Why Model?

Scientific models are mathematical renditions of real-world systems. In synthetic biology, models are often used to define the kinetics of biochemical systems to aid in the visualization of information, and can be used to predict the behavior or outcome of biological systems.

Our Model

The goal of our model is to simulate the expected behavior of our transformed Lactobacillus plantarum after consumption. We focused on modeling the binding reaction of glutamate decarboxylate and L-glutamate, dependent on the cofactor pyridoxal- 5"phosphate (PLP). Plp binds to the C-terminal domain of the gadB. We looked specifically at how our Lactobacillus plantarum would encode the gadB gene and encode glutamate decarboxylate.