Difference between revisions of "Team:ColumbiaNYC"

Line 1: Line 1:
 +
<!DOCTYPE html>
 +
<html lang="en" dir="ltr" class="client-nojs">
 +
<head>
 +
<meta charset="UTF-8" />
 +
<title>Team:TAS Taipei - 2015.igem.org</title>
 +
<meta name="generator" content="MediaWiki 1.24.1" />
 +
<link rel="shortcut icon" href="/favicon.ico" />
 +
<link rel="search" type="application/opensearchdescription+xml" href="/wiki/opensearch_desc.php" title="2015.igem.org (en)" />
 +
<link rel="EditURI" type="application/rsd+xml" href="https://2015.igem.org/wiki/api.php?action=rsd" />
 +
<link rel="alternate" hreflang="x-default" href="/Team:TAS_Taipei" />
 +
<link rel="copyright" href="http://creativecommons.org/licenses/by/3.0/" />
 +
<link rel="alternate" type="application/atom+xml" title="2015.igem.org Atom feed" href="/wiki/index.php?title=Special:RecentChanges&amp;feed=atom" />
 +
<link rel="stylesheet" href="https://2015.igem.org/wiki/load.php?debug=false&amp;lang=en&amp;modules=mediawiki.legacy.commonPrint%2Cshared%7Cmediawiki.skinning.content.externallinks%7Cmediawiki.skinning.interface%7Cmediawiki.ui.button%7Cskins.igem.styles&amp;only=styles&amp;skin=igem&amp;*" />
 +
<!--[if IE 6]><link rel="stylesheet" href="/wiki/skins/Igem/IE60Fixes.css?303" media="screen" /><![endif]-->
 +
<!--[if IE 7]><link rel="stylesheet" href="/wiki/skins/Igem/IE70Fixes.css?303" media="screen" /><![endif]--><meta name="ResourceLoaderDynamicStyles" content="" />
 +
<style>a:lang(ar),a:lang(kk-arab),a:lang(mzn),a:lang(ps),a:lang(ur){text-decoration:none}
 +
/* cache key: 2015_igem_org:resourceloader:filter:minify-css:7:875d2068ffef0b9ce1dbab8400ce2379 */</style>
 +
<script src="https://2015.igem.org/wiki/load.php?debug=false&amp;lang=en&amp;modules=startup&amp;only=scripts&amp;skin=igem&amp;*"></script>
 +
<script>if(window.mw){
 +
mw.config.set({"wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"Team:TAS_Taipei","wgTitle":"Team:TAS Taipei","wgCurRevisionId":412354,"wgRevisionId":412354,"wgArticleId":1828,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":[],"wgBreakFrames":false,"wgPageContentLanguage":"en","wgPageContentModel":"wikitext","wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"dmy","wgMonthNames":["","January","February","March","April","May","June","July","August","September","October","November","December"],"wgMonthNamesShort":["","Jan","Feb","Mar","Apr","May","Jun","Jul","Aug","Sep","Oct","Nov","Dec"],"wgRelevantPageName":"Team:TAS_Taipei","wgIsProbablyEditable":false,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgWikiEditorEnabledModules":{"toolbar":false,"dialogs":false,"hidesig":true,"preview":false,"previewDialog":false,"publish":false}});
 +
}</script><script>if(window.mw){
 +
mw.loader.implement("user.options",function($,jQuery){mw.user.options.set({"ccmeonemails":0,"cols":80,"date":"default","diffonly":0,"disablemail":0,"editfont":"default","editondblclick":0,"editsectiononrightclick":0,"enotifminoredits":0,"enotifrevealaddr":0,"enotifusertalkpages":1,"enotifwatchlistpages":1,"extendwatchlist":0,"fancysig":0,"forceeditsummary":0,"gender":"unknown","hideminor":0,"hidepatrolled":0,"imagesize":2,"math":1,"minordefault":0,"newpageshidepatrolled":0,"nickname":"","norollbackdiff":0,"numberheadings":0,"previewonfirst":0,"previewontop":1,"rcdays":7,"rclimit":50,"rows":25,"showhiddencats":0,"shownumberswatching":1,"showtoolbar":1,"skin":"igem","stubthreshold":0,"thumbsize":5,"underline":2,"uselivepreview":0,"usenewrc":1,"watchcreations":1,"watchdefault":1,"watchdeletion":0,"watchlistdays":3,"watchlisthideanons":0,"watchlisthidebots":0,"watchlisthideliu":0,"watchlisthideminor":0,"watchlisthideown":0,"watchlisthidepatrolled":0,"watchmoves":0,"watchrollback":0,
 +
"wllimit":250,"useeditwarning":1,"prefershttps":1,"language":"en","variant-gan":"gan","variant-iu":"iu","variant-kk":"kk","variant-ku":"ku","variant-shi":"shi","variant-sr":"sr","variant-tg":"tg","variant-uz":"uz","variant-zh":"zh","searchNs0":true,"searchNs1":false,"searchNs2":false,"searchNs3":false,"searchNs4":false,"searchNs5":false,"searchNs6":false,"searchNs7":false,"searchNs8":false,"searchNs9":false,"searchNs10":false,"searchNs11":false,"searchNs12":false,"searchNs13":false,"searchNs14":false,"searchNs15":false,"variant":"en"});},{},{});mw.loader.implement("user.tokens",function($,jQuery){mw.user.tokens.set({"editToken":"+\\","patrolToken":"+\\","watchToken":"+\\"});},{},{});
 +
