Difference between revisions of "Team:GZHS-United"

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{{GZHS-United}}
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<!DOCTYPE HTML>
 
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<title>Home</title>
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<link rel="stylesheet" type="text/css" href="css/style4.css" />
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<script src="js/wow.min.js"></script>
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new WOW().init();
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<style>
  
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.dropdown_menu {
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background:#000; filter:alpha(opacity:30); opacity:0.5;
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.dropdown_title {
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margin:0 10px;
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<h1>Project description</h1>
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<p>Bacillus thuringiensis israelensis (Bti) and Bacillus sphaericus(BS)are naturally existed bacterial that could be extracted from dirt, insect body, unclean water et al. Both of them are applied widely as biological larvicides over urban areas as they target specific insects and do not contaminate the environment. Cry protein family usually form during Bti spore-forming process. Cry4Ba is one of the studied crystal toxin protein that could combine with mosquito larvae midgut epithelia causing midgut to decay thus Aedes mosquito death. Mosquitocidal toxin 1 (Mtx1) protein form at BS trophophase stage. After eaten by mosquito larvae, Mtx protein would decomposed into peptided which leads to morphological change in mosquito larvae cells.  </p>
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<p>A variety of mixed toxic proteins could delay the emergence and development of insecticide resistance. BS is easy to make the target pests develop resistance, mainly due to single factor genetic resistance. Such resistance cases was already reported in France, India, Brazil, China and other countries around the world.  Traditional insecticide resistance management strategies include rotation and blending of Bti with Bs, and new strategies include synthetic biology aim to expand toxin diversity against mosquito larvae to avoid the emergence of larvecide resistance. </p>
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<p>We believe that our research could ease the mosquito born disease burden  through genetically mix different mosquito toxin protein which not only add to the field of synthetic biology, but also help with larvecide resistance management through the implementation of scientific rigor to the process of creating new type to larvecide for insecticide industry. Our goal is to create a genetic modified mosquito larvae toxin and test for adaptation to mosquito breading sites in local environments.  The timeline above outlines major work done to achieve our goals. </p>
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</div>  
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}
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</script>
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</head>
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<body>
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<div class="header-banner" id="head">
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<div class="slider">
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<div class="callbacks_container">
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<ul class="rslides" id="slider">
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<li>
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<img src="images/T--GZHS-United--home_Home-1.jpg" alt="">
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<div class="caption wow bounceIn animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="logo">
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<a href="https://2017.igem.org/Team:GZHS-United">mos quit X cry</a>
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</div>
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<h3>GZHS-United</h3>
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</div>
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</li>
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<li>
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<img src="images/T--GZHS-United--home_Home-2.jpg" alt="">
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<div class="caption wow bounceIn animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="logo">
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<a href="https://2017.igem.org/Team:GZHS-United">mos quit X cry</a>
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</div>
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<h3>GZHS-United</h3>
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</div>
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</li>
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<li>
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<img src="images/T--GZHS-United--home_Home-3.jpg" alt="">
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<div class="caption wow bounceIn animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="logo">
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<a href="https://2017.igem.org/Team:GZHS-United">mos quit X cry</a>
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</div>
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<h3>GZHS-United</h3>
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</div>
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</li>
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<li>
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<img src="images/T--GZHS-United--home_Home-4.jpg" alt="">
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<div class="caption wow bounceInLeft animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="logo">
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<a href="https://2017.igem.org/Team:GZHS-United">mos quit X cry</a>
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</div>
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<h3>GZHS-United</h3>
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</div>
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</li>
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</ul>
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</div>
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</div>
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<div class="header-bottom">
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<div class="fixed-header">
