Difference between revisions of "Team:Hong Kong HKU"

 
(139 intermediate revisions by 3 users not shown)
Line 1: Line 1:
−
{{Hong_Kong_HKU}}
+
{{:Team:Hong_Kong_HKU/Templates/NavBar}}
 
<html>
 
<html>
 +
<head>
 +
<link href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css" rel="stylesheet">
 +
<link href="https://fonts.googleapis.com/css?family=Roboto" rel="stylesheet">
 +
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js">
 +
</script>
 +
</head>
 +
<div id = "main-body">
 +
  <img src="https://static.igem.org/mediawiki/2017/8/86/16681805_1351181934924813_260556013027435769_n.png" alt="" width=100% style="height:80%">
 +
  <div>
 +
   
 +
    <div style="border-style: solid; border-color:green;padding: 25px;margin: 25px;" >
 +
      <h1> About this project </h1>
  
 +
      <p style="text-align:justify">Greetings!
  
−
<div class="column full_size" >
+
        By focusing on the intriguing world of diagnostic probes, our project aims to design an effective DNA nanostructure for Disease detection. Contrary to HKU iGEM Team 2016 design, we have come up with an alternative tetrahedron structure, in which the 3D tetrahedron is only formed upon binding to the target sequence. Our ultimate goal is to enable our functional DNA nanostructure to be synthesized and self-assembled inside E. coli. They will detect specific biomarkers expressed in the diseased cells. This website will guide you on our journey throughout the iGEM Competition 2017. Click to explore and enjoy! </p>
−
<img src="https://static.igem.org/mediawiki/2017/a/a6/T--Hong_Kong_HKU--bg.jpg" alt="background_image" height="300" width="2000">
+
      </div>
 +
<center>
 +
   
 +
   
 +
<br>
 +
      <div style="float: left; ">
 +
<center>
 +
        <a href="https://2017.igem.org/Team:Hong_Kong_HKU/Attributions" style="margin-left:30px"><img src="https://static.igem.org/mediawiki/2017/7/7a/TeamHKU.png" style="width:10%; height:90px; padding-right:20px" > </a>
 +
        <a href="https://2017.igem.org/Team:Hong_Kong_HKU/Collaborations"><img src="https://static.igem.org/mediawiki/2017/e/eb/CollaborationHKU.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/HP/Silver"><img src="https://static.igem.org/mediawiki/2017/4/4f/Human_practice.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/Notebook"><img src="https://static.igem.org/mediawiki/2017/d/d9/NotebookHKU.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/InterLab"><img src="https://static.igem.org/mediawiki/2017/6/63/InterlabHKU.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/Parts"><img src="https://static.igem.org/mediawiki/2017/6/62/PartsHKU.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/Results"><img src="https://static.igem.org/mediawiki/2017/c/c4/ResultsHKU.png" style="padding-right:20px; width:10%; height:90px"  > </a>
 +
<a href="https://2017.igem.org/Team:Hong_Kong_HKU/Description"><img src="https://static.igem.org/mediawiki/2017/c/c4/DescriptionHKU1.png" style="padding-right:20px; width:10%; height:90px" > </a>
 +
</center>
 +
      </div>
 +
     
 +
 
 +
 
 +
 
 +
 
 +
 
 +
<img src="https://2017.igem.org/File:BiosafetyHKU.png" alt="">
 +
<img src="" alt="">
 +
 
 +
<center>
 +
<br><br>
 +
<div id="myCarousel" class="carousel slide" data-ride="carousel" style="width:800px;">
 +
  <!-- Indicators -->
 +
  <ol class="carousel-indicators">
 +
    <li data-target="#myCarousel" data-slide-to="0" class="active"></li>
 +
    <li data-target="#myCarousel" data-slide-to="1"></li>
 +
    <li data-target="#myCarousel" data-slide-to="2"></li>
 +
    <li data-target="#myCarousel" data-slide-to="3"></li>
 +
    <li data-target="#myCarousel" data-slide-to="4"></li>
 +
    <li data-target="#myCarousel" data-slide-to="5"></li>
 +
 
 +
 
 +
 
 +
  </ol>
 +
 
 +
  <!-- Wrapper for slides -->
 +
  <div class="carousel-inner">
 +
    <div class="item active">
 +
      <img src="https://static.igem.org/mediawiki/2017/1/1f/Planing_HKU.jpeg" alt="HKU iGEM 2017 Team Spirit", width=400px, height=400px>
 +
      <div class="carousel-caption">
 +
        <h3> HKU iGEM 2017 Team Spirit</h3>
 +
        <p>Initial group discussions</p>
 +
      </div>
 +
    </div>
 +
 
