Difference between revisions of "Team:Edinburgh OG"

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{{Edinburgh_OG}}
 
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  <!--
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    <div class="container">
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      <div class="row">
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        <div class="col-md-12 text-center">
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          <div class="block wow fadeInUp" data-wow-delay=".3s">
  
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<div class="column full_size" >
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            <!-- Slider -->
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<img src="https://static.igem.org/mediawiki/2017/1/17/T--Edinburgh_OG--NicLogo.jpg">
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            <section class="cd-intro">
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</div>
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              <h1 class="wow fadeInUp animated cd-headline slide" data-wow-delay=".4s">
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                                <span>Antibiotic revolution: a molecular toolkit to re-sensitise </span><br>
 +
                                <span class="cd-words-wrapper">
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                                    <b class="is-visible">Methycillin resistant S.aureus (MRSA)</b>
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                                    <b>Vancomycin resistant S.aureus (VRSA)</b>
 +
                                    <b>Klebsiella pneumoniae</b>
 +
                                    <b>Pseudomonas aeruginosa</b>
 +
                                    <b>Enterococcus faecalis/faecium</b>
 +
                                    <b>Acinetobacter baumanii</b>
 +
                                </span>
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                                </h1>
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            </section>
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            <!-- cd-intro -->
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            <!-- /.slider -->
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            <h2 class="wow fadeInUp animated" data-wow-delay=".6s">
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                                    Modular molecular toolkit for re-sensitisation of antibiotic-resistant pathogens using CRISPR delivered by a two-phage system.
 +
                                </h2>
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            <a class="btn-lines dark light wow fadeInUp animated smooth-scroll btn btn-default btn-green" data-wow-delay=".9s" href="#works" data-section="#about">Read more</a>
  
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          </div>
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        </div>
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      </div>
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    </div>
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  </section>
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  <!--/#main-slider-->
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  <!--
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  <section id="about">
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    <div class="container">
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      <div class="row">
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        <div class="col-md-6 col-sm-6">
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          <div class="block wow fadeInLeft" data-wow-delay=".3s" data-wow-duration="500ms">
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            <h2>
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                                ABOUT PhagED
 +
                                </h2>
 +
            <p>
 +
              The world is currently facing a future where antibiotics no longer work and basic infections cannot be treated. Many of the most dangerous diseases which are not treatable arise from the hospital environment. This is because the bacteria have had lots
 +
              of exposure to antibiotics, allowing them time to evolve genes which can help them survive in the presence of these drugs. We therefore want to tackle this problem of the 'super bugs' found in our hospitals, otherwise known as the ESKAPE
 +
              pathogens.
 +
            </p>
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            <p>
 +
              We will do this by developing a spray which will contain modified phages. When that phage enters the cell, CRISPR-Cas system will cut up the genes which are giving the bacteria resistance to antibiotics. We then add another phage to ensure this system
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              is maintainable.
 +
            </p>
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            <p>
 +
              By using this spray, we hope to re-sensitise these dangerous antibiotic resistant bacteria to the drugs again, allowing conventional antiobiotics to work. This would mean we would no longer need to develop costly new antibiotics, and avoid the coming
 +
              doom of a world where a UTI is a death sentence. Neat eh?!
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            </p>
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          </div>
  