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<div class="container">
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<div class="top-menu">
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<span class="menu"><img src="images/T--GZHS-United--home_nav.png" alt=""/> </span>
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<ul>
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<nav class="cl-effect-5">
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<li><a href="https://2017.igem.org/Team:GZHS-United"><span data-hover="HOME">HOME</span></a></li>
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<li class="dropdown">
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<a class="dropdown-toggle" id="dropdownMenu1" data-toggle="dropdown" href="#">
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<span data-hover="TEAM">TEAM</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu1">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Team">Team</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Attributions">Attributions</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Collaborations">Collaborations</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a class="dropdown-toggle" id="dropdownMenu2" data-toggle="dropdown" href="#">
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<span data-hover="PROJECT">PROJECT</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu2">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Description">Description</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Design">Design</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Experiments">Experiments</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a class="dropdown-toggle" id="dropdownMenu3" data-toggle="dropdown" href="#">
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<span data-hover="RESULTS">RESULTS</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu3">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Results">Results</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Model">Modeling</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Demonstrate">Demonstrate</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="#">Improve</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="#">Contribution</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a class="dropdown-toggle" id="dropdownMenu4" data-toggle="dropdown" href="#">
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<span data-hover="PARTS">PARTS</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu4">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Parts">Parts</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a  class="dropdown-toggle" id="dropdownMenu5" data-toggle="dropdown" href="#">
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<span data-hover="NOTEBOOK">NOTEBOOK</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu5">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Gallery">Gallery</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Timeline">Timeline</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/InterLab">InterLab</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a class="dropdown-toggle" id="dropdownMenu6" data-toggle="dropdown" href="#">
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<span data-hover="SAFETY">SAFETY</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu6">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Safety">Safety</a>
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</li>
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</ul>
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</li>
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<li class="dropdown">
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<a  class="dropdown-toggle" id="dropdownMenu7" data-toggle="dropdown" href="#">
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<span data-hover="HUMAN_PRACTICE" class="dropdown_title">HUMAN PRACTICE</span>
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</a>
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<ul class="dropdown-menu dropdown_menu" role="menu" aria-labelledby="dropdownMenu7">
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/HP/Silver">Silver</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/HP/Gold_Integrated">Gold & Integrated</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Engagement">Public Engagement</a>
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</li>
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<li role="presentation">
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<a role="menuitem" tabindex="-1" href="https://2017.igem.org/Team:GZHS-United/Entrepreneurship">Entrepreneurship</a>
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</li>
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</ul>
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</li>
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</nav>
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</ul>
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<!-- script for menu -->
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<!--script-nav-->
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<script>
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$("span.menu").click(function(){
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$(".top-menu ul").slideToggle("slow" , function(){
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});
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});
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</script>
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<div class="clear"></div>
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<!-- script-for sticky-nav -->
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<script>
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$(document).ready(function() {
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var navoffeset=$(".header-bottom").offset().top;
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$(window).scroll(function(){
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var scrollpos=$(window).scrollTop();
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if(scrollpos >=navoffeset){
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$(".header-bottom").addClass("fixed");
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}else{
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$(".header-bottom").removeClass("fixed");
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}
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});
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</script>
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</div>
  