/* cache key: 2015_igem_org:resourceloader:filter:minify-js:7:c2a6e0f393444edcfe542f485c3692c2 */
 +
}</script>
 +
<script>if(window.mw){
 +
mw.loader.load(["mediawiki.page.startup","mediawiki.legacy.wikibits","mediawiki.legacy.ajax"]);
 +
}</script>
 +
</head>
 +
<body class="mediawiki ltr sitedir-ltr ns-0 ns-subject page-Team_TAS_Taipei skin-igem action-view">
 +
 +
        <script type='text/javascript'        src ='/common/tablesorter/jquery.tablesorter.min.js'></script>
 +
        <link rel='stylesheet' type='text/css' href='/common/tablesorter/themes/groupparts/style.css' />
 +
        <link rel='stylesheet' type='text/css' href='/common/table_styles.css' />
 +
 +
    <div id='globalWrapper'>
 +
        <div id='top_menu_under' class='noprint'></div>
 +
        <div id='top_menu_14' class='noprint'>Loading menubar.....</div> <!-- Will be replaced with the jQuery.load -->
 +
<script>jQuery('#top_menu_14').load('https://2015.igem.org/cgi/top_menu_14/menubar_reply.cgi',
 +
    {  t:"Team%3ATAS%20Taipei",
 +
a:"View+%2FTeam%3ATAS_Taipei++View source+%2Fwiki%2Findex.php%3Ftitle%3DTeam%3ATAS_Taipei%26action%3Dedit++History+%2Fwiki%2Findex.php%3Ftitle%3DTeam%3ATAS_Taipei%26action%3Dhistory++Page+%2FTeam%3ATAS_Taipei++Discussion+%2Fwiki%2Findex.php%3Ftitle%3DTalk%3ATeam%3ATAS_Taipei%26action%3Dedit%26redlink%3D1++" });
 +
 +
</script>
 +
<div id="content" class="mw-body" role="main">
 +
    <a id="top"></a>
 +
    <h1 id="firstHeading" class="firstHeading">
 +
        <span dir="auto">Team:TAS Taipei</span>
 +
    </h1>
 +
    <div id="bodyContent">
 +
<div id="mw-content-text" lang="en" dir="ltr" class="mw-content-ltr"><p>
 +
 +
<head>
 +
<title>TAS Taipei iGEM Wiki</title>
 +
<link rel="shortcut icon" href="https://static.igem.org/mediawiki/2014hs/2/2f/Tas_igemlogo.png">
 +
<link href='http://fonts.googleapis.com/css?family=Lato' rel='stylesheet' type='text/css'>
 +
<link rel="stylesheet" href="https://2015.igem.org/Template:TAS_Taipei/css/compiled?action=raw&amp;ctype=text/css">
 +
<link rel="stylesheet" href="https://2015.igem.org/Template:TAS_Taipei/css/bootstrap?action=raw&amp;ctype=text/css">
 +
 +
<script>localStorage.clear();</script>
 +
<script src="https://2015.igem.org/Template:TAS_Taipei/js/jquery?action=raw&amp;ctype=text/javascript"></script>
 +
<script src='https://2015.igem.org/Template:TAS_Taipei/js/bootstrap?action=raw&amp;ctype=text/javascript'></script>
 +
<script src="https://2015.igem.org/Template:TAS_Taipei/js/jquerySlides?action=raw&amp;ctype=text/javascript"></script>
 +
 +
 +
 +
<script>
 +
$(document).ready(function() {
 +
if(document.domain === "2015.igem.org")
 +
setTimeout(function() {
 +
$("style:eq(0)").remove();
 +
}, 500);
 +
});
 +
</script>
 +
</head>
 +
 +
 +
<body style = "text-align:center">
 +
<div class="container" style='z-index:10;position:relative;padding:0px'>
 +
<div class="row center-block" style = "text-align: left;">
 +
<nav style='font-family:Lato;font-size:22px;background-color:#2196f3;-webkit-transform: translateZ(0);z-index: 100;position: fixed;box-shadow: 0px 0px 10px black;'>
 +
<ul style='margin-left:0px'>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/project"><h4 class="dropdown-toggle disabled" data-toggle="dropdown"><b>PROJECT</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/project#background">Background</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/project/achievements">Achievements</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Collaborations">Collaborations</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Parts">Parts</a></h5>
 +
</div>
 +
</div>
 +
<div style='height:140px;'>
 +
<img src="https://static.igem.org/mediawiki/2015/5/5b/Tas_icon_project.png">
 +
<h4><b>Granzyme B</b> - a blessing and a curse. It's crucial for controlling cancer, but it causes damage when out of cellular space. Let's find the best of both worlds with <b>selective GzmB Inhibition.</b></h4>
 +
</div>
 +
 +
</div>
 +
</li>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/wetlab"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>EXPERIMENTAL</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/wetlab#construct">Granzyme Inhibitor Construct</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/wetlab#prototype">Prototype Work</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/wetlab#safety">Safety Switch</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Notebook">Notebook</a></h5>
 +
</div>
 +
