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| − | {{Heidelberg/templateus/Heading|Kevin Esvelt´s Lecture at our University}} | + | {{Heidelberg/templateus/Heading|Responsible Genetic Engineering Course in our Lab}} |
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| − | Opening science to a broad public is a major goal in iGEM. To <a href= "https://2017.igem.org/Team:Heidelberg/Engagement# Public_Survey_PP"> integrate public opinions and concerns</a> into the scientific process is increasingly important as new biological inventions could influence the humanity as a whole, the environment and our coexistence with nature. Therefore, we did not want to miss the opportunity to host <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt</a >, the inventor of PACE (phage-assisted continuous evolution) and CRISPR-based gene drives, for an open lecture at our university. Kevin Esvelt presented his work on "Gene drive evolution, localization, and restoration". This highly intriguing topic and he, being the speaker, attracted more than 300 students and researchers with various different backgrounds. The concept of gene drives already exists in nature and allows particular genes to spread through populations even if those genes are not necessarily beneficial for an organism´s fitness. Kevin Esvelt and his colleagues mimicked this naturally occurring concept using the CRISPR/Cas technology, thereby enabling genetic alterations in sexually reproducing organisms to spread throughout populations. This way, new genes can be introduced into populations, e.g. to control reproduction of apopulation under specific circumstances. Consequently, applications of gene drives include preventing the spread of pathogen carrying insects like mosquitos transmitting malaria. As gene drives are a tool to bias inheritance of genes, the potential, enormous impact of releasing gene drive carrying organisms into nature raises major bioethical concerns. Therefore, Kevin Esvelt´s is continuously perusing an open dialog with the society about benefits and potential risks of scientific technologies before they are even started to be implemented in his lab. Notably, this aim of integrating the public opinion and discussion into the scientific process from the very beginning is also a hallmark of and key criterion for <a href= "https://2017.igem.org/Team:Heidelberg/Integrated_Gold"> successful iGEM projects</a> . By giving people a voice, they also get a choice. Emerging technologies may affect countries or even our planet as a whole and the <a href="https://2017. igem.org/Team:Heidelberg/Engagement#Public_Survey_PP">broad public</a> should have a voice in which way technology should be developed and how it is to be used. Besides CRISPR-based gene drives, Kevin Esvelt is also the inventor of PACE (phage-assisted continuous evolution), the method we want to build upon in our project. We were lucky to not only host Kevin Esvelt’s lecture at the BioQuant building, but even had the opportunity to actually show him our lab (which is located in BioQuant) and PACE apparatus and discuss our iGEM project. He provided extremely helpful advice not only on how to set up PACE technically, but also on how to design corresponding experiments safely and responsibly and how to communicate our project outside the scientific community. | + | Arousing the interest of High School students for science is a major aim we pursued during our Eduction activites. Besides the <a href=# iGEM Seminar> iGEM Seminar</a> we gave at a local high school we received a request from a high school from Berlin. They were highly interested in visiting our lab for gaining some practical experience and getting insights into the research on directed evolution we perform in our lab. We hosted this high school class for a course on responsible genetic engineering in our lab. First we gave a short lecture on evolution, gene technology and introduced the theoretical background of our project to the class. We asked them to fill in our <a href= #Survey School Berlin> Survey for High School Students</a> and they answered our questions with great passion. After they have gained enough theoretical knowledge about the experiments we perform in our lab, the attended a safety instruction held by our PI Dominik Niopek. They learned how to behave in a risk group 1 laboratory like our iGEM lab, for example that everyone needs to wear a lab coat and gloves, that food and drinks are forbidden as well as more general safety and hygiene measures like how to wash one´s hands. |
| − | If you are interested in how we integrated <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt’s advice</a> into our project design, please visit our <a href="https://2017.igem.org/Team:Heidelberg/Integrated_Gold">Integrated Human Practices page</a>. We are proud of having hosted Kevin Esvelt as a speaker and guest and are thankful for his inspiring input that shaped our project from its very beginning on.
