Difference between revisions of "Team:Hong Kong-CUHK"

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            <a href="https://2014.igem.org/"><img src="https://static.igem.org/mediawiki/2014/0/09/Aalto_Helsinki_Logov_iGEM.png" class="img-responsive igem-logo"></a>
 
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<h1>Aalto-Helsinki<br>
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<small>Bioworks</small></h1>
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<img src="https://static.igem.org/mediawiki/2014/d/dc/Aalto_Helsinki_Logov_Oma.png" class="img-responsive omalogo center-block">
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Figuring out how to combine business with science.
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            <a href="#Abstract">
 
                Scroll down to read more
 
                <img src="https://static.igem.org/mediawiki/2014/3/3e/Aalto_Helsinki_Nuoli.png" class="img-responsive center-block transp nuoli">
 
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<div class="column full_size" >
            <a href="http://i-see-faces.deviantart.com/">Photo © Tanja Maria</a>
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<h1> Welcome to iGEM 2017! </h1>
        </p>
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<p>Your team has been approved and you are ready to start the iGEM season! Here is a link: <a href="http://igem.erg.cuhk.edu.hk">DR SWITCH</a></p>
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<h5>Before you start: </h5>
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<p> Please read the following pages:</p>
 +
<ul>
 +
<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
 +
<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
 +
<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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</ul>
 
</div>
 
</div>
<script src="https://2014.igem.org/Team:Aalto-Helsinki/jquery-1.11.0.min.js?action=raw&ctype=text/js"></script>
 
<article>
 
<div class="link" id="Abstract"></div>
 
<h2>Aalto-Helsinki Bioworks<br>
 
<small>A Synthetic Biology Startup with a Three-Channel Gene Switch</small></h2>
 
  
<h3>Project Description</h3>
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<p>
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<div class="highlight">
We have engineered a three-channel switch that is controlled with the intensity of blue light. By utilizing the mechanisms of the lambda repressor, we are able to switch between the expressions of three different genes with a short delay. This kind of mechanism provides a nearly real-time control over genes, which could provide advantages in variety of industrial bioprocesses.
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<h5> Styling your wiki </h5>
</p>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
<p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
Inspired by the principles of open source software, we introduce an Open Source business model implemented around our switch. We want to encourage future companies to create Open Source based solutions and to empower customers to participate in the product development. Open Source model’s transparency as well as lower degree of protection raises trust and continuity and benefits larger community.
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</div>
</p>
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</div>
<p>
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We want to share our experiences and insights in biotech entrepreneurship and address the difficulties that students and newcomers may face in the early stages of building a synthetic biology startup.
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</p>
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    <div class="row">
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        <div class="img-center">
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            <a href="http://youtu.be/tlc7MPY9SE8"><img src="https://static.igem.org/mediawiki/2014/7/79/Aaltohelsinki_pitc_capture.png" class="img-responsive smallerimg"></img></a>
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            <p class="kuvateksti">
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                Our pitch video on August 6th, Summer of Startups Demo Day.
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            </p>
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        </div>
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    </div>
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<img src="https://static.igem.org/mediawiki/2014/7/7e/Aalto_Helsinki_Logot_Oma.png" class="img-responsive center-block omalogot">
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</article>
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<div class="column full_size" >
<article class="abg-pcb">
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<div class="highlight">
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<h5> Wiki template information </h5>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
 +
</div>
 +
</div>  
  
<h2>The Story of Aalto-Helsinki Bioworks</h2>
 
<div class="row">
 
<div class="col-md-6 text-col-left">
 
<p>
 
We are Aalto-Helsinki Bioworks, the first-ever Finnish iGEM Team and one of the four teams in the new Entrepreneurship Track. Our <a href="https://2014.igem.org/Team:Aalto-Helsinki/Team">team</a> consists of nine students from Aalto University and the University of Helsinki and we are combining our interdisciplinary forces to develop something new and fascinating. We want to put Finland on the map of synthetic biology and improve undergraduate research opportunities in our universities.
 
</p>
 
<p>
 
We have <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research">designed</a> a three-channel gene switch that would make it possible to control three user-defined genes with blue light intensity. We are using <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research#yf1-title">YF1</a> as our light receptor protein and the signal is mediated to lambda repressor protein (CI) production via phosphorylation pathway. The concentration of the CI protein defines the gene that should be active at a time. The secret behind this function is our modified version of the <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research#lambda-title">lambda repressor</a> mechanism.
 
</p>
 
<p>
 
We constructed a mathematical <a href="https://2014.igem.org/Team:Aalto-Helsinki/Modeling">model</a> that simulates the interactions of the molecules and function of the gene switch we designed. This revealed interesting phenomena in the dynamics of our system which helps us to better understand the capabilities and limitations of the gene switch. We also made an <a href="http://igem-qsf.github.io/SimCircus/WebUI/">interactive simulation</a> available to everybody to best illustrate how our idea actually works.
 