</div>
 +
<div style='height:140px;'>
 +
<img src="https://static.igem.org/mediawiki/2015/f/f8/Tas_icon_wetlab.png">
 +
<h4>We conduct science - and we are proud to show it. Follow along with our journey of discovery in the lab.</h4>
 +
</div>
 +
</div>
 +
</li>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/Modeling"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>MODELING</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Modeling#serpin">SerpinA3N vs. GZMB</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Modeling#act">ACT3m vs. GZMB</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Modeling#analysis">Analysis</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Modeling#calculator">Calculator</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Modeling#flux">Flux Model</a></h5>
 +
</div>
 +
</div>
 +
<div style='height:140px;'>
 +
<img src="https://static.igem.org/mediawiki/2015/3/3e/Tas_icon_modeling.png">
 +
<h4>The power of <b>Math and Computation</b> provides us with valuable models and information. Find out how.</h4>
 +
</div>
 +
</div>
 +
</li>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/Practices"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>HUMAN PRACTICE</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Practices#research">Research</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Practices#change">Change</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Practices#outreach">Outreach</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Practices#entertainment">Entertainment</a></h5>
 +
</div>
 +
</div>
 +
<div style='height:140px;'>
 +
<img src="https://static.igem.org/mediawiki/2015/0/0f/Tas_icon_hp.png">
 +
<h4>We want to develop <b>socially concious solutions</b> - one that can be provided to all that need aid. Find out how we tackled <b>social aspects</b> of this project.</h4>
 +
</div>
 +
</div>
 +
</li>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/Safety"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>BIOSAFETY</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div style='height:100px;'>
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Safety#researcher_safety">Researcher Safety</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Safety#environmental_safety">Environmental Safety</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Safety#biobrick_safety">Biobrick Safety</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Safety#local_safety">Local Safety</a></h5>
 +
</div>
 +
</div>
 +
<img src="https://static.igem.org/mediawiki/2015/9/91/Tas_icon_safety.png">
 +
<h4><b>Safety first.</b> Especially in a lab. Here's how we maintained and investigated the integrity and security of our work environment.</h4>
 +
</div>
 +
</div>
 +
</li>
 +
<li class="dropdown">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei/team"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>TEAM</b></h4></a>
 +
<div class="dropdown-menu">
 +
<div class='subcategories_container'>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/team#members">Members</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/team#tas">About</a></h5>
 +
</div>
 +
<div>
 +
<h5><a href="https://2015.igem.org/Team:TAS_Taipei/Attributions">Attributions</a></h5>
 +
</div>
 +
</div>
 +
<div style='height:140px;'>
 +
<img src="https://static.igem.org/mediawiki/2015/3/34/Tas_icon_team.png">
 +
<h4>Behind every tough iGem project lies a tough, hard-working yet cheerful group of students. <b>Meet the team!</b></h4>
 +
</div>
 +
</div>
 +
</li>
 +
</ul>
 +
</nav>
 +
</div>
 +
<br>
 +
<br>
 +
<br>
 +
<div class="row center-block" style = "padding:10px;width:960px;background-color:#FFC107;box-shadow:0px 0px 5px black">
 +
<div class="row" style = "text-align:center;">
 +
<div class="col-sm-2">
 +
<a href="https://2015.igem.org/Team:TAS_Taipei" style='text-decoration: none'><img src="https://static.igem.org/mediawiki/2015/2/2f/Tas_igemlogo.png
 +
" alt="" style="width: 100px;"></a>
 +
</div>
 +
<div class="col-sm-8" style='text-align:center;'>
 +
<a href="https://2015.igem.org/Team:TAS_Taipei" style='text-decoration: none;'>
 +
<h2 style="font-family:'Lato';letter-spacing:10px;color: white; font-size: 60px;  margin-top: 0;  margin-bottom: 0;"><b>
 +
<img style = "height:64px;vertical-align:top" src = "https://static.igem.org/mediawiki/2015/5/5b/Tas_icon_project.png">RANZYME B</b></h2>
 +
</a>
 +
</div>
 +
<div class="col-sm-2">
