Team:IISc-Bangalore/HP/Gold Integrated

  1. Lupin Research Park
  2. FLOATeins
  3. Cell Separation
  4. Regulations

Lupin

Lupin is the seventh-largest biopharmaceutical company in the world by market capitalization, specializing in manufacturing biosimilars and therapeutics. Lupin Research Park — headquartered in Pune, India — hosts the R&D program and is home to over 1400 scientists who work on drug design, manufacturing and delivery. As part of our initiative to collaborate with industry and discover where gas vesicles' unique properties could be exploited, we contacted Lupin and requested a meeting with their Head of Downstream Processing to discuss our project ideas and potential applications.

On July XX, we entered Lupin's R&D facility — leaving all our electronics with security (making us unable to photographically document our journey) — to discover a whole new world... Held to industrial biosafety standards, Lupin's environment was spartan. Fire extinguishers, emergency exits, spill clean-up cabinets and personal protective equipment stands were prominently visible everywhere, emphasizing the importance of safety in such a pursuit.

After a short wait at reception, we were ushered to a conference room with the Head of Downstream Processing and a Principal Research Scientist who was our chaperone for the day. In that official setting, we pitched our project idea — iFLOAT 1.0 — to them and explained to them the features of gas vesicles that might make them attractive for industrial applications.

FLOATeins

Our initial idea — using gas vesicles for protein purification — was met with some skepticism. The cost of producing gas vesicles in bulk was raised.

Cell Separation

Regulations