Team:Hamburg/Biochemistry
Biochemistry
Nor-Pyochelin
Nor-Pyochelin is a chemical derivate of pyochelin, which lacks a single methyl group on its second cyclized cysteine residue. Based on the work of Abdallah et. al., which included a detailed analysis of pyochelin and a couple of similar compounds. We figured that Nor-Pyochelin would outcompete native pyochelin as a potential antibiotic carrier molecule since Abdallah et. Al. measured a 30% higher receptor affinity and iron transport capability for Nor-Pyochelin. An effect that we wanted to replicate in our antibiotic efficiency study.