 +
<a href="https://igem.org/HS"><img src="https://static.igem.org/mediawiki/2015/e/eb/Tas_igemlogo2.png" alt="" style="width: 100px;"></a>
 +
</div>
 +
</div>
 +
</div>
 +
 +
<script type="text/javascript" src="https://2015.igem.org/Template:TAS_Taipei/js/jssor?action=raw&amp;ctype=text/javascript"></script>
 +
<script type="text/javascript" src="https://2015.igem.org/Template:TAS_Taipei/js/jssorSlider?action=raw&amp;ctype=text/javascript"></script>
 +
 +
<br>
 +
<script>
 +
jQuery(document).ready(function ($) {
 +
var _CaptionTransitions = [];
 +
_CaptionTransitions["L"] = { $Duration: 800, x: 0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["R"] = { $Duration: 800, x: -0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["T"] = { $Duration: 800, y: 0.6, $Easing: { $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["B"] = { $Duration: 800, y: -0.6, $Easing: { $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["TL"] = { $Duration: 800, x: 0.6, y: 0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine, $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["TR"] = { $Duration: 800, x: -0.6, y: 0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine, $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["BL"] = { $Duration: 800, x: 0.6, y: -0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine, $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
_CaptionTransitions["BR"] = { $Duration: 800, x: -0.6, y: -0.6, $Easing: { $Left: $JssorEasing$.$EaseInOutSine, $Top: $JssorEasing$.$EaseInOutSine }, $Opacity: 2 };
 +
 +
_CaptionTransitions["WAVE|L"] = { $Duration: 1500, x: 0.6, y: 0.3, $Easing: { $Left: $JssorEasing$.$EaseLinear, $Top: $JssorEasing$.$EaseInWave }, $Opacity: 2, $Round: { $Top: 2.5} };
 +
_CaptionTransitions["MCLIP|B"] = { $Duration: 600, $Clip: 8, $Move: true, $Easing: $JssorEasing$.$EaseOutExpo };
 +
var options = {
 +
$AutoPlay: true,
 +
                    $AutoPlayInterval: 10000,
 +
$SlideDuration: 500, 
 +
                $DragOrientation: 3,                                //[Optional] Orientation to drag slide, 0 no drag, 1 horizental, 2 vertical, 3 either, default value is 1 (Note that the $DragOrientation should be the same as $PlayOrientation when $DisplayPieces is greater than 1, or parking position is not 0)
 +
 +
                $BulletNavigatorOptions: {                                //[Optional] Options to specify and enable navigator or not
 +
                    $Class: $JssorBulletNavigator$,                      //[Required] Class to create navigator instance
 +
                    $ChanceToShow: 2,                              //[Required] 0 Never, 1 Mouse Over, 2 Always
 +
                    $ActionMode: 1,                                //[Optional] 0 None, 1 act by click, 2 act by mouse hover, 3 both, default value is 1
 +
                    $AutoCenter: 0,                                //[Optional] Auto center navigator in parent container, 0 None, 1 Horizontal, 2 Vertical, 3 Both, default value is 0
 +
                    $Steps: 1,                                      //[Optional] Steps to go for each navigation request, default value is 1
 +
                    $Lanes: 1,                                      //[Optional] Specify lanes to arrange items, default value is 1
 +
                    $SpacingX: 0,                                  //[Optional] Horizontal space between each item in pixel, default value is 0
 +
                    $SpacingY: 0,                                  //[Optional] Vertical space between each item in pixel, default value is 0
 +
                    $Orientation: 1                                //[Optional] The orientation of the navigator, 1 horizontal, 2 vertical, default value is 1
 +
                },
 +
                $CaptionSliderOptions: {                            //[Optional] Options which specifies how to animate caption
 +
                    $Class: $JssorCaptionSlider$,                  //[Required] Class to create instance to animate caption
 +
                    $CaptionTransitions: _CaptionTransitions,      //[Required] An array of caption transitions to play caption, see caption transition section at jssor slideshow transition builder
 +
                    $PlayInMode: 1,                                //[Optional] 0 None (no play), 1 Chain (goes after main slide), 3 Chain Flatten (goes after main slide and flatten all caption animations), default value is 1
