In today's world, despite the sophisticated food processing techniques right from the farm to a plate, food spoilage is a global concern. The volume of food wastage across the globe is estimated at 1.3 billion tonnes per year, out of which microbial spoilage stands at a substantial amount. In light of this, our team is working by utilizing synthetic biology approaches to produce an antimicrobial peptide called M-zodatoxin. Commonly known as Latarcin, it is a short linear cytolytic peptide found in spider venom. Via a carpet mechanism, this peptide alters the microbial metabolism. Herein we propose that this peptide can be incorporated to food packaging material in an attempt to safeguard the food from microbial contamination.