Team:Paris Bettencourt/RNA
RNA Organelle
New Order
In synthetic biology, we are often introducing new systems to bacteria that are not designed to use the new pathway. The synthetic pathway will produce new and exotic enzymes and proteins for the host bacteria which will not have necessary internal environment to organise these macromolecular products, this could be detrimental to the system or even the host bacteria itself. So we are creating a standardized microenvironment in the cell wherein the pathway components are trapped and perform in a predictable way
RNA is a light cost nucleotide material in the cell,
We aim to recreate RNA agglomerations as formed
in mammalian cells with triple repeat disorders,
which show liquid phase separation, forming a
organelle-like vesicle, where local concentrations of
enzymes can be created.
Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
bettencourt.igem2017@gmail.com
bettencourt.igem2017@gmail.com 
