Team:Sydney Australia/Design
Our Key Goals
The aim of the USYD iGEM 2017 team was to address the problem of insulin inaccessibility. The design of our insulin, and its means of expression, needed to look at five key characteristics:
Stability
Which is worse, that everyone has his price, or that the price is always so low.
Single Chained
I'm killing time while I wait for life to shower me with meaning and happiness.
Affordable
I'm killing time while I wait for life to shower me with meaning and happiness.
Intellectual Property Issues
I'm killing time while I wait for life to shower me with meaning and happiness.
Safety and Efficacy
Which is worse, that everyone has his price, or that the price is always so low.
Our Constructs:
In order to meet off all of these characteristics, we decided to use Human insulin and develop our very own Single Chain Insulin. Though we would have preferred to have a single insulin that holds all of these characteristics, at this point in time there isn't a single insulin fully categorised that meets all of these criteria.
Proinsulin
Characterisation!
Sequence Length:
pI:
Sequence!
Winsulin
Characterisation!
Sequence Length:
pI:
Sequence!
