Difference between revisions of "Team:Edinburgh OG"

Line 1: Line 1:
<html>
 
 
{{Edinburgh_OG}}
 
{{Edinburgh_OG}}
 +
<html>
 +
  
 
   <!--
 
   <!--

Revision as of 21:49, 21 May 2017

PhagED: a molecular toolkit to re-sensitise ESKAPE pathogens

Antibiotic revolution: a molecular toolkit to re-sensitise
Methycillin resistant S.aureus (MRSA) Vancomycin resistant S.aureus (VRSA) Klebsiella pneumoniae Pseudomonas aeruginosa Enterococcus faecalis/faecium Acinetobacter baumanii

Modular molecular toolkit for re-sensitisation of antibiotic-resistant pathogens using CRISPR delivered by a two-phage system.

Read more

ABOUT PhagED

The world is currently facing a future where antibiotics no longer work and basic infections cannot be treated. Many of the most dangerous diseases which are not treatable arise from the hospital environment. This is because the bacteria have had lots of exposure to antibiotics, allowing them time to evolve genes which can help them survive in the presence of these drugs. We therefore want to tackle this problem of the 'super bugs' found in our hospitals, otherwise known as the ESKAPE pathogens.

We will do this by developing a spray which will contain modified phages. When that phage enters the cell, CRISPR-Cas system will cut up the genes which are giving the bacteria resistance to antibiotics. We then add another phage to ensure this system is maintainable.

By using this spray, we hope to re-sensitise these dangerous antibiotic resistant bacteria to the drugs again, allowing conventional antiobiotics to work. This would mean we would no longer need to develop costly new antibiotics, and avoid the coming doom of a world where a UTI is a death sentence. Neat eh?!

TAKE A CLOSER LOOK

Aliquam lobortis. Maecenas vestibulum mollis diam. Pellentesque auctor neque nec urna. Nulla sit amet est. Aenean posuere
tortor sed cursus feugiat, nunc augue blandit nunc, eu sollicitudin urna dolor sagittis lacus.

Project

Get to know PhagED better.

Parts

Blocks of DNA that we've used.

Safety

Safety always comes first.

Human Practices

How PhaED fits into the context.

Meet The Team

Filippo Abbondanza

MSc Synthetic Biology & Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore

Erin Corbett

MSc Synthetic Biology & Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Rikki He

MSc Biochemistry

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Ti He

MSc Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Lydia Mapstone

MSc Synthetic Biology & Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore

Yuri Matsueda

MSc Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Anton Puzorjov

MSc Bioinformatics

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Yating Wang

MSc Drug Discovery & Translational Biology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .

Owen Yeung

MSc Synthetic Biology & Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore

DO YOU WANT TO HELP US TURN IT INTO REALITY?

Feel free to drop us a line or two and we'll be in touch soon!

Contact