 +
    <div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2017/1/1f/Learning_for_youngHKU.jpeg" alt="HKU iGEM 2017 Collaboration", width=400px, height=400px>
 +
      <div class="carousel-caption">
 +
        <h3>HKU iGEM 2017 Collaboration</h3>
 +
        <p>Learning from the youngsters</p>
 +
      </div>
 +
    </div>
 +
 
 +
    <div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2017/2/20/DesignHKU1.png" alt="Explaning Concepts", width=800px, style="margin-bottom:400px;">
 +
      <div class="carousel-caption">
 +
        <h3>HKU iGEM 2017 Design</h3>
 +
 
 +
    </div>
 
</div>
 
</div>
 +
<div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2017/6/6b/Interlab_Fluorescence_Graph.PNG" alt="" , width=800px, style="margin-bottom:200px;">
 +
      <div class="carousel-caption">
 +
        <h3>HKU iGEM 2017 Interlab</h3>
 +
        <p>To be better we work together </p>
  
−
+
 
−
<h2><b>Project Description</b></h2>
+
 
 +
      </div>
 +
    </div>
 +
 
 +
    <div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2017/8/84/Teachingsecondaryschool.jpg" alt="Explaning Concepts" , width=400px, height=400px>
 +
      <div class="carousel-caption">
 +
        <h3>HKU iGEM Human Practice</h3>
 +
        <p>Paying it forward </p>
 +
 
 +
      </div>
 +
    </div>
 +
 
 +
<div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2017/d/d5/HKUBio2.jpg" alt="", width=400px, height=400px>
 +
      <div class="carousel-caption">
 +
        <h3>HKU iGEM 2017 Biosafety Conference</h3>
 +
        <p>Better safe than sorry</p>
 +
      </div>
 +
    </div>
  
  
  
−
<div class="panel-group" id="BackgroundContent" role="tablist" aria-multiselectable="true">
 
−
<p class="text-justify" align="left"><font face="san-serif" size="3">
 
−
The field of DNA nanotechnology has proved to be one of the fastest growing fields in synthetic biology. Recent advances have focused on the development of DNA origami, tweezer structures and various other two and three dimensional structures, with the aim of applying such structures into areas such as diagnostics, drug delivery, detection and more.
 
−
</br></br>
 
−
<b>Hypothesis:</b>
 
−
</br>
 
−
Through our project, we expect to follow in the footsteps of such advancements, however taking them a step further to develop a three dimensional DNA nanostructure that can undergo an induced structural change in the presence of its specific nucleic acid targets (RNA or DNA) not solely in vitro but also in living cells after expression.
 
−
</br></br>
 
−
<b>Objectives:</b>
 
−
</br>
 
−
Our objectives would be to first prove the efficiency and accuracy of our structure in detecting its respective target in vitro with the application of various laboratory techniques, for example gel electrophoresis and colorimetric assays, followed by the expression of our DNA nanostructure in organisms, namely <i>E.coli</i>, after which the structure can be extracted and tested as well again.
 
−
</br>
 
−
In brief, we will aim to construct a three dimensional DNA nanostructure that can be used for the detection of nucleic acid markers and explore its functionality, both in vitro and in living cells.
 
−
</font></p>
 
−
       
 
 
   </div>
 
   </div>
 +
 +
 +
 +
 +
 +
<div class="clear"></div>
 +
</div>
 +
</center>
 +
<style>
 +
/* custom css */
 +
#para-1 {
 +
    padding-right: 20px;
 +
}
 +
/*-- Remove borders, float content left and remove padding/margin */
 +
        #globalWrapper, #content{
 +
margin-left: 10px;
 +
                width: 98%;
 +
                height: 98%;
 +
}
 +
/* Remove header footer and borders */
 +
#contentSub, #search-controls, .firstHeading, #footer-box, #catlinks, #p-logo {
 +
    display:none;}
 +
#top-section {
 +
    border: none;
 +
    height: 0px;}
 +
#content {
 +
    border: none;}
 +
#main-body {
 +
    margin-top: 120px;
 +
}
 +
#main-text {
 +
margin-top: 10px;
 +
}
 +
</style>
  
 
</html>
 
</html>

Latest revision as of 18:41, 1 November 2017

About this project

Greetings! By focusing on the intriguing world of diagnostic probes, our project aims to design an effective DNA nanostructure for Disease detection. Contrary to HKU iGEM Team 2016 design, we have come up with an alternative tetrahedron structure, in which the 3D tetrahedron is only formed upon binding to the target sequence. Our ultimate goal is to enable our functional DNA nanostructure to be synthesized and self-assembled inside E. coli. They will detect specific biomarkers expressed in the diseased cells. This website will guide you on our journey throughout the iGEM Competition 2017. Click to explore and enjoy!