</p>
 
<p>
 
To control the amount of blue light on our cell cultures, we created the <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research#ledrig-title">LED rig</a> device. This enabled us to perform diverse experiments in order to characterize our light response element. These <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research#Results">results</a> show that our light response element is able to regulate the downstream gene expression precisely. In addition, the response time is in a ten-minute-scale, which enables constant and nearly real-time control over bacterial cultures. In addition, we hypothesize that this system is also applicable to bioreactors, which would enable higher level of control in industrial bioprocesses. However, our fully functional prototype is still under ongoing development.
 
</p>
 
<p>
 
We have developed an open approach to <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business">biotech business</a> inspired by the business models for open source software. Following the Open Source philosophy, we will distribute open Aalto-Helsinki Bioworks technologies for free to everybody - as long as they share the improvements made on the technology. Therefore, we empower our users to participate in product development. Our <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business#canvas-title">business model</a> is based on hardware and wide range of services offered to our customers.
 
</p>
 
<p>
 
During the summer we participated in Aalto Entrepreneurship Society’s <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business#Sos">Summer of Startups 2014</a> incubator programme to learn the essential entrepreneurial skills, such as pitching, investor relations, customer-driven development and <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business#pitch-title">explaining</a> the science for general audience. See our Demo Day video for details.
 
</p>
 
<p>
 
iGEM is an international experience and as the first Finnish team, we went to find advice and experience around the globe. We contributed to the iGEM community by building a <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation#Seekers">BioBrick Seeker</a> tool which makes it easy to find parts of your interest in the 2014 BioBrick distribution. This tool has been used by iGEM teams all over the world! We also did a lot of <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation#Interteam">cooperation</a>, including filling out surveys and having skype conversations and live meetings with current and previous iGEM teams from France, Colombia, Switzerland, USA and the Netherlands. We even made a <a href="http://www.youtube.com/embed/icPgP3OOVOQ?rel=0">video</a> together with ETH Zürich team to Colombia team’s challenge.
 
</p>
 
<p>
 
We wanted to <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach">raise awareness</a> about synthetic biology in Finland and also showcase researchers’ work to young people and undergraduate students. Therefore, we have been reaching out to general public, especially young people via <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach#SoMe">social media</a>, including <a href="http://www.facebook.com/AaltoHelsinki">Facebook</a>, <a href="http://twitter.com/AaltoHelsinki">Twitter</a>, <a href="http://www.youtube.com/channel/UCEZliqjLu86CRpQlk57FfSw">Youtube</a>, <a href="http://www.flickr.com/photos/aaltohelsinki/">Flickr</a> and our own blog. We’ve shared stories, pictures, videos and experiences to our followers. In addition, we have been featured in radio interviews and articles on magazines and webzines. We also made a silly game: <a href="https://2014.igem.org/Team:Aalto-Helsinki/Flappycoli">Flappy Coli</a>. We have a public team webpage, <a href="http://2014.aaltohelsinki.com/">aaltohelsinki.com</a>, where you can find the latest stories of Aalto Helsinki also in the future. We lifted some of the highlights of this project on a <a href="https://2014.igem.org/Team:Aalto-Helsinki/Journal#Timeline">timeline</a>: the story of Aalto-Helsinki Bioworks is there for you to see!
 
</p>
 
</div>
 
<div class="col-md-6 img-100">
 
<img src="https://static.igem.org/mediawiki/2014/a/a2/Aalto_Helsinki_Banner.png" class="img-responsive">
 
</div>
 
</div>
 
  
 +
<div class="column full_size" >
 +
<h5> Introduction </h5>
 +
<div class="highlight">
 +
<p>This is the introduction. We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
 +
</div>
 +
</div>
  
</article>
 
<article>
 
  
<h2 class="kakspaddingbot">Accomplishments</h2>
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<div class="column half_size" >
<ul>
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<h5> Editing your wiki </h5>
<li>Best undergraduate wiki 2014</li>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
<li>Poster</li>
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<p> <a href="https://2017.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
<li>Presentation at the Giant Jamboree in Boston</li>
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<li>Background research, design and the creation of a <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research">Three-Channel Gene Switch</a></li>
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<li>Submission of <a href="https://2014.igem.org/Team:Aalto-Helsinki/Research#Parts">three new BioBricks and two new primers to the Registry</a></li>
+
<li>Creation of <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business#Plan">an Open Source business model and a business plan</a> for Synthetic Biology Entrepreneurship</li>
+
<li>Logo and brand design</li>
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<li><a href="http://youtu.be/tlc7MPY9SE8">Pitch</a> to an audience of 1000+ people</li>
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<li>Participation in the <a href="https://2014.igem.org/Team:Aalto-Helsinki/Business#Sos">Summer of Startups</a>, a startup incubator program</li>
+
<li>Connecting with <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach">investors and general public</a></li>
+
<li>Received 45 000€ in <a href="https://2014.igem.org/Team:Aalto-Helsinki/Team#Sponsors">funding</a></li>
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<li>Drawing attention <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach#Media">in the media</a></li>
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<li>BioBrick and Team <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation#Seekers">Seekers</a></li>
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<li>Collaboration with other <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation#Interteam">iGEM teams</a></li>
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<li>Participation in the <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation#Interlab">Measurement Interlab Study</a></li>
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</ul>
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</article>
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</div>
<article>
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<h2>Categories</h2>
 
