Difference between revisions of "Team:CPU CHINA"

Revision as of 15:12, 1 November 2017

Our HEAD-Treg

Description

Rheumatoid arthritis (RA) is a serious chronic, inflammatory and systemic autoimmune disease.
It is of great essence to develop a novel cell-targeted therapy for RA because there is no radical cure for RA for the time being.
To solve the problems existing in the current treatment of RA, we design and build a brand new immunotherapy.
FOXP3+ regulatory T cells(Tregs), which can suppress and regulate immune reactions, are modified
utilizing a lentiviral vector system to express a chimeric antigen receptor(CAR) targeting inflammatory cells associated with RA.
Meanwhile, we insert the Syn-Notch receptor to activate the functional stability pathway of Tregs in the inflammatory environment, which enables them to play their role of immunosuppression in lesions more efficiently and more stably.
These two redirections of the two different but interrelated systems on Tregs ensure this novel therapy a promising anti-RA effect.

@@ Line 25: / Line 25: @@
      <div class="body-container">
-             <center class="pagee pagee0" style="position:relative!important;">
+             <center class="pagee pagee0" id="dyk">
              	<p><br>&nbsp;<br></p>
              	<p><br>&nbsp;<br></p>
@@ Line 283: / Line 283: @@
 <script type="text/javascript">
 !function(e){var t={sectionContainer:"section",easing:"ease",animationTime:1e3,pagination:true,updateURL:false,keyboard:true,beforeMove:null,afterMove:null,loop:true,responsiveFallback:false,direction:"vertical"};e.fn.swipeEvents=function(){return this.each(function(){function i(e){var i=e.originalEvent.touches;if(i&&i.length){t=i[0].pageX;n=i[0].pageY;r.bind("touchmove",s)}}function s(e){var i=e.originalEvent.touches;if(i&&i.length){var o=t-i[0].pageX;var u=n-i[0].pageY;if(o>=50){r.trigger("swipeLeft")}if(o<=-50){r.trigger("swipeRight")}if(u>=50){r.trigger("swipeUp")}if(u<=-50){r.trigger("swipeDown")}if(Math.abs(o)>=50||Math.abs(u)>=50){r.unbind("touchmove",s)}}}var t,n,r=e(this);r.bind("touchstart",i)})};e.fn.onepage_scroll=function(n){function o(){var t=false;var n=typeof r.responsiveFallback;if(n=="number"){t=e(window).width()<r.responsiveFallback}if(n=="boolean"){t=r.responsiveFallback}if(n=="function"){valFunction=r.responsiveFallback();t=valFunction;typeOFv=typeof t;if(typeOFv=="number"){t=e(window).width()<valFunction}}if(t){e("body").addClass("disabled-onepage-scroll");e(document).unbind("mousewheel DOMMouseScroll MozMousePixelScroll");i.swipeEvents().unbind("swipeDown swipeUp")}else{if(e("body").hasClass("disabled-onepage-scroll")){e("body").removeClass("disabled-onepage-scroll");e("html, body, .wrapper").animate({scrollTop:0},"fast")}i.swipeEvents().bind("swipeDown",function(t){if(!e("body").hasClass("disabled-onepage-scroll"))t.preventDefault();i.moveUp()}).bind("swipeUp",function(t){if(!e("body").hasClass("disabled-onepage-scroll"))t.preventDefault();i.moveDown()});e(document).bind("mousewheel DOMMouseScroll MozMousePixelScroll",function(e){e.preventDefault();var t=e.originalEvent.wheelDelta||-e.originalEvent.detail;u(e,t)})}}function u(e,t){deltaOfInterest=t;var n=(new Date).getTime();if(n-lastAnimation<quietPeriod+r.animationTime){e.preventDefault();return}if(deltaOfInterest<0){i.moveDown()}else{i.moveUp()}lastAnimation=n}var r=e.extend({},t,n),i=e(this),s=e(r.sectionContainer);total=s.length,status="off",topPos=0,leftPos=0,lastAnimation=0,quietPeriod=500,paginationList="";e.fn.transformPage=function(t,n,r){if(typeof