| + | <br> |
| | + | The feedback we received was althrough positive and they left our iGEM lab with new experiences and a general impression on about every day live of scientists in the field of Synthetic Biology. |
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| | {{Heidelberg/templateus/Shadebox| | | {{Heidelberg/templateus/Shadebox| |
| − | {{Heidelberg/templateus/Heading|Kevin Esvelt´s Lecture at our University}} | + | {{Heidelberg/templateus/Heading|Tobias´ Internship at the iGEM lab}} |
| | {{#tag:html| | | {{#tag:html| |
| | | | |
| − | Opening science to a broad public is a major goal in iGEM. To <a href="https:// 2017. igem.org/Team:Heidelberg/Engagement#Public_Survey_PP"> integrate public opinions and concerns</a> into the scientific process is increasingly important as new biological inventions could influence the humanity as a whole, the environment and our coexistence with nature. Therefore, we did not want to miss the opportunity to host <a href="https://2017. igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt</a>, the inventor of PACE (phage-assisted continuous evolution) and CRISPR-based gene drives, for an open lecture at our university. Kevin Esvelt presented his work on "Gene drive evolution, localization, and restoration". This highly intriguing topic and he, being the speaker, attracted more than 300 students and researchers with various different backgrounds. The concept of gene drives already exists in nature and allows particular genes to spread through populations even if those genes are not necessarily beneficial for an organism´s fitness. Kevin Esvelt and his colleagues mimicked this naturally occurring concept using the CRISPR/Cas technology, thereby enabling genetic alterations in sexually reproducing organisms to spread throughout populations. This way, new genes can be introduced into populations, e.g. to control reproduction of apopulation under specific circumstances. Consequently, applications of gene drives include preventing the spread of pathogen carrying insects like mosquitos transmitting malaria. As gene drives are a tool to bias inheritance of genes, the potential, enormous impact of releasing gene drive carrying organisms into nature raises major bioethical concerns. Therefore, Kevin Esvelt´s is continuously perusing an open dialog with the society about benefits and potential risks of scientific technologies before they are even started to be implemented in his lab. Notably, this aim of integrating the public opinion and discussion into the scientific process from the very beginning is also a hallmark of and key criterion for <a href="https://2017. igem.org/Team:Heidelberg/Integrated_Gold"> successful iGEM projects</a>. By giving people a voice, they also get a choice. Emerging technologies may affect countries or even our planet as a whole and the <a href="https://2017.igem.org/Team:Heidelberg/Engagement#Public_Survey_PP">broad public</a> should have a voice in which way technology should be developed and how it is to be used. Besides CRISPR-based gene drives, Kevin Esvelt is also the inventor of PACE (phage-assisted continuous evolution), the method we want to build upon in our project. We were lucky to not only host Kevin Esvelt’s lecture at the BioQuant building, but even had the opportunity to actually show him our lab (which is located in BioQuant) and PACE apparatus and discuss our iGEM project . He provided extremely helpful advice not only on how to set up PACE technically, but also on how to design corresponding experiments safely and responsibly and how to communicate our project outside the scientific community. | + | The High School <a href="https:// fro-ev. de"> Research Lab Ortenau</a> is a place for young scientists to get in touch with biological research and to gain wet-lab experience. We decided to closely collaborate with the High School Research lab during the 2017 iGEM season. The Research Lab Ortenau aims at arousing the student’s interest for biology. Mentoring the High School students meant great responsibility for us, and provided the opportunity to be involved even more in the synthetic biology community. We even intensified the collaboration, when Tobias Stadelmann, a high school student from the Research Lab Ortenau, asked whether it would be possible to work in our iGEM lab for a two-week internship. In the High School Research Lab Tobias is working on a project based on DNAzmes. During the time in our iGEM lab, Tobias was involved in our experiments to simplify PACE and to establish PREDCEL for directed evolution approaches. We are sure that all of us, Tobias, the High School Research Lab Ortenau, and the iGEM team gained profit from this collaboration. We are confident, that Tobias can apply the newly learned techniques to his DNazymes project and that he can transfer the know-how to other projects in the High School Research Lab Ortenau. |
| − | If you are interested in how we integrated <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt’s advice</a> into our project design, please visit our <a href="https://2017.igem.org/Team:Heidelberg/Integrated_Gold">Integrated Human Practices page</a>. We are proud of having hosted Kevin Esvelt as a speaker and guest and are thankful for his inspiring input that shaped our project from its very beginning on.
