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<h1> Welcome to HD Resolution's iGEM page! </h1>
 
<h1> Welcome to HD Resolution's iGEM page! </h1>
<p> We are a New York-based team working to find the cure to Huntington's Disease!
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<p> We are a New York-based team working to find the cure to Huntington's Disease! </p>
  
Huntington's disease (HD) is an autosomal dominant genetic disorder that causes the breakdown of nerve cells in the brain and currently has no cure, which is why we’re aiming to find one! HD, which is usually adult-onset, is particularly devastating because it includes symptoms such as amnesia, involuntary movements, and physical incoordination, usually giving a patient a lifespan of only ten years after onset. The primary cause of this disease is a trinucleotide repeat of CAG in the huntingtin gene, where a repeat of 40 or more can cause the manifestation of the disease. Our goal is to create a synthetic RNA strand displacement technology that consists of the corrected RNA strand and a “guide” strand. The guide strand will bond with endogenous, faulty messenger RNA and release the corrected RNA strand for proper protein synthesis of the huntingtin protein, while disposing of the repeating CAG sequence. Ultimately, once such technologies are developed to overcome endocytosis and blood brain barrier traversal, an injectable cure can be produced. Wish us luck!</p>
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Revision as of 03:26, 1 July 2017

Welcome to HD Resolution's iGEM page!

We are a New York-based team working to find the cure to Huntington's Disease!

Before you start:

Please read the following pages:

Styling your wiki

You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.

While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.

Wiki template information

We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Editing your wiki

On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!

Use WikiTools - Edit in the black menu bar to edit this page

Tips

This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:

  • State your accomplishments! Tell people what you have achieved from the start.
  • Be clear about what you are doing and how you plan to do this.
  • You have a global audience! Consider the different backgrounds that your users come from.
  • Make sure information is easy to find; nothing should be more than 3 clicks away.
  • Avoid using very small fonts and low contrast colors; information should be easy to read.
  • Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2017 calendar
  • Have lots of fun!
Inspiration

You can also view other team wikis for inspiration! Here are some examples:

Uploading pictures and files

You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to
T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)

UPLOAD FILES