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        </div>
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        <div class="col-md-6 col-sm-6">
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          <div class="block wow fadeInRight" data-wow-delay=".3s" data-wow-duration="500ms">
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            <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/about/about.jpg" alt="">
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          </div>
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        </div>
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      </div>
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    </div>
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  </section>
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  <!-- /#about -->
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  <!--
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            Portfolio Section Start
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  <section id="works" class="works">
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    <div class="container">
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      <div class="row">
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        <div class="col-sm-8 col-xs-12 col-sm-offset-2">
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      <div class="section-heading">
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        <h1 class="title wow fadeInDown" data-wow-delay=".3s">TAKE A CLOSER LOOK</h1>
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        <p class="wow fadeInDown" data-wow-delay=".5s">
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          Aliquam lobortis. Maecenas vestibulum mollis diam. Pellentesque auctor neque nec urna. Nulla sit amet est. Aenean posuere <br> tortor sed cursus feugiat, nunc augue blandit nunc, eu sollicitudin urna dolor sagittis lacus.
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        </p>
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      </div>
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      <div class="row">
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        <div class="col-sm-6 col-xs-12">
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          <figure class="wow fadeInLeft animated portfolio-item" data-wow-duration="500ms" data-wow-delay="0ms">
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            <div class="img-wrapper">
 +
              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-1.jpg" class="img-responsive" alt="this is a title">
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              <div class="overlay">
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                <div class="buttons">
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                  <a rel="gallery" class="fancybox" href="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-1.jpg">Demo</a>
 +
                  <a target="_blank" href="single-portfolio.html">Details</a>
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                </div>
 +
              </div>
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            </div>
 +
            <figcaption>
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              <h4>
 +
                                <a href="#">
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                                    Project
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                                </a>
 +
                                </h4>
 +
              <p>
 +
                Get to know PhagED better.
 +
              </p>
 +
            </figcaption>
 +
          </figure>
 +
        </div>
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        <div class="col-sm-6 col-xs-12">
 +
          <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="300ms">
 +
            <div class="img-wrapper">
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              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-2.jpg" class="img-responsive" alt="this is a title">
 +
              <div class="overlay">
 +
                <div class="buttons">
 +
                  <a rel="gallery" class="fancybox" href="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-2.jpg">Demo</a>
 +
                  <a target="_blank" href="single-portfolio.html">Details</a>
 +
                </div>
 +
              </div>
 +
            </div>
 +
            <figcaption>
 +
              <h4>
 +
                                <a href="#">
 +
                                    Parts
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                                </a>
 +
                                </h4>
 +
              <p>
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                Blocks of DNA that we've used.
 +
              </p>
 +
            </figcaption>
 +
          </figure>
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        </div>
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        <div class="col-sm-6 col-xs-12">
 +
          <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="300ms">
 +
            <div class="img-wrapper">
 +
              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-3.jpg" class="img-responsive" alt="">
 +
              <div class="overlay">
 +
                <div class="buttons">
 +
                  <a rel="gallery" class="fancybox" href="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-3.jpg">Demo</a>
 +
                  <a target="_blank" href="single-portfolio.html">Details</a>
 +
                </div>
 +
              </div>
 +
            </div>
 +
            <figcaption>
 +
              <h4>
 +
                                <a href="#">
 +
                                    Safety
 +
                                </a>
 +
                                </h4>
 +
              <p>
 +
                Safety always comes first.
 +
              </p>
 +
            </figcaption>
 +
          </figure>
 +
        </div>
 +
        <div class="col-sm-6 col-xs-12">
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          <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="600ms">
 +
            <div class="img-wrapper">
 +
              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-4.jpg" class="img-responsive" alt="">
 +
              <div class="overlay">
 +
                <div class="buttons">
 +
                  <a rel="gallery" class="fancybox" href="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/portfolio/item-4.jpg">Demo</a>
 +
                  <a target="_blank" href="single-portfolio.html">Details</a>
 +
                </div>
 +
              </div>
 +
            </div>
 +
            <figcaption>
 +
              <h4>
 +
                                <a href="#">
 +
                                    Human Practices
 +
                                </a>
 +
                                </h4>
 +
              <p>
 +
                How PhaED fits into the context.
 +
              </p>
 +
            </figcaption>
 +
          </figure>
 +
        </div>
  
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<div class="column full_size" >
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      </div>
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<h1> Welcome to iGEM 2017! </h1>
+
    </div>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
+
  </div>
−
<img src="https://static.igem.org/mediawiki/2017/b/bd/T--Edinburgh_OG--Edinburgh_OG_Profile_Pic.jpg">
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</div>  
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<div class="clear"></div>
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<div class="column half_size" >
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−
<h5>Before you start: </h5>
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<p> Please read the following pages:</p>
+
−
<ul>
+
−
<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
+
−
<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
+
−
<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
+
−
</ul>
+
 
