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Revision as of 11:46, 23 June 2017
Project Description
Eutrophication is having a globally devastating effect on biodiversity. Our team is working on a GMO that can be used to remove phosphate from polluted waterways. We will build on the natural phosphorous storage pathway in E. coli by packaging an enhanced polyphosphate kinase into a pdu bacterial microcompartment (BMC). The BMC will protect the polyphosphate product from degradation by intracellular enzymes. We hope to provide a platform that can be exported into a more environmentally robust organism for use in phosphorous recycling. We will package an enhanced polyphosphate kinase (PPK) in a bacterial microcompartment, protecting the reaction product from degradation.