Difference between revisions of "Team:Sydney Australia/Design"

Line 425: Line 425:
 
   border-radius: 5px;
 
   border-radius: 5px;
 
   background-clip: padding-box;
 
   background-clip: padding-box;
   padding:0 20px 20px 20px;
+
   padding:0 10px 10px 10px;
 
   min-height:300px;
 
   min-height:300px;
 
   min-width:200px
 
   min-width:200px
Line 451: Line 451:
 
   border-radius: 5px;
 
   border-radius: 5px;
 
   background-clip: padding-box;
 
   background-clip: padding-box;
 +
  padding:0 10px 10px 10px;
 
   min-height:300px;
 
   min-height:300px;
 
   min-width:200px
 
   min-width:200px

Revision as of 03:43, 9 October 2017

Our Key Goals

The aim of the USYD iGEM 2017 team was to address the problem of insulin inaccessibility. The design of our insulin, and its means of expression, needed to look at five key characteristics:

Stability

Which is worse, that everyone has his price, or that the price is always so low.

Single Chained

I'm killing time while I wait for life to shower me with meaning and happiness.

Affordable

I'm killing time while I wait for life to shower me with meaning and happiness.

Intellectual Property Issues

I'm killing time while I wait for life to shower me with meaning and happiness.

Safety and Efficacy

Which is worse, that everyone has his price, or that the price is always so low.

Our Constructs:

In order to meet off all of these characteristics, we decided to use Human insulin and develop our very own Single Chain Insulin. Though we would have preferred to have a single insulin that holds all of these characteristics, at this point in time there isn't a single insulin fully categorised that meets all of these criteria.

Proinsulin



Characterisation!

Sequence Length:

pI:

Sequence!

Winsulin



Characterisation!

Sequence Length:

pI:

Sequence!