Difference between revisions of "Team:TECHNION-ISRAEL/Demonstrate"
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Revision as of 15:41, 1 November 2017
Tolerance Assay
In an attempt to show proof of concept we set out to test our system under realistic conditions. Ideally we would have tested our constructs in-vivo for tolerance
induction
[1]
.
This, unfortunately, was not possible within the framework of iGEM, as animal experimentation is generally discouraged, and the time frame did not allow for an animal experimentation ethics permit.
In light of these considerations, our team has worked very hard to develop an effective and novel in-vitro assay for tolerance induction.
- Baranyi, Ulrike, et al. "Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells." The Journal of Immunology 180.12 (2008): 8168-8175.
Department of Biotechnology & Food Engineering
Technion – Israel Institute of Technology
Haifa 32000, Israel
igem.technion.2017@gmail.com
