW</strong></span> WE ACHIEVE OUR GOAL ?</h3>
 +
                    <p> Our system has been divided into sensing part and capture part. We use lanthanide binding peptide and surface display system to recycle rare earth ions. The sensing part is based on the PmrA-B-C system which is discovered from salmonella. We also take 2015 HUST-China project as reference to help us recollect our bacterial. Further explanation will be shown in the description part.</p>
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                    <h3><span><strong>WHAT</strong></span> HAVE WE ACHIEVED ?</h3>
 +
                    <p> It was a memorable year that we recruited new team members in November 2016 and told the story of our project to the iGEMers all over the world in November 2017. iGEM was not only a litmus test that picked those who have a passion for synthetic biology, but also a window that gave us a chance to enjoy the charming scenery of synthetic biology. In the end, HUST-China won the Gold Medal with the efforts of all its team members.</p>
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             <h3><strong>References:</strong></h3>
+
             <h3><strong>Referrence:</strong></h3>
−
             <p>[1] Uncovering the end uses of the rare earth elements. Sci Total Environ. 2013 Sep 1;461-462 </p>
+
             <p>1.Binnemans K, Jones P T, Blanpain B, et al. Recycling of rare earths: a critical review[J]. Journal of Cleaner Production, 2013, 51(14):1–22.</p>
−
            <p>[2] Rare earth elements content in farmland soils and crops of the surrounding copper mining and smelting plant in Jiangxi province and evaluation of its ecological risk. Huan Jing Ke Xue. 2015 Mar;36(3):1060-8. </p>
+
             <p>2.Bradsher, Keith (October 29, 2010). "After China's Rare Earth Embargo, a New Calculus". The New York Times. Retrieved October 30, 2010.</p>
−
             <p>[3] Engineering Bacterial Two-Component System PmrA/PmrB to Sense Lanthanide Ions. J Am Chem Soc. 2013 Feb 13;135(6):2037-9</p>
+
−
            <p>[4] Present situation and application investigation of ion type rare earth mining technology in South China.</p>
+
−
            <p>Proceedings of Symposium on comprehensive utilization and environmental protection of rare earth resources, China, 2007
+
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            </p>
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             <h3><strong>Acknowledgments:</strong></h3>
 
             <h3><strong>Acknowledgments:</strong></h3>
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Latest revision as of 03:45, 16 December 2017

Team:HUST-China

demo1

WHAT ARE WE WORKING ON ?

This year HUST-China focuses on the enrichment of rare earth elements. By designing and constructing the genetic circuits we can recycle the rare earth ions and purify waste water. Our final goal is to build a highly intelligent & efficient engineering circuit including specific peptides.

demo1

WHY WE FOCUS ON THIS ?

The rare-earth elements (REE) has aroused more and more public attention due to the roles it plays in different fields—permanent magnets, catalysts, rechargeable batteries and other high tech products[1]. However, processes like mining, refining, and recycling of rare earth elements do serious harm to the environment if not properly managed. For instance, toxic acids are produced during the refining process and they are particular to be transfered into the general water supply[2]. So we want to figure out a way through which we can not only enrich rare earth elements, but also be environmentally friendly. That’s why we turn to synthetic biology to solve the environmental problem.

demo1

HOW WE ACHIEVE OUR GOAL ?

Our system has been divided into sensing part and capture part. We use lanthanide binding peptide and surface display system to recycle rare earth ions. The sensing part is based on the PmrA-B-C system which is discovered from salmonella. We also take 2015 HUST-China project as reference to help us recollect our bacterial. Further explanation will be shown in the description part.

demo1

WHAT HAVE WE ACHIEVED ?

It was a memorable year that we recruited new team members in November 2016 and told the story of our project to the iGEMers all over the world in November 2017. iGEM was not only a litmus test that picked those who have a passion for synthetic biology, but also a window that gave us a chance to enjoy the charming scenery of synthetic biology. In the end, HUST-China won the Gold Medal with the efforts of all its team members.

Referrence:

1.Binnemans K, Jones P T, Blanpain B, et al. Recycling of rare earths: a critical review[J]. Journal of Cleaner Production, 2013, 51(14):1–22.

2.Bradsher, Keith (October 29, 2010). "After China's Rare Earth Embargo, a New Calculus". The New York Times. Retrieved October 30, 2010.

Acknowledgments: