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<td align="justify"><p style="margin-left:30px;"><b>Abstract </b><br>In our first approach, we utilize the DNA-binding function of deadCas9 (dCas9) to bind two enzymes of the Indoleacetic acid (IAA) pathway on a DNA-scaffold, which we introduce into E.coli. By binding the enzymes on DNA, we decrease the distance the substrates have to travel in the cytoplasm and thereby hope to achieve a higher output of Indoleacetic acid....<br><a href="https://2017.igem.org/Http://2017.igem.org/2017.igem.org/Team:Potsdam/Abstract">Find out more</a></p></td> | <td align="justify"><p style="margin-left:30px;"><b>Abstract </b><br>In our first approach, we utilize the DNA-binding function of deadCas9 (dCas9) to bind two enzymes of the Indoleacetic acid (IAA) pathway on a DNA-scaffold, which we introduce into E.coli. By binding the enzymes on DNA, we decrease the distance the substrates have to travel in the cytoplasm and thereby hope to achieve a higher output of Indoleacetic acid....<br><a href="https://2017.igem.org/Http://2017.igem.org/2017.igem.org/Team:Potsdam/Abstract">Find out more</a></p></td> | ||
− | <td align="justify"><p style="margin-left:30px;"><b>Project Design </b><br>Biotechnological applications have skyrocketed and evolved to be one of the most ubiquitous aspects in our daily life in the past years. From uses in food industry to dietary supplements and science, so-called white biotechnology is everywhere. | + | <td align="justify"><p style="margin-left:30px;"><b>Project Design </b><br>Biotechnological applications have skyrocketed and evolved to be one of the most ubiquitous aspects in our daily life in the past years. From uses in food industry to dietary supplements and science, so-called white biotechnology is everywhere. That’s why we try to recreate a widespread phenomenon called metabolic channelling synthetically and increase the yield in biochemical... <br> <a href="https://2017.igem.org/wiki/index.php?title=Team%3APotsdam%2FDesign">Find out more </p></td> |
− | That’s why we try to recreate a widespread phenomenon called metabolic channelling synthetically and increase the yield in biochemical... <br> <a href="https://2017.igem.org/wiki/index.php?title=Team%3APotsdam%2FDesign">Find out more </p></td> | + | |
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Revision as of 13:45, 1 November 2017
Background facts and information The field of synthetic biology combines different disciplines, like molecular biology, engineering, mathematics and physics to improve the knowledge of existing biological systems or to design and manipulate genes, pathways and entire genomes of organisms, for them to fulfill a certain purpose. Synthetic Biology is applied in various fields and disciplines. For biomedical applications it can be used to design ... Find out more |
Abstract |
Project Design |
Research work & Protocols Finding a suitable topic was very challenging and time consuming. Initially, we looked through projects of prior teams and assembled a list of possible topics. A big influence was a new method for assembling genes in a manufacturing manner which was being developed by a research group on our university. Based on the quick and easy synthesis of proteins a first idea was the creation of enzymes that could convert blood groups.... Find out more |
Modelling |
Labbook |
Main sponsors: