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+ | <h1 align=middle>Model</h1> | ||
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+ | <p>The files for the optimization of Block two are provided here.</p> | ||
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+ | <!-- https://2017.igem.org/File:Cost_function.m --> | ||
+ | <!-- https://2017.igem.org/File:Modell.m --> | ||
+ | <!-- https://2017.igem.org/File:PathwayIGEM.m --> | ||
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Revision as of 16:56, 1 November 2017
Modelling
Our modelling process considers three successional blocks: The first one describes the synthesis and excretion of the desired enzymes, this is followed by the hair and lipid degradation block and the last one depicts the synthesis of the rose scent. The modelling and simulation team aims to describe the whole system with an equational system which characterizes the intracellular and extracellular concentration time courses of all enzymes, the degradation time courses as well as the produced rose scent. In order to find the best enzyme composition for the maximal hair and lipid breakdown in a specific time period the 2nd modelling block is used to perform an optimization by the method of least square. Finally, we want to examine the system’s sensitivity to fluctuations in temperature and pH value.