Team:NIPER-Guwahati/part
Basic Parts
Deoxyribozymes are DNA molecules with catalytic activity.The current part is an evolved deoxyribozyme (DNAzyme) with the ability to cleave oncogene Bcl-2 mRNA. This DNAzyme has been evolved after 10 rounds of In Vitro selection. The selection was directly been carried out with 60 ntds Bcl-2 mRNA template for evolving RNA cleaving DNAzyme. The DNAzyme evolved with our unique strategy are trans Deoxyribozymes.
| Name | Description | Length |
|---|---|---|
| 10V13 | This part is an evolved DNAzyme which can cleave Bcl-2-mRNA | 70 ntds |
| 10V21 | This part is an evolved DNAzyme which can cleave Bcl-2-mRNA | 70 ntds |
| 10V24 | This part is an evolved DNAzyme which can cleave Bcl-2-mRNA | 70 ntds |
| 10V34 | This part is an evolved DNAzyme which can cleave Bcl-2-mRNA | 70 ntds |
| 10V35 | This part is an evolved DNAzyme which can cleave Bcl-2-mRNA | 70 ntds |
