Difference between revisions of "Team:TU Dresden"

 
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{{TU_Dresden/Header}}
 
{{TU_Dresden/Header}}
 
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    <div id="bannerquote" style="flush: right;">Entering A Whole New Universe Of Applications!</div>
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<h1 class="box-heading">EncaBcillus – It’s a trap!</h1>
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<p>Synthetic biology wants to go beyond the pure biological by integrating concepts from chemistry or physics into the living world. At this interphase, our project wants to introduce Peptidosomes as a new fundamental approach for generating and applying encapsulated bacteria.  
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These spheres possess advantageous properties like stability in different media and a mesh-like structure that allows for the selective exchange of compounds via diffusion. Therefore, we are able to benefit from the entrapped cells’ abilities, while ensuring that they are not released into their surroundings.
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Using the powerful genetics of <i>Bacillus subtilis</i> and its secretory capabilities we demonstrate communication and cooperation between separately encapsulated bacterial populations as well as the environment. Peptidosomes can be further enhanced by incorporating magnetic or biological beads – which can be functionalized with proteins – into their peptide-based shell.
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With this unique setup, we provide a whole new universe of applications to the iGEM community.</p>
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Latest revision as of 02:25, 2 November 2017

EncaBcillus It´s a trap! Tooltip
Entering a Whole New Universe of Applications
Fmoc-FF is a upon pH drop. molecule, that self-assembles You can build up small spheres with it! They are called Peptidosomes. Microbes have so many powerful properties! Can molecules pass the cage to reach our microbes? That way we could enable communication between separately trapped microbes! Maybe we can even attach a function to the surface? We could build biosensors! Let's bring chemistry and biology together! out, let's build a toolbox that protein secretion easier for everybody! To find makes optimizing Do microbes survive, grow and stay insidePeptidosomes? TU Dresden iGEM team proudly presents EncaBcillus: encapsulating microbes. A novel platform for The And what about the secretion other way around? factories! Encapsulated Using Bacillus subtilis we Peptidosomes. Mission accomplished! bring life into We'll need a special vector for evaluation.