t.beforeMove=="function")t.beforeMove(r);e(this).css({"-webkit-transform":t.direction=="horizontal"?"translate3d("+n+"%, 0, 0)":"translate3d(0, "+n+"%, 0)","-webkit-transition":"all "+t.animationTime+"ms "+t.easing,"-moz-transform":t.direction=="horizontal"?"translate3d("+n+"%, 0, 0)":"translate3d(0, "+n+"%, 0)","-moz-transition":"all "+t.animationTime+"ms "+t.easing,"-ms-transform":t.direction=="horizontal"?"translate3d("+n+"%, 0, 0)":"translate3d(0, "+n+"%, 0)","-ms-transition":"all "+t.animationTime+"ms "+t.easing,transform:t.direction=="horizontal"?"translate3d("+n+"%, 0, 0)":"translate3d(0, "+n+"%, 0)",transition:"all "+t.animationTime+"ms "+t.easing});e(this).one("webkitTransitionEnd otransitionend oTransitionEnd msTransitionEnd transitionend",function(e){if(typeof t.afterMove=="function")t.afterMove(r)})};e.fn.moveDown=function(){var t=e(this);index=e(r.sectionContainer+".active").data("index");current=e(r.sectionContainer+"[data-index='"+index+"']");next=e(r.sectionContainer+"[data-index='"+(index+1)+"']");if(next.length<1){if(r.loop==true){pos=0;next=e(r.sectionContainer+"[data-index='1']")}else{return}}else{pos=index*100*-1}if(typeof r.beforeMove=="function")r.beforeMove(next.data("index"));current.removeClass("active");next.addClass("active");if(r.pagination==true){e(".onepage-pagination li a"+"[data-index='"+index+"']").removeClass("active");e(".onepage-pagination li a"+"[data-index='"+next.data("index")+"']").addClass("active")}e("body")[0].className=e("body")[0].className.replace(/\bviewing-page-\d.*?\b/g,"");e("body").addClass("viewing-page-"+next.data("index"));if(history.replaceState&&r.updateURL==true){var n=window.location.href.substr(0,window.location.href.indexOf("#"))+"#"+(index+1);history.pushState({},document.title,n)}t.transformPage(r,pos,next.data("index"))};e.fn.moveUp=function(){var t=e(this);index=e(r.sectionContainer+".active").data("index");current=e(r.sectionContainer+"[data-index='"+index+"']");next=e(r.sectionContainer+"[data-index='"+(index-1)+"']");if(next.length<1){if(r.loop==true){pos=(total-1)*100*-1;next=e(r.sectionContainer+"[data-index='"+total+"']")}else{return}}else{pos=(next.data("index")-1)*100*-1}if(typeof r.beforeMove=="function")r.beforeMove(next.data("index"));current.removeClass("active");next.addClass("active");if(r.pagination==true){e(".onepage-pagination li a"+"[data-index='"+index+"']").removeClass("active");e(".onepage-pagination li a"+"[data-index='"+next.data("index")+"']").addClass("active")}e("body")[0].className=e("body")[0].className.replace(/\bviewing-page-\d.*?\b/g,"");e("body").addClass("viewing-page-"+next.data("index"));if(history.replaceState&&r.updateURL==true){var n=window.location.href.substr(0,window.location.href.indexOf("#"))+"#"+(index-1);history.pushState({},document.title,n)}t.transformPage(r,pos,next.data("index"))};e.fn.moveTo=function(t){current=e(r.sectionContainer+".active");next=e(r.sectionContainer+"[data-index='"+t+"']");if(next.length>0){if(typeof r.beforeMove=="function")r.beforeMove(next.data("index"));current.removeClass("active");next.addClass("active");e(".onepage-pagination li a"+".active").removeClass("active");e(".onepage-pagination li a"+"[data-index='"+t+"']").addClass("active");e("body")[0].className=e("body")[0].className.replace(/\bviewing-page-\d.*?