Difference between revisions of "Team:Georgia State"

 
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             <a class="dropdown-toggle" data-toggle="dropdown">Project
 
             <a class="dropdown-toggle" data-toggle="dropdown">Project
 
                 <ul class="dropdown-menu">
 
                 <ul class="dropdown-menu">
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                                 <li><a href="https://2017.igem.org/Team:Georgia_State/Description">Description</a></li>
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                                <li><a href="https://2017.igem.org/Team:Georgia_State/Design">Design</a></li>
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                                 <li><a href=" https://2017.igem.org/Team:Georgia_State/Description">Description</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:Georgia_State/Results">Results</a></li>                                         
 
                                 <li><a href="https://2017.igem.org/Team:Georgia_State/Results">Results</a></li>                                         
 
                                 <li><a href="https://2017.igem.org/Team:Georgia_State/Collaborations">Collaborations</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:Georgia_State/Collaborations">Collaborations</a></li>
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             <option value="/Team:Georgia_State/Team">Team</option>
 
             <option value="/Team:Georgia_State/Team">Team</option>
 
             <option value="/Team:Georgia_State/Attributions">Attributions</option>
 
             <option value="/Team:Georgia_State/Attributions">Attributions</option>
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            <option value="/Team:Georgia_State/Description">Description</option>
 
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            <option value="/Team:Georgia_State/Design">Design</option>
 
 
             <option value="/Team:Georgia_State/Results">Results</option>
 
             <option value="/Team:Georgia_State/Results">Results</option>
 
             <option value="/Team:Georgia_State/Collaborations">Collaborations</option>
 
             <option value="/Team:Georgia_State/Collaborations">Collaborations</option>
 
             <option value="/Team:Georgia_State/Parts">Parts</option>
 
             <option value="/Team:Georgia_State/Parts">Parts</option>
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            <option value="/Team:Georgia_State/Description">Description</option>
 
             <option value="/Team:Georgia_State/Design">Design</option>
 
             <option value="/Team:Georgia_State/Design">Design</option>
 
             <option value="/Team:Georgia_State/Contribution">Contribution</option>
 
             <option value="/Team:Georgia_State/Contribution">Contribution</option>
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             <option value="/Team:Georgia_State/Improvement">Improvement</option>
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             <option value="/Team:Georgia_State/Improvement">Improve</option>
 
             <option value="/Team:Georgia_State/Safety">Safety</option>
 
             <option value="/Team:Georgia_State/Safety">Safety</option>
 
             <option value="/Team:Georgia_State/Notebook">Notebook</option>
 
             <option value="/Team:Georgia_State/Notebook">Notebook</option>
 
             <option value="/Team:Georgia_State/Experiments">Experiments</option>
 
             <option value="/Team:Georgia_State/Experiments">Experiments</option>
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            <option value="/Team:Georgia_State/Engagement">Public Engagement</option>
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            <option value="/Team:Georgia_State/HP/Silver">Silver</option>
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            <option value="/Team:Georgia_State/HP/Gold_Integrated">Gold and Integrated</option>
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            <option value="/Team:Georgia_State/HP/ASL">ASL Gallery</option>
 
             <option value="https://igem.org/2017_Judging_Form?team=Georgia_State">Judging</option>
 
             <option value="https://igem.org/2017_Judging_Form?team=Georgia_State">Judging</option>
 
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                                 <p class="spacing-t">
 
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Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through intraplanter and intrathecal injections. </p>
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Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through intraplantar and intrathecal injections. We are using the expression of mambalgin (the subject of last year's GSU team project) to assess our ability to produce, purify, and detect new recombinant fusion proteins with a glutathione-s-transferase tag.  </p>
 
                                 <a href="https://2017.igem.org/Team:Georgia_State/Description" class="btn">more</a>
 
                                 <a href="https://2017.igem.org/Team:Georgia_State/Description" class="btn">more</a>
 
                               </div>
 
                               </div>
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                                 <h1 class="media-heading">Horseshoe Crab Factor C</h1>
 
                                 <h1 class="media-heading">Horseshoe Crab Factor C</h1>
 
                                 <div class="ruler-bottom"></div>
 
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                                 <p class="spacing-t">We will synthetically produce the factor C protein from the horseshoe crab blood and create a system to detect gram negative  
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                                 <p class="spacing-t">Horseshoe crab blood is used in a test to detect bacterial contamination in medical solutions and devices. We propose to replace this test with a synthetic protein consisting of human chorionic gonadotropin fused to factor C, the protein that activates the coagulation response in horseshoe crab blood.  Using this fusion protein and a simple pregnancy test strip we hope to create a system to detect gram negative  
 
                                 bacteria without the harvesting of horseshoe crabs.
 
                                 bacteria without the harvesting of horseshoe crabs.
 
                                 </p>
 
                                 </p>

Latest revision as of 02:39, 2 November 2017

A Novel Synthesis of Factor C

A Story of Blood and Venom

We’re Doing It #TheStateWay


Located at the heart of Downtown Atlanta, Georgia, GSU is among the top 20 most innovative institutions in the USA.

Mambalgin

Mambalgin is a potent analgesic protein found in the venom of the Black Mamba snake (Dendroaspis polylepis). This protein has been found to inhibit acid-sensing ion channels (ASICs) in the central and peripheral nervous systems of mice through intraplantar and intrathecal injections. We are using the expression of mambalgin (the subject of last year's GSU team project) to assess our ability to produce, purify, and detect new recombinant fusion proteins with a glutathione-s-transferase tag.

more

Horseshoe Crab Factor C

Horseshoe crab blood is used in a test to detect bacterial contamination in medical solutions and devices. We propose to replace this test with a synthetic protein consisting of human chorionic gonadotropin fused to factor C, the protein that activates the coagulation response in horseshoe crab blood. Using this fusion protein and a simple pregnancy test strip we hope to create a system to detect gram negative bacteria without the harvesting of horseshoe crabs.

more

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