  
<p>
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<div class="column half_size" >
Our wiki has seven different categories in addition to this main page. On each of them you can just scroll through the content until you're finished reading. Everything about the subject can be found on one page, additional material is provided when possible and pages discussing similar topics are linked to each other. A submenu will also appear when you start scrolling through the other pages: see the top of the page as you advance in the wiki!
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<h5>Tips</h5>
</p>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
<div class="row row-eq-height">
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<ul>
<div class="col-md-4 bg feat feat-left bg-team">
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
<a href="https://2014.igem.org/Team:Aalto-Helsinki/Team">
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<li>Be clear about what you are doing and how you plan to do this.</li>
<div class="feattext-container-tall">
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
  <div class ="feattext-cell">
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
<p class="feattext-p">
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li>
<big><big><big>Team</big></big></big><br>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li>
We are a team of nine Finnish students and we've gotten amazing support during this project.
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<li>Have lots of fun! </li>
</p>
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</ul>  
</div>
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</div>
</div>
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</a>
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</div>
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<div class="col-md-4 bg feat feat-center bg-business">
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<a href="https://2014.igem.org/Team:Aalto-Helsinki/Business">
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<div class="feattext-container-tall">
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  <div class ="feattext-cell">
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<p class="feattext-p">
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<big><big><big>Business</big></big></big><br>
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We explored the possibilities of biotech and synthetic biology business.
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</p>
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</div>
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</div>
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</a>
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</div>
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<div class="col-md-4 bg feat feat-right bg-research">
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<a href="https://2014.igem.org/Team:Aalto-Helsinki/Research">
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<div class="feattext-container-tall">
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  <div class ="feattext-cell">
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<p class="feattext-p">
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<big><big><big>Research</big></big></big><br>
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We engineered a three-channel switch that can be controlled with the intensity of blue light.
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</p>
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</div>
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</div>
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</a>
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</div>
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</div>
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<div class="row row-eq-height">
 
<div class="col-md-6 bg feat feat-left bg-modeling">
 
<a href="https://2014.igem.org/Team:Aalto-Helsinki/Modeling">
 
<div class="feattext-container-tall">
 
  <div class ="feattext-cell">
 
<p class="feattext-p">
 
<big><big><big>Modeling</big></big></big><br>
 
We made mathematic models of the interactions behind our gene switch.
 
</p>
 
</div>
 
</div>
 
</a>
 
</div>
 
<div class="col-md-6 bg feat feat-right bg-cooperation">
 
<a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation">
 
<div class="feattext-container-tall">
 
  <div class ="feattext-cell">
 
<p class="feattext-p">
 
<big><big><big>Cooperation</big></big></big><br>
 
We got to know other iGEM teams and developed tools for everyone to use.
 
</p>
 
</div>
 
</div>
 
</a>
 
</div>
 
</div>
 
<div class="row row-eq-height">
 
<div class="col-md-6 bg feat feat-left bg-outreach">
 
<a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach">
 
<div class="feattext-container-tall">
 
  <div class ="feattext-cell">
 
<p class="feattext-p">
 
<big><big><big>Outreach</big></big></big><br>
 
We spread the word about iGEM and synthetic biology especially in Finland.
 
</p>
 
</div>
 
</div>
 
</a>
 
</div>
 
<div class="col-md-6 bg feat feat-right bg-journal">
 
<a href="https://2014.igem.org/Team:Aalto-Helsinki/Journal">
 
<div class="feattext-container-tall">
 
  <div class ="feattext-cell">
 
<p class="feattext-p">
 
<big><big><big>Journal</big></big></big><br>
 
We documented the project well.
 
</p>
 
</div>
 
</div>
 
</a>
 
</div>
 
</div>
 
<div class="cpright">
 
<p class ="kuvateksti">
 
<a href="http://i-see-faces.deviantart.com/">Photos © Tanja Maria</a>
 
</p>
 
</div>
 
<p>
 
If you find yourself lost (or simply don't know where to start looking for what you'd want to find), <a href="https://static.igem.org/mediawiki/2014/7/73/Aalto_Helsinki_Wiki_Sitemap.png" target="_blank">here's a sitemap to help with the task</a>!
 