</div>
 
</div>
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  </section>
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  <!-- #works -->
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  <section id="feature" style="display:none">
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    <div class="container">
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      <div class="section-heading">
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        <h1 class="title wow fadeInDown" data-wow-delay=".3s">Offer From Me</h1>
 +
        <p class="wow fadeInDown" data-wow-delay=".5s">
 +
          Lorem ipsum dolor sit amet, consectetur adipisicing elit. Sed,<br> quasi dolores numquam dolor vero ex, tempora commodi repellendus quod laborum.
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        </p>
 +
      </div>
 +
      <div class="row">
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        <div class="col-md-4 col-lg-4 col-xs-12">
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          <div class="media wow fadeInUp animated" data-wow-duration="500ms" data-wow-delay="300ms">
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            <div class="media-left">
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              <div class="icon">
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                <i class="ion-ios-flask-outline"></i>
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              </div>
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            </div>
 +
            <div class="media-body">
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              <h4 class="media-heading">Media heading</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
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            </div>
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          </div>
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        </div>
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        <div class="col-md-4 col-lg-4 col-xs-12">
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          <div class="media wow fadeInDown animated" data-wow-duration="500ms" data-wow-delay="600ms">
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            <div class="media-left">
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              <div class="icon">
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                <i class="ion-ios-lightbulb-outline"></i>
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              </div>
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            </div>
 +
            <div class="media-body">
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              <h4 class="media-heading">Well documented.</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
 +
            </div>
 +
          </div>
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        </div>
 +
        <div class="col-md-4 col-lg-4 col-xs-12">
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          <div class="media wow fadeInDown animated" data-wow-duration="500ms" data-wow-delay="900ms">
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            <div class="media-left">
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              <div class="icon">
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                <i class="ion-ios-lightbulb-outline"></i>
 +
              </div>
 +
            </div>
 +
            <div class="media-body">
 +
              <h4 class="media-heading">Well documented.</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
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            </div>
 +
          </div>
 +
        </div>
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        <div class="col-md-4 col-lg-4 col-xs-12">
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          <div class="media wow fadeInDown animated" data-wow-duration="500ms" data-wow-delay="1200ms">
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            <div class="media-left">
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              <div class="icon">
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                <i class="ion-ios-americanfootball-outline"></i>
 +
              </div>
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            </div>
 +
            <div class="media-body">
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              <h4 class="media-heading">Free updates</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
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            </div>
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          </div>
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        </div>
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        <div class="col-md-4 col-lg-4 col-xs-12">
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          <div class="media wow fadeInDown animated" data-wow-duration="500ms" data-wow-delay="1500ms">
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            <div class="media-left">
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              <div class="icon">
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                <i class="ion-ios-keypad-outline"></i>
 +
              </div>
 +
            </div>
 +
            <div class="media-body">
 +
              <h4 class="media-heading">Solid Support</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
 +
            </div>
 +
          </div>
 +
        </div>
 +
        <div class="col-md-4 col-lg-4 col-xs-12">
 +
          <div class="media wow fadeInDown animated" data-wow-duration="500ms" data-wow-delay="1800ms">
 +
            <div class="media-left">
 +
              <div class="icon">
 +
                <i class="ion-ios-barcode-outline"></i>
 +
              </div>
 +
            </div>
 +
            <div class="media-body">
 +
              <h4 class="media-heading">Simple Installation</h4>
 +
              <p>Lorem ipsum dolor sit amet, consectetur adipisicing elit. Voluptatum, sint.</p>
 +
            </div>
 +
          </div>
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        </div>
 +
      </div>
 +
    </div>
 +
  </section>
 +
  <!--
 +
  ==================================================
 +
      Team Section Start
 +
  ================================================== -->
 +
  <section id="team">
 +
    <div class="container">
 +
      <div class="row">
 +
        <h2 class="subtitle text-center">Meet The Team</h2>
 +
        <div class="col-md-3">
 +
          <div class="team-member wow fadeInLeft" data-wow-duration="500ms" data-wow-delay=".3s">
 +
            <div class="team-img">
 +
              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/team/filippo.JPG" class="team-pic" alt="">
 +
            </div>
 +
            <h3 class="team_name">Filippo Abbondanza</h3>
 +
            <p class="team_designation">MSc Synthetic Biology & Biotechnology</p>
 +
            <p class="team_text">Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore </p>
 +
            <p class="social-icons">
 +
              <a href="#" class="facebook" target="_blank"><i class="ion-social-facebook-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-twitter-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-linkedin-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-googleplus-outline"></i></a>
 +
            </p>
 +
          </div>
 +
        </div>
 +
        <div class="col-md-3">
 +
          <div class="team-member wow fadeInLeft" data-wow-duration="500ms" data-wow-delay=".5s">
 +
            <div class="team-img">
 +
              <img src="https://rawgit.com/Macbit/Edinburgh_OG_iGEM17/master/images/team/erin.JPG" class="team-pic" alt="">
 +
            </div>
 +
            <h3 class="team_name">Erin Corbett</h3>
 +
            <p class="team_designation">MSc Synthetic Biology & Biotechnology</p>
 +
            <p class="team_text">Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore .</p>
 +
            <p class="social-icons">
 +
              <a href="#" class="facebook" target="_blank"><i class="ion-social-facebook-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-twitter-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-linkedin-outline"></i></a>
 +
              <a href="#" target="_blank"><i class="ion-social-googleplus-outline"></i></a>
 +
            </p>
 +
          </div>
 +
        </div>
 +
        <div class="col-md-3">
 +
          <div class="team-member wow fadeInLeft" data-wow-duration="500ms" data-wow-delay=".7s">
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            <h3 class="team_name">Rikki He</h3>
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Revision as of 21:48, 21 May 2017