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<h5>Before you start: </h5>
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</div>
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<p> Please read the following pages:</p>
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</div>
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<ul>
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<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
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<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
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<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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</ul>
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</div>
 
</div>
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<div class="content">
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<div class="column half_size" >
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<div class="about-section" id="about">
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<div class="highlight">
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<div class="container">
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<h5> Styling your wiki </h5>
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<h3>about us </h3>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<div class="main wow bounceInRight animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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<div class="view view-fourth ">
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<a href="https://2017.igem.org/Team:GZHS-United/Team">
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<img src="images/T--GZHS-United--home_Home-6.jpg" />
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<div class="mask">
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<h2>Students</h2>
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<p>OUR STUDENTS</p>
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</div>
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</a>
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</div>
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<div class="view view-fourth view1">
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<a href="https://2017.igem.org/Team:GZHS-United/Team">
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<img src="images/T--GZHS-United--home_Home-7.jpg" />
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<div class="mask">
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<h2>Introducers</h2>
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<p>OUR INTRODUCERS</p>
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</div>
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</a>
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</div>
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<div class="view view-fourth">
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<a href="https://2017.igem.org/Team:GZHS-United/Team">
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<img src="images/T--GZHS-United--home_Home-8.jpg" />
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<div class="mask">
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<h2>Advicors</h2>
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<p>OUR ADVICORS</p>
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</div>
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</a>
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</div>
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<div class="clearfix"></div>
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</div>
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</div>
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</div>
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<div class="menu-section">
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<div class="container">
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<h3> PROJECT ABSTRACT</h3>
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<div class="menu-grids wow bounceIn animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="col-md-4 menu-grid">
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<a href="https://2017.igem.org/Team:GZHS-United/Description">
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<img src="images/T--GZHS-United--home_mtx1.png" class="img-responsive" alt="" />
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<div class="menu-info">
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<h5>MTX1</h5>
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</div>
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</a>
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</div>
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<div class="col-md-4 menu-grid ">
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<img src="images/T--GZHS-United--home_gif.gif" class="img-responsive" alt="" />
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</div>
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<div class="col-md-4 menu-grid menu1 ">
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<a href="https://2017.igem.org/Team:GZHS-United/Description">
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<img src="images/T--GZHS-United--home_cry4ba.png" class="img-responsive" alt="" />
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<div class="menu-info">
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<h5>Cry4Ba</h5>
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</div>
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</a>
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</div>
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<div class="clearfix"></div>
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</div>
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</div>
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</div>
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<div class="our_work">
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<div class="container">
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<h3>OUR WORK</h3>
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<div class="wow bounceInLeft animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<p>Bs mainly target culex mosquitoes, while Bti exibits strong killing effect against Aedes mosquitoes. However, if they work together in one system, the efficiency of both the two protein can improve significantly. Because of that, we decided to build up a system which consist of these two proteins based on synthetic biology. So as to ensure that we can get purified protein, we used E.coli as our bio-chasis to synthesize these proteins and applied them in toxicity test. For there had been many bio-bricks from Cry family in iGEM, the new part Mtx1 we introduced into the biobricks in our project may be applied to strengthen the efficiency of former parts of Cry.</p>
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</div>
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</div>
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</div>
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<div class="contact-section">
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<div class="container">
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<h3>contact us</h3>
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<div class="contact-grids wow bounceInRight animated" data-wow-delay="0.4s" style="visibility: visible; -webkit-animation-delay: 0.4s;">
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<div class="col-md-4 contactgrid">
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<input type="text" class="text" value=" name" onFocus="this.value = '';" onBlur="if (this.value == '') {this.value = ' name';}">
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</div>
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<div class="col-md-4 contactgrid">
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<input type="text" class="text" value="email" onFocus="this.value = '';" onBlur="if (this.value == '') {this.value = 'email';}">
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</div>
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<div class="col-md-4 contactgrid">
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<input type="text" class="text" value="phone" onFocus="this.value = '';" onBlur="if (this.value == '') {this.value = 'phone';}">
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</div>
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<div class="col-md-8 contactgrid1">
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<textarea onFocus="if(this.value == 'Your Message') this.value='';" onBlur="if(this.value == '') this.value='Your Message';" >Your Message</textarea>
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</div>
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<div class="col-md-4 contactgrid2">
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<input type="button" value="send message">
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  </div>
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  <div class="clearfix"></div>
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</div>
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</div>
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<script type="text/javascript">
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$(document).ready(function() {
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$().UItoTop({ easingType: 'easeOutQuart' });
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<h5> Wiki template information </h5>
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});
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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</script>
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<a class="scroll" href="#head" id="toTop" style="display: block;"> <span id="toTopHover" style="opacity: 1;"> </span></a>
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<h5> Editing your wiki </h5>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2017.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
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<div class="column half_size" >
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<h5>Tips</h5>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<ul>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li>
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<li>Have lots of fun! </li>
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<h5>Inspiration</h5>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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<h5> Uploading pictures and files </h5>
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<p> You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br>
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<a href="https://2017.igem.org/Special:Upload">
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UPLOAD FILES
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Revision as of 14:46, 24 September 2017

<!DOCTYPE HTML> Home

PROJECT ABSTRACT

MTX1
Cry4Ba

OUR WORK

Bs mainly target culex mosquitoes, while Bti exibits strong killing effect against Aedes mosquitoes. However, if they work together in one system, the efficiency of both the two protein can improve significantly. Because of that, we decided to build up a system which consist of these two proteins based on synthetic biology. So as to ensure that we can get purified protein, we used E.coli as our bio-chasis to synthesize these proteins and applied them in toxicity test. For there had been many bio-bricks from Cry family in iGEM, the new part Mtx1 we introduced into the biobricks in our project may be applied to strengthen the efficiency of former parts of Cry.

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