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                 We apply deep learning models to harness the complex sequence to function relation in proteins. |Explore
 
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Revision as of 13:44, 1 November 2017


AiGEM
Artificial intelligence for Genetic Evolution Mimicking
abstract
[[:Template:Https://static.igem.org/mediawiki/2017/b/b7/T--Heidelberg--2017 DeeProtein LOGO.jpg]]
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GAIA

By interfacing our trained models with a genetic algorithm we developed an in silico evolution tool.

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SafteyNet

To perform self-checks, and prevent misuse of directed evolution techniques, we developed SafetyNet a sensitive tool for the detection of harmful traits in sequences.

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Validation

Deploying GAIA, we fully in silico evolved a beta lactamase and reprogrammed the E. Coli beta glucuronidase towards beta galactosidase function.

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MAWS 2.0

Description