Difference between revisions of "Team:ASIJ TOKYO"
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| − | + | <h1> Welcome to iGEM 2017! </h1> | |
| − | + | <p>Colorectal cancer remains the second most lethal cancer in the United States, often beginning as benign polyps in the colon and rectum. Despite relative ease of treatment, cases of CRC are usually detected in its late stages, rendering care difficult. CRC results from the mutation of multiple genes involved with the regulation of cell proliferation and DNA repair, with the ASIJ iGEM team focusing primarily on the Wnt pathway. The activation of the Wnt pathway specifically inhibits the degradation of beta-catenin, a protein that triggers the mutation of oncogenes and tumor suppressor gene. Through detection of these mutated genes and their subsequent downstream proteins, our team aims to develop an early screening method that can be adapted to a CRC detecting home-kit. Building off of a split-luciferase system characterized by the 2015 Peking iGEM team, our construct consists of a promoter reporter system that looks specifically at two downstream products, C-myc and COX-2. | |
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| − | + | <h5>Before you start: </h5> | |
| − | + | <p> Please read the following pages:</p> | |
| − | + | <ul> | |
| − | + | <li> <a href="https://2017.igem.org/Competition">Competition Hub</a> </li> | |
| − | + | <li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li> | |
| − | + | <li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li> | |
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| − | + | <h5> Styling your wiki </h5> | |
| − | + | <p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p> | |
| − | + | <p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p> | |
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| − | + | <h5> Wiki template information </h5> | |
| − | + | <p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p> | |
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| − | + | <h5> Editing your wiki </h5> | |
| − | + | <p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p> | |
| − | + | <p> <a href="https://2017.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p> | |
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| − | < | + | <h5>Tips</h5> |
| − | + | <p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p> | |
| − | </ | + | <ul> |
| + | <li>State your accomplishments! Tell people what you have achieved from the start. </li> | ||
| + | <li>Be clear about what you are doing and how you plan to do this.</li> | ||
| + | <li>You have a global audience! Consider the different backgrounds that your users come from.</li> | ||
| + | <li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li> | ||
| + | <li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li> | ||
| + | <li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li> | ||
| + | <li>Have lots of fun! </li> | ||
| + | </ul> | ||
| + | </div> | ||
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| + | <h5>Inspiration</h5> | ||
| + | <p> You can also view other team wikis for inspiration! Here are some examples:</p> | ||
| + | <ul> | ||
| + | <li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li> | ||
| + | <li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li> | ||
| + | <li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li> | ||
| + | <li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li> | ||
| + | <li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li> | ||
| + | <li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li> | ||
| + | </ul> | ||
| + | </div> | ||
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| + | <h5> Uploading pictures and files </h5> | ||
| + | <p> You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br /> | ||
| + | When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br> | ||
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| + | <a href="https://2017.igem.org/Special:Upload"> | ||
| + | UPLOAD FILES | ||
| + | </a> | ||
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Revision as of 02:54, 28 June 2017
ASIJ_TOKYO
Welcome to iGEM 2017!
Colorectal cancer remains the second most lethal cancer in the United States, often beginning as benign polyps in the colon and rectum. Despite relative ease of treatment, cases of CRC are usually detected in its late stages, rendering care difficult. CRC results from the mutation of multiple genes involved with the regulation of cell proliferation and DNA repair, with the ASIJ iGEM team focusing primarily on the Wnt pathway. The activation of the Wnt pathway specifically inhibits the degradation of beta-catenin, a protein that triggers the mutation of oncogenes and tumor suppressor gene. Through detection of these mutated genes and their subsequent downstream proteins, our team aims to develop an early screening method that can be adapted to a CRC detecting home-kit. Building off of a split-luciferase system characterized by the 2015 Peking iGEM team, our construct consists of a promoter reporter system that looks specifically at two downstream products, C-myc and COX-2.
Before you start:
Please read the following pages:
Styling your wiki
You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.
While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.
Wiki template information
We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!
Editing your wiki
On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!
Use WikiTools - Edit in the black menu bar to edit this page
Tips
This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:
- State your accomplishments! Tell people what you have achieved from the start.
- Be clear about what you are doing and how you plan to do this.
- You have a global audience! Consider the different backgrounds that your users come from.
- Make sure information is easy to find; nothing should be more than 3 clicks away.
- Avoid using very small fonts and low contrast colors; information should be easy to read.
- Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2017 calendar
- Have lots of fun!
Inspiration
You can also view other team wikis for inspiration! Here are some examples:
Uploading pictures and files
You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)
UPLOAD FILES