\b/g,"");e("body").addClass("viewing-page-"+next.data("index"));pos=(t-1)*100*-1;if(history.replaceState&&r.updateURL==true){var n=window.location.href.substr(0,window.location.href.indexOf("#"))+"#"+(t-1);history.pushState({},document.title,n)}i.transformPage(r,pos,t)}};i.addClass("onepage-wrapper").css("position","relative");e.each(s,function(t){e(this).css({position:"absolute",top:topPos+"%"}).addClass("section").attr("data-index",t+1);e(this).css({position:"absolute",left:r.direction=="horizontal"?leftPos+"%":0,top:r.direction=="vertical"||r.direction!="horizontal"?topPos+"%":0});if(r.direction=="horizontal")leftPos=leftPos+100;else topPos=topPos+100;if(r.pagination==true){paginationList+="<li><a data-index='"+(t+1)+"' href='#"+(t+1)+"'></a></li>"}});i.swipeEvents().bind("swipeDown",function(t){if(!e("body").hasClass("disabled-onepage-scroll"))t.preventDefault();i.moveUp()}).bind("swipeUp",function(t){if(!e("body").hasClass("disabled-onepage-scroll"))t.preventDefault();i.moveDown()});if(r.pagination==true){if(e("ul.onepage-pagination").length<1)e("<ul class='onepage-pagination'></ul>").prependTo("body");if(r.direction=="horizontal"){posLeft=i.find(".onepage-pagination").width()/2*-1;i.find(".onepage-pagination").css("margin-left",posLeft)}else{posTop=i.find(".onepage-pagination").height()/2*-1;i.find(".onepage-pagination").css("margin-top",posTop)}e("ul.onepage-pagination").html(paginationList)}if(window.location.hash!=""&&window.location.hash!="#1"){init_index=window.location.hash.replace("#","");if(parseInt(init_index)<=total&&parseInt(init_index)>0){e(r.sectionContainer+"[data-index='"+init_index+"']").addClass("active");e("body").addClass("viewing-page-"+init_index);if(r.pagination==true)e(".onepage-pagination li a"+"[data-index='"+init_index+"']").addClass("active");next=e(r.sectionContainer+"[data-index='"+init_index+"']");if(next){next.addClass("active");if(r.pagination==true)e(".onepage-pagination li a"+"[data-index='"+init_index+"']").addClass("active");e("body")[0].className=e("body")[0].className.replace(/\bviewing-page-\d.*?\b/g,"");e("body").addClass("viewing-page-"+next.data("index"));if(history.replaceState&&r.updateURL==true){var a=window.location.href.substr(0,window.location.href.indexOf("#"))+"#"+init_index;history.pushState({},document.title,a)}}pos=(init_index-1)*100*-1;i.transformPage(r,pos,init_index)}else{e(r.sectionContainer+"[data-index='1']").addClass("active");e("body").addClass("viewing-page-1");if(r.pagination==true)e(".onepage-pagination li a"+"[data-index='1']").addClass("active")}}else{e(r.sectionContainer+"[data-index='1']").addClass("active");e("body").addClass("viewing-page-1");if(r.pagination==true)e(".onepage-pagination li a"+"[data-index='1']").addClass("active")}if(r.pagination==true){e(".onepage-pagination li a").click(function(){var t=e(this).data("index");i.moveTo(t)})}e(document).bind("mousewheel DOMMouseScroll MozMousePixelScroll",function(t){t.preventDefault();var n=t.originalEvent.wheelDelta||-t.originalEvent.detail;if(!e("body").hasClass("disabled-onepage-scroll"))u(t,n)});if(r.responsiveFallback!=false){e(window).resize(function(){o()});o()}if(r.keyboard==true){e(document).keydown(function(t){var n=t.target.tagName.toLowerCase();if(!e("body").hasClass("disabled-onepage-scroll")){switch(t.which){case 38:if(n!="input"&&n!="textarea")i.moveUp();break;case 40:if(n!="input"&&n!="textarea")i.moveDown();break;case 33:if(n!="input"&&n!="textarea")i.moveUp();break;case 34:if(n!="input"&&n!="textarea")i.moveDown();break;case 36:i.moveTo(1);break;case 35:i.moveTo(total);break;default:return}}})}return false}}(window.jQuery)
+</script>
+<script>
+document.getElementById('dyk').style.position="relative!important;";
 </script>
 </html>