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| − | {{#tag:html|<div id="engagement"></div>}}
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| − | {{Heidelberg/templateus/Heading|Kevin Esvelt´s Lecture at our University}}
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| − | {{#tag:html|
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| − | Opening science to a broad public is a major goal in iGEM. To <a href="https://2017.igem.org/Team:Heidelberg/Engagement#Public_Survey_PP">integrate public opinions and concerns</a> into the scientific process is increasingly important as new biological inventions could influence the humanity as a whole, the environment and our coexistence with nature. Therefore, we did not want to miss the opportunity to host <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt</a>, the inventor of PACE (phage-assisted continuous evolution) and CRISPR-based gene drives, for an open lecture at our university. Kevin Esvelt presented his work on "Gene drive evolution, localization, and restoration". This highly intriguing topic and he, being the speaker, attracted more than 300 students and researchers with various different backgrounds. The concept of gene drives already exists in nature and allows particular genes to spread through populations even if those genes are not necessarily beneficial for an organism´s fitness. Kevin Esvelt and his colleagues mimicked this naturally occurring concept using the CRISPR/Cas technology, thereby enabling genetic alterations in sexually reproducing organisms to spread throughout populations. This way, new genes can be introduced into populations, e.g. to control reproduction of apopulation under specific circumstances. Consequently, applications of gene drives include preventing the spread of pathogen carrying insects like mosquitos transmitting malaria. As gene drives are a tool to bias inheritance of genes, the potential, enormous impact of releasing gene drive carrying organisms into nature raises major bioethical concerns. Therefore, Kevin Esvelt´s is continuously perusing an open dialog with the society about benefits and potential risks of scientific technologies before they are even started to be implemented in his lab. Notably, this aim of integrating the public opinion and discussion into the scientific process from the very beginning is also a hallmark of and key criterion for <a href="https://2017.igem.org/Team:Heidelberg/Integrated_Gold"> successful iGEM projects</a>. By giving people a voice, they also get a choice. Emerging technologies may affect countries or even our planet as a whole and the <a href="https://2017.igem.org/Team:Heidelberg/Engagement#Public_Survey_PP">broad public</a> should have a voice in which way technology should be developed and how it is to be used. Besides CRISPR-based gene drives, Kevin Esvelt is also the inventor of PACE (phage-assisted continuous evolution), the method we want to build upon in our project. We were lucky to not only host Kevin Esvelt’s lecture at the BioQuant building, but even had the opportunity to actually show him our lab (which is located in BioQuant) and PACE apparatus and discuss our iGEM project. He provided extremely helpful advice not only on how to set up PACE technically, but also on how to design corresponding experiments safely and responsibly and how to communicate our project outside the scientific community.
| |
| − | If you are interested in how we integrated <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt’s advice</a> into our project design, please visit our <a href="https://2017.igem.org/Team:Heidelberg/Integrated_Gold">Integrated Human Practices page</a>. We are proud of having hosted Kevin Esvelt as a speaker and guest and are thankful for his inspiring input that shaped our project from its very beginning on.