 +
                    $PlayOutMode: 3                                //[Optional] 0 None (no play), 1 Chain (goes before main slide), 3 Chain Flatten (goes before main slide and flatten all caption animations), default value is 1
 +
                }
 +
 +
            };
 +
            var jssor_slider1 = new $JssorSlider$("slider1_container", options);
 +
        });
 +
</script>
 +
    <div id="slider1_container" style="position: relative; top: 0px; left: 0px; width: 1080px;
 +
        height: 600px;">
 +
 +
        <!-- Loading Screen -->
 +
        <div u="loading" style="position: absolute; top: 0px; left: 0px;">
 +
            <div style="filter: alpha(opacity=70); opacity:0.7; position: absolute; display: block;
 +
                background-color: #000000; top: 0px; left: 0px;width: 100%;height:100%;">
 +
            </div>
 +
            <div style="position: absolute; display: block; background: url(../img/loading.gif) no-repeat center center;
 +
                top: 0px; left: 0px;width: 100%;height:100%;">
 +
            </div>
 +
        </div>
 +
 +
        <!-- Slides Container -->
 +
        <div u="slides" style="cursor: move; position: absolute; left: 0px; top: 0px; width: 1080px; height: 600px;
 +
            overflow: hidden;">
 +
            <div><div u="image" style = "lightgrey;text-align:center"><image style = "width:1080px" src="https://static.igem.org/mediawiki/2015/5/5e/GroupPic.jpeg"/></div>
 +
                <div u="caption" t="T" style="box-shadow: 0 0 10px 0;background-color:purple;padding:10px;position: absolute; top: 30px; left: 120px;border-style:solid;border-color:gold;border-width:10px">
 +
                    <p style = "color:white;font-size:30px;">
 +
                    <b>GRAND PRIZE WINNER
 +
                    </p>
 +
                    <p style = "color:white;font-size:30px;">
 +
                    BEST WIKI</b>
 +
                    </p>
 +
                    <p style = "color:white;font-size: 20px; margin:0">
 +
                    Nominated: Best Education and Public Engagement, Poster, Presentation, New Composite Part
 +
                    </p>
 +
                </div>
 +
                </div>
 +
            <div><img u="image" src="https://static.igem.org/mediawiki/2015/0/00/Tas_frontpage_1.png"/></div>
 +
            <div><div u="image" style = "lightgrey;text-align:center"><image src="https://static.igem.org/mediawiki/2015/d/df/Bg_fig6.gif"/></div>
 +
                <div u="caption" t="L" style="box-shadow: 0 0 10px 0;background-color:orange;padding:20px;position: absolute; top: 30px; left: 30px;">
 +
                    <p style = "color:white;font-size:32px;">
 +
                    INHIBITING GRANZYME B
 +
                    </p>
 +
                    <p style = "color:white;font-size: 20px">
 +
                    Our device produces a GzmB inhibitor
 +
                    </p>
 +
                </div>
 +
                </div>
 +
            <div><div u="image" style = "text-align:center"><image src="https://static.igem.org/mediawiki/2015/2/20/Exp_prototype.gif"/></div>
 +
                <div u="caption" t="B" style="box-shadow: 0 0 10px 0;background-color:orange;padding:20px;position: absolute; top: 480px; left: 214px;">
 +
                    <p style = "color:white;font-size:32px;">
 +
                    PROTOTYPE
 +
                    </p>
 +
                    <p style = "color:white;font-size: 20px">
 +
                    We designed and built a bandage with a semi-permeable membrane
 +
                    </p>
 +
                </div>
 +
            </div>
 +
            <div><div u="image" style = "text-align:center"><image src="https://static.igem.org/mediawiki/2015/6/6c/Tas_frontpage_2.jpeg"/></div>
 +
            <div u="caption" t="L" style="box-shadow: 0 0 10px 0;background-color:orange;padding:10px;position: absolute; top: 330px; left: 20px;">
 +
                    <p style = "width:350px; color:white;font-size:22px;">
 +
                    "I appreciate the interdisciplinary aspect of iGEM. Aside from its strong focus on science which I enjoyed, iGEM also incorporates human, design, and technological elements."
 +
                    </p>
 +
                    <p style = "color:white;font-size: 16px">
 +
                    - Joseph Chuang
 +
                    </p>
 +
                </div>
 +
            </div>
 +
        </div>
 +
       
