Difference between revisions of "Team:Manchester/Achievement"

This is a list of iGEM's requirements for the bronze, silver and gold medals. We have made it clear which of these criteria we have met in our project. Click to see the requirements of each medals and what we have achieved.

COLLABORATIONS

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PARTS

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INTEGRATED HP

To explore the viability of Phosphostore in the real-world, we consulted experts in the water industry. Their insights into innovation management, in addition to our exploration on intellectual property, scale-up and legislation informed our business plan. They also inspired our international collaboration to generate a worldwide legislation map. Expert consultation also informed additional experiments on the thermal stability of PPK, to test possible applications in a domestic setting.

MODELLING

Continuous culture modelling allowed us to estimate the yearly cost of treating wastewater using Phosphostore leading us to perform a major re-design of our device. We used an ensemble modelling approach to predict the operating characteristics of our phosphate starvation operon as a regulatory system for controlling BMC synthesis. We also used Design of Experiments to identify the optimal conditions for PPK expression and optimum conditions for BMC expression.

ENTERPRISE

Our integrated business plan was shaped by interactions with experts in the water industry. We considered international markets for Phosphostore, beyond the local water industry, which helped us focus on Canadian wastewater treatment plants as a promising target. Our competitor analysis informed us on current phosphate removal technologies and potential roadblocks. Our company plan was shaped by exploratory research on scaling-up, which guided our modelling to estimate production costs and economic feasibility.

MEASUREMENT

Our business plan is highly integrated and shaped by interactions with stakeholders in the water industry. We considered various international markets for Phosphostore, beyond our focus on the local Manchester water industry, which helped us focus on Canadian wastewater treatment plants as our most promising target customers. Our competitor analysis was also shaped by our interaction with experts, informing us on current phosphate removal technologies and potential roadblocks. Our Phosphostore company and product description were shaped by exploratory research on scale-up considerations, which guided our computational modelling to estimate the production cost and economic feasibility of our system.

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-<div style="text-align: center; padding: 10px"> <h4>INTEGRATED HUMAN PRACTICES</h4>
+<div style="text-align: center; padding: 10px"> <h4>INTEGRATED HP</h4>
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-To explore the viability of Phosphostore in a real-world setting, we consulted major stakeholders in the water industry. The detailed insights into the practices of innovation management in the water industry, in addition to our exploration on intellectual property, scale-up and legislation informed our extensive business plan. They also inspired our international collaboration with other iGEM teams to generate a worldwide legislation map. Consultation with stakeholders has also led us to perform additional experiments on the thermal stability of our PPK, to show the feasibility of applying Phosphostore devices in a domestic setting.
+To explore the viability of Phosphostore in the real-world, we consulted experts in the water industry. Their insights into innovation management, in addition to our exploration on intellectual property, scale-up and legislation informed our business plan. They also inspired our international collaboration to generate a worldwide legislation map. Expert consultation also informed additional experiments on the thermal stability of PPK, to test possible applications in a domestic setting.
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 <div style="text-align: center; padding: 10px"> <h4>MODELLING</h4>
 <p>
-Computational modelling guided our project in three major areas:
+Continuous culture modelling allowed us to estimate the yearly cost of treating wastewater using Phosphostore leading us to perform a major re-design of our device. We used an ensemble modelling approach to predict the operating characteristics of our phosphate starvation operon as a regulatory system for controlling BMC synthesis. We also used Design of Experiments to identify the optimal conditions for PPK expression and optimum conditions for BMC expression.
-) Continuous culture modelling allowed us to estimate the yearly cost of treating wastewater using Phosphostore. As a result we performed a major re-design of the intended device.
-) We used an innovative ensemble modelling approach to predict the operating characteristics of our phosphate starvation operon as a regulatory system for controlling microcompartment synthesis.
-) We used statistical Design of Experiments (DoE) to optimize the expression of PPK. Two rounds of DoE enabled us to identify the optimal conditions for expression. DoE was also used to identify the optimum conditions for microcompartment expression.
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@@ Line 155: / Line 149: @@
 <div style="text-align: center; padding: 10px"> <h4>ENTERPRISE</h4>
 <p>
-Our business plan is highly integrated and shaped by interactions with stakeholders in the water industry. We considered various international markets for Phosphostore, beyond our focus on the local Manchester water industry, which helped us focus on Canadian wastewater treatment plants as our most promising target customers. Our competitor analysis was also shaped by our interaction with experts, informing us on current phosphate removal technologies and potential roadblocks. Our Phosphostore company and product description were shaped by exploratory research on scale-up considerations, which guided our computational modelling to estimate the production cost and economic feasibility of our system.
+Our integrated business plan was shaped by interactions with experts in the water industry. We considered international markets for Phosphostore, beyond the local water industry, which helped us focus on Canadian wastewater treatment plants as a promising target. Our competitor analysis informed us on current phosphate removal technologies and potential roadblocks. Our company plan was shaped by exploratory research on scaling-up, which guided our modelling to estimate production costs and economic feasibility.
 </p>
 </div>