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| | + | {{#tag:html| |
| | + | {{Heidelberg/templateus/Contentsection| |
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| | {{#tag:html|<div id="engagement"></div>}} | | {{#tag:html|<div id="engagement"></div>}} |
| | {{Heidelberg/templateus/Shadebox| | | {{Heidelberg/templateus/Shadebox| |
| − | {{Heidelberg/templateus/Heading|Kevin Esvelt´s Lecture at our University}} | + | {{Heidelberg/templateus/Heading|iGEM Seminar at a local High School}} |
| | {{#tag:html| | | {{#tag:html| |
| | | | |
| − | Opening science to a broad public is a major goal in iGEM. To <a href= "https://2017.igem.org/Team:Heidelberg/Engagement# Public_Survey_PP"> integrate public opinions and concerns</a> into the scientific process is increasingly important as new biological inventions could influence the humanity as a whole, the environment and our coexistence with nature. Therefore, we did not want to miss the opportunity to host <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt</a >, the inventor of PACE (phage-assisted continuous evolution) and CRISPR-based gene drives, for an open lecture at our university. Kevin Esvelt presented his work on "Gene drive evolution, localization, and restoration". This highly intriguing topic and he, being the speaker, attracted more than 300 students and researchers with various different backgrounds. The concept of gene drives already exists in nature and allows particular genes to spread through populations even if those genes are not necessarily beneficial for an organism´s fitness. Kevin Esvelt and his colleagues mimicked this naturally occurring concept using the CRISPR/Cas technology, thereby enabling genetic alterations in sexually reproducing organisms to spread throughout populations. This way, new genes can be introduced into populations, e.g. to control reproduction of apopulation under specific circumstances. Consequently, applications of gene drives include preventing the spread of pathogen carrying insects like mosquitos transmitting malaria. As gene drives are a tool to bias inheritance of genes, the potential, enormous impact of releasing gene drive carrying organisms into nature raises major bioethical concerns. Therefore, Kevin Esvelt´s is continuously perusing an open dialog with the society about benefits and potential risks of scientific technologies before they are even started to be implemented in his lab. Notably, this aim of integrating the public opinion and discussion into the scientific process from the very beginning is also a hallmark of and key criterion for <a href= "https://2017.igem.org/Team:Heidelberg/Integrated_Gold"> successful iGEM projects</a> . By giving people a voice, they also get a choice. Emerging technologies may affect countries or even our planet as a whole and the <a href="https://2017. igem.org/Team:Heidelberg/Engagement#Public_Survey_PP">broad public</a> should have a voice in which way technology should be developed and how it is to be used. Besides CRISPR-based gene drives, Kevin Esvelt is also the inventor of PACE (phage-assisted continuous evolution), the method we want to build upon in our project. We were lucky to not only host Kevin Esvelt’s lecture at the BioQuant building, but even had the opportunity to actually show him our lab (which is located in BioQuant) and PACE apparatus and discuss our iGEM project. He provided extremely helpful advice not only on how to set up PACE technically, but also on how to design corresponding experiments safely and responsibly and how to communicate our project outside the scientific community. | + | Arousing the interest of High School students for science is a major aim we pursued during our Eduction activites. Besides the <a href=# iGEM Seminar> iGEM Seminar</a> we gave at a local high school we received a request from a high school from Berlin. They were highly interested in visiting our lab for gaining some practical experience and getting insights into the research on directed evolution we perform in our lab. We hosted this high school class for a course on responsible genetic engineering in our lab. First we gave a short lecture on evolution, gene technology and introduced the theoretical background of our project to the class. We asked them to fill in our <a href= #Survey School Berlin> Survey for High School Students</a> and they answered our questions with great passion. After they have gained enough theoretical knowledge about the experiments we perform in our lab, the attended a safety instruction held by our PI Dominik Niopek. They learned how to behave in a risk group 1 laboratory like our iGEM lab, for example that everyone needs to wear a lab coat and gloves, that food and drinks are forbidden as well as more general safety and hygiene measures like how to wash one´s hands. |
| − | If you are interested in how we integrated <a href="https://2017.igem.org/Team:Heidelberg/Interviews#Esvelt_expert_PP">Kevin Esvelt’s advice</a> into our project design, please visit our <a href="https://2017.igem.org/Team:Heidelberg/Integrated_Gold">Integrated Human Practices page</a>. We are proud of having hosted Kevin Esvelt as a speaker and guest and are thankful for his inspiring input that shaped our project from its very beginning on.
| + | <br> |
| − | }}
| + | The feedback we received was althrough positive and they left our iGEM lab with new experiences and a general impression on about every day live of scientists in the field of Synthetic Biology. |
| | + | |
| | }} | | }} |
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