Difference between revisions of "Team:UCLouvain/Approach1"
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<span>Auxotrophe approach</span> | <span>Auxotrophe approach</span> | ||
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<div class="small-title montserrat-text uppercase">Photocaged ONB</div> | <div class="small-title montserrat-text uppercase">Photocaged ONB</div> | ||
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<p>Our aim is to create a rapid UV-response system, so people can be rapidly warned of an UV-exposure. For this reason, we’ve decided to work with a photocaged amino acid. One of our PIs, Professor Patrice Soumillon, has already worked with those compounds during his doctoral thesis and knows how efficiently they work. We’ve used the ortho-nitrobenzyl tyrosine (ONB-Tyr) for its relatively low price compared with other photocaged amino acids. The cage, the ONB molecule, is cleaved when exposed to UV rays, and releases the tyrosine for protein synthesis (Fig 1). </p> | <p>Our aim is to create a rapid UV-response system, so people can be rapidly warned of an UV-exposure. For this reason, we’ve decided to work with a photocaged amino acid. One of our PIs, Professor Patrice Soumillon, has already worked with those compounds during his doctoral thesis and knows how efficiently they work. We’ve used the ortho-nitrobenzyl tyrosine (ONB-Tyr) for its relatively low price compared with other photocaged amino acids. The cage, the ONB molecule, is cleaved when exposed to UV rays, and releases the tyrosine for protein synthesis (Fig 1). </p> | ||
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Revision as of 23:30, 30 October 2017
Our project
Auxotroph
Auxotrophe approach
Photocaged ONB
Our aim is to create a rapid UV-response system, so people can be rapidly warned of an UV-exposure. For this reason, we’ve decided to work with a photocaged amino acid. One of our PIs, Professor Patrice Soumillon, has already worked with those compounds during his doctoral thesis and knows how efficiently they work. We’ve used the ortho-nitrobenzyl tyrosine (ONB-Tyr) for its relatively low price compared with other photocaged amino acids. The cage, the ONB molecule, is cleaved when exposed to UV rays, and releases the tyrosine for protein synthesis (Fig 1).
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