 +
       
 +
        <!--#region Bullet Navigator Skin Begin -->
 +
        <!-- Help: http://www.jssor.com/development/slider-with-bullet-navigator-jquery.html -->
 +
        <style>
 +
            /* jssor slider bullet navigator skin 12 css */
 +
            /*
 +
            .jssorb12 div          (normal)
 +
            .jssorb12 div:hover    (normal mouseover)
 +
            .jssorb12 .av          (active)
 +
            .jssorb12 .av:hover    (active mouseover)
 +
            .jssorb12 .dn          (mousedown)
 +
            */
 +
            .jssorb12 {
 +
                position: absolute;
 +
            }
 +
            .jssorb12 div, .jssorb12 div:hover, .jssorb12 .av {
 +
                position: absolute;
 +
                /* size of bullet elment */
 +
                width: 16px;
 +
                height: 16px;
 +
                background: url(https://static.igem.org/mediawiki/2015/9/90/B12.png) no-repeat;
 +
                overflow: hidden;
 +
                cursor: pointer;
 +
            }
 +
            .jssorb12 div { background-position: -7px -7px; }
 +
            .jssorb12 div:hover, .jssorb12 .av:hover { background-position: -37px -7px; }
 +
            .jssorb12 .av { background-position: -67px -7px; }
 +
            .jssorb12 .dn, .jssorb12 .dn:hover { background-position: -97px -7px; }
 +
        </style>
 +
        <!-- bullet navigator container -->
 +
        <div u="navigator" class="jssorb12" style="bottom: 16px; right: 6px;">
 +
            <!-- bullet navigator item prototype -->
 +
            <div u="prototype"></div>
 +
        </div>
 +
        <!--#endregion Bullet Navigator Skin End -->
 +
        <a style="display: none" href="http://www.jssor.com">Image Slider</a>
 +
    </div>
 +
<br>
 +
<br>
 +
 +
<div class = "card" id = "bodycontainer" style = "overflow:hidden;font-family:Lato; text-align:left;">
 +
<div class = "col-sm-12">
 +
<h1 style = "padding:10px;background-color: rgb(33,150,243);color:white">
 +
ABSTRACT
 +
</h1>
 +
<div style = "font-size:20px; line-height:40px">
 +
            <div class = "col-sm-1"></div>
 +
            <div class = "col-sm-10"><br>
 +
<b>Elevated Granzyme B (GzmB)</b> levels are associated with many chronic inflammatory conditions including vascular, autoimmune and skin diseases. As a serine protease that induces apoptosis in tumor cells, GzmB is an essential part of the immune system. However, high levels of GzmB also result in the <b>random cleavage of extracellular matrix (ECM) proteins</b>, which leads to <b>damaged tissue structure and elasticity</b>. Our project aim is to <b>prevent tissue damage from chronic inflammation</b> by <b>limiting GzmB activity in the ECM</b> without affecting its intracellular functions. We mutated an extracellular protein (ACT) to allow it to bind and inhibit GzmB specifically in the ECM. To deliver this GzmB inhibitor into inflamed sites without bacteria entering the body, we envision two different prototypes: a bandage with a semi-permeable membrane to target localized sites, and a cream containing only the desired protein for general topical use.
 +
</div>
 +
            <br>
 +
<div class = "col-sm-12">
 +
<img class = "col-sm-12" src = "https://static.igem.org/mediawiki/2015/1/15/Tas_home_1.png">
 +
</div>
 +
</div>
 +
</div>
 +
 +
</div>
 +
</div>
 +
 +
<br>
 +
<br><br>
 +
 +
<canvas id="canvas-container" style = "z-index:-1"></canvas>
 +
<script type="text/javascript" src='https://2015.igem.org/Template:TAS_Taipei/js/field?action=raw&amp;ctype=text/javascript'></script>
 +
</body>
 +
 +
<!--?action=raw&amp;ctype=text/javascript-->
 +
 +
 +
</p>
 +
<!--
 +
NewPP limit report
 +
CPU time usage: 0.004 seconds
 +
Real time usage: 0.004 seconds
 +
Preprocessor visited node count: 4/1000000
 +
Preprocessor generated node count: 24/1000000
 +
Post‐expand include size: 0/2097152 bytes
 +
Template argument size: 0/2097152 bytes
 +
Highest expansion depth: 2/40
 +
Expensive parser function count: 0/100
 +
-->
 +
 +
<!-- Saved in parser cache with key 2015_igem_org:pcache:idhash:1828-0!*!*!*!*!*!* and timestamp 20170620134330 and revision id 412354
 +
-->
 +
</div> <div class="visualClear"></div>
 +
    </div>
 +
</div>
 +
    </div>
 +
</body>
 +
</html>
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 
{{ColumbiaNYC}}
 