</p>
 
  
</article>
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<div class="column half_size" >
 +
<h5>Inspiration</h5>
 +
<p> You can also view other team wikis for inspiration! Here are some examples:</p>
 +
<ul>
 +
<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
 +
<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
 +
<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
 +
<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
 +
<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
 +
<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
 +
</ul>
 
</div>
 
</div>
</body>
 
<script>
 
$(document).ready(function() {
 
  
if(location.pathname != "/Team:Aalto-Helsinki") {
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<div class="column half_size" >
$('#navigation a[href^="https://2014.igem.org' + location.pathname + '"]').addClass('active');
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<h5> Uploading pictures and files </h5>
} else $('#navigation a.home').addClass('active');
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<p> You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
});
+
When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br>
</script>
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<script type="text/javascript">
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<a href="https://2017.igem.org/Special:Upload">
    // Picture reference script
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UPLOAD FILES
    /*
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</a>
    USAGE:
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</p>
    tag img with a ref that is connected to the image, such as:
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</div>
    <img src="aaltohelsinki.com/testikuva.png" ref="varioskan" />
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    When you insert a reference in text, put a tag with a ref attribute:
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    <a ref="varioskan"></a>
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    Do not put href attribute, it will be replaced with a link to the image.
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    Moreover, inner html of the anchor tag will be "figure x" where x is the
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    correct figure number. If span or anchor has "." as the inner html, the
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    caption will be capitalized.
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    */
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    var images = $('img[ref]');
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    $.each(images, function(index, e){
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            var referenceName = e.getAttribute("ref");
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            if (!e.id){
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                e.setAttribute("id","figure"+(index+1));
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            }
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            $.each($('a[ref="'+referenceName+'"]'), function(j, e2){
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                e2.setAttribute("href","#"+e.id);
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                if (e2.innerHTML == "."){
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                    e2.innerHTML = "Figure " + (index+1);
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                } else {
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                    e2.innerHTML = "figure " + (index+1);
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                }
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            });
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            $.each($('span[ref="'+referenceName+'"]'), function(j, e2){
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                e2.setAttribute("href","#"+e.id);
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                if (e2.innerHTML == "."){
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                    e2.innerHTML = "Figure " + (index+1);
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                } else {
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                    e2.innerHTML = "figure " + (index+1);
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                }
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            });
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        }
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    );
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    // Table reference script
 
    /*
 
    USAGE:
 
    tag table with a tab that is connected to the table, such as:
 
    <table ref="intensities" />
 
    When you insert a reference in text, put a tag with a ref attribute:
 
    <a tab="intensities"></a>
 
    Do not put href attribute, it will be replaced with a link to the image.
 
    Moreover, inner html of the anchor tag will be "table x" where x is the
 
    correct table number. If span or anchor has "." as the inner html, the
 
    caption will be capitalized.
 
    */
 
    var tables = $('table[tab], img[tab]');
 
    $.each(tables, function(index, e){
 
            var tableName = e.getAttribute("tab");
 
            if (!e.id){
 
                e.setAttribute("id","table"+(index+1));
 
            }
 
            $.each($('a[tab="'+tableName+'"]'), function(j, e2){
 
                e2.setAttribute("href","#"+e.id);
 
                if (e2.innerHTML == "."){
 
                    e2.innerHTML = "Table " + (index+1);
 
                } else {
 
                    e2.innerHTML = "table " + (index+1);
 
                }
 
            });
 
            $.each($('span[tab="'+tableName+'"]'), function(j, e2){
 
                e2.setAttribute("href","#"+e.id);
 
                if (e2.innerHTML == "."){
 
                    e2.innerHTML = "Table " + (index+1);
 
                } else {
 
                    e2.innerHTML = "table " + (index+1);
 
                }
 
            });
 
        }
 
    );
 
</script>
 
 
</html>
 
</html>
{{:Team:Aalto-Helsinki/footer}}
 

Revision as of 07:15, 13 May 2017

Welcome to iGEM 2017!

Your team has been approved and you are ready to start the iGEM season! Here is a link: DR SWITCH

Before you start:

Please read the following pages:

Styling your wiki

You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.

While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.

Wiki template information

We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Introduction

This is the introduction. We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Editing your wiki

On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!

Use WikiTools - Edit in the black menu bar to edit this page

Tips

This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:

  • State your accomplishments! Tell people what you have achieved from the start.
  • Be clear about what you are doing and how you plan to do this.
  • You have a global audience! Consider the different backgrounds that your users come from.
  • Make sure information is easy to find; nothing should be more than 3 clicks away.
  • Avoid using very small fonts and low contrast colors; information should be easy to read.
  • Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2017 calendar
  • Have lots of fun!
Inspiration

You can also view other team wikis for inspiration! Here are some examples:

Uploading pictures and files

You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to
T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)

UPLOAD FILES