Difference between revisions of "Team:Georgia State"
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| − | Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through | + | Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through intraplantar and intrathecal injections. We are using the expression of mambalgin (the subject of last year's GSU team project) to assess our ability to produce, purify, and detect new recombinant fusion proteins with a glutathione-s-transferase tag. </p> |
<a href="https://2017.igem.org/Team:Georgia_State/Description" class="btn">more</a> | <a href="https://2017.igem.org/Team:Georgia_State/Description" class="btn">more</a> | ||
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Revision as of 00:14, 2 November 2017
Georgia State University
A Novel Synthesis of Factor C
A Story of Blood and Venom
We’re Doing It #TheStateWay
Located at the heart of Downtown Atlanta, Georgia, GSU is among the top 20 most innovative institutions in the USA.
Mambalgin
Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through intraplantar and intrathecal injections. We are using the expression of mambalgin (the subject of last year's GSU team project) to assess our ability to produce, purify, and detect new recombinant fusion proteins with a glutathione-s-transferase tag.
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Horseshoe Crab Factor C
We will synthetically produce the factor C protein from the horseshoe crab blood and create a system to detect gram negative bacteria without the harvesting of horseshoe crabs.
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Kell Hall Rm# 439, 24 Peachtree Center Ave SE, Atlanta, Georgia 30303