{{ColumbiaNYC}}
 
<html>
 
<html>

Revision as of 17:10, 20 June 2017

<!DOCTYPE html> Team:TAS Taipei - 2015.igem.org

Loading menubar.....

Team:TAS Taipei

TAS Taipei iGEM Wiki




RANZYME B

GRAND PRIZE WINNER

BEST WIKI

Nominated: Best Education and Public Engagement, Poster, Presentation, New Composite Part

INHIBITING GRANZYME B

Our device produces a GzmB inhibitor

PROTOTYPE

We designed and built a bandage with a semi-permeable membrane

"I appreciate the interdisciplinary aspect of iGEM. Aside from its strong focus on science which I enjoyed, iGEM also incorporates human, design, and technological elements."

- Joseph Chuang

Image Slider


ABSTRACT


Elevated Granzyme B (GzmB) levels are associated with many chronic inflammatory conditions including vascular, autoimmune and skin diseases. As a serine protease that induces apoptosis in tumor cells, GzmB is an essential part of the immune system. However, high levels of GzmB also result in the random cleavage of extracellular matrix (ECM) proteins, which leads to damaged tissue structure and elasticity. Our project aim is to prevent tissue damage from chronic inflammation by limiting GzmB activity in the ECM without affecting its intracellular functions. We mutated an extracellular protein (ACT) to allow it to bind and inhibit GzmB specifically in the ECM. To deliver this GzmB inhibitor into inflamed sites without bacteria entering the body, we envision two different prototypes: a bandage with a semi-permeable membrane to target localized sites, and a cream containing only the desired protein for general topical use.















HOME
TEAM
PROJECT
Description
Design
Experiments
Notebook
InterLab
Contribution
Model
Results
Demonstrate
Improve
Attributions
PARTS
Parts
Basic Parts
Composite Parts
Part Collection
SAFETY
HUMAN PRACTICES
Silver HP
Integrated and Gold
Public Engagement
AWARDS
Applied Design
Entrepreneurship
Hardware
Measurement
Model
Plant
Software
JUDGING FORM

ColumbiaNYC

Team Abstract (Project Description)


Before you start:

Please read the following pages:

Styling your wiki

You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.

While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.

Wiki template information

We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Editing your wiki

On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!

Use WikiTools - Edit in the black menu bar to edit this page

Tips

This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:

  • State your accomplishments! Tell people what you have achieved from the start.
  • Be clear about what you are doing and how you plan to do this.
  • You have a global audience! Consider the different backgrounds that your users come from.
  • Make sure information is easy to find; nothing should be more than 3 clicks away.
  • Avoid using very small fonts and low contrast colors; information should be easy to read.
  • Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2017 calendar
  • Have lots of fun!
Inspiration

You can also view other team wikis for inspiration! Here are some examples:

Uploading pictures and files

You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to
T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)

UPLOAD FILES