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| <h5>Chitosan Hydrogel solidified in Alginate-Quercetin solution</h4> | | <h5>Chitosan Hydrogel solidified in Alginate-Quercetin solution</h4> |
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− | <h4>Multiple Choice Questions</h4>
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− | <p>The main mode for questioning are <b>Mulitple Choice Questions</b>. That means, you can expect multiple right answers from a user <b>or</b> ask multiple questions simultaneously.</p>
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| <h5>Chitosan-Agarose</h5> | | <h5>Chitosan-Agarose</h5> |
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| + | <h4>Multiple Choice Questions</h4> |
| + | <p>A hydrogel composed of chitosan and agarose fulfils most of the required criteria for an “ideal” wound dressing. |
| + | Agarose is a biocompatible, linear polysaccharide which is extracted from marine algae. It consists of 1,4-linked 3,6-anhydro-α-L-galactose and 1,3-linked β-D-galactose derivatives. |
| + | <br>When the agarose is dissolved in water, it forms a gel with a three-dimensional scaffold and a porous structure providing a good environment for cell adhesion, spreading and proliferation. It is capable of gelling within the desired site because of the polymer interaction. By varying the concentration of agarose in the hydrogel, the mechanical properties, which are similar to those of tissues, can easily be adjusted <a href="#[4]">[4]</a>. |
| + | <br>The preparation of such a hydrogel is quite simple. The desired amount of agarose is dissolved in water. 1 % acetic acid and the desired amount of chitosan are dissolved in water, simultaneously. Both solution are mixed and heated while stirring until the solution is clear. We transferred this mixture in a petri dish with the desired thickness. |
| + | We examined gels with concentrations of 1 -3 % agarose and 1 – 3 % chitosan. The most promising variation is the hydrogel with 1 % agarose and 1 % chitosan. It forms a stable, elastic gel which allows easy handling. |
| + | The simplicity of preparing the hydrogel and its multifunctionality allows many future applications of agarose-based hydrogels <a href="#[5]">[5]</p> |
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| <p>A hydrogel composed of chitosan and agarose fulfils most of the required criteria for an “ideal” wound dressing. | | <p>A hydrogel composed of chitosan and agarose fulfils most of the required criteria for an “ideal” wound dressing. |
| Agarose is a biocompatible, linear polysaccharide which is extracted from marine algae. It consists of 1,4-linked 3,6-anhydro-α-L-galactose and 1,3-linked β-D-galactose derivatives. | | Agarose is a biocompatible, linear polysaccharide which is extracted from marine algae. It consists of 1,4-linked 3,6-anhydro-α-L-galactose and 1,3-linked β-D-galactose derivatives. |