PhagED: a molecular toolkit to re-sensitise ESKAPE pathogens 

 <section id="hero-area">

           <section class="cd-intro">

Antibiotic revolution: a molecular toolkit to re-sensitise
Methycillin resistant S.aureus (MRSA) Vancomycin resistant S.aureus (VRSA) Klebsiella pneumoniae Pseudomonas aeruginosa Enterococcus faecalis/faecium Acinetobacter baumanii 

           </section>

Modular molecular toolkit for re-sensitisation of antibiotic-resistant pathogens using CRISPR delivered by a two-phage system.

           <a class="btn-lines dark light wow fadeInUp animated smooth-scroll btn btn-default btn-green" data-wow-delay=".9s" href="#works" data-section="#about">Read more</a>

 </section>
 <section id="about">

ABOUT PhagED

The world is currently facing a future where antibiotics no longer work and basic infections cannot be treated. Many of the most dangerous diseases which are not treatable arise from the hospital environment. This is because the bacteria have had lots of exposure to antibiotics, allowing them time to evolve genes which can help them survive in the presence of these drugs. We therefore want to tackle this problem of the 'super bugs' found in our hospitals, otherwise known as the ESKAPE pathogens.

We will do this by developing a spray which will contain modified phages. When that phage enters the cell, CRISPR-Cas system will cut up the genes which are giving the bacteria resistance to antibiotics. We then add another phage to ensure this system is maintainable.

By using this spray, we hope to re-sensitise these dangerous antibiotic resistant bacteria to the drugs again, allowing conventional antiobiotics to work. This would mean we would no longer need to develop costly new antibiotics, and avoid the coming doom of a world where a UTI is a death sentence. Neat eh?! 

           <img src="about.jpg" alt="">

 </section>
 <section id="works" class="works">

TAKE A CLOSER LOOK

Aliquam lobortis. Maecenas vestibulum mollis diam. Pellentesque auctor neque nec urna. Nulla sit amet est. Aenean posuere
tortor sed cursus feugiat, nunc augue blandit nunc, eu sollicitudin urna dolor sagittis lacus. 

         <figure class="wow fadeInLeft animated portfolio-item" data-wow-duration="500ms" data-wow-delay="0ms">

             <img src="item-1.jpg" class="img-responsive" alt="this is a title">

                 <a rel="gallery" class="fancybox" href="item-1.jpg">Demo</a>
                 <a target="_blank" href="single-portfolio.html">Details</a>

           <figcaption>

<a href="#"> Project </a>

Get to know PhagED better. 

           </figcaption>
         </figure>

         <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="300ms">

             <img src="item-2.jpg" class="img-responsive" alt="this is a title">

                 <a rel="gallery" class="fancybox" href="item-2.jpg">Demo</a>
                 <a target="_blank" href="single-portfolio.html">Details</a>

           <figcaption>

<a href="#"> Parts </a>

Blocks of DNA that we've used. 

           </figcaption>
         </figure>

         <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="300ms">

             <img src="item-3.jpg" class="img-responsive" alt="">

                 <a rel="gallery" class="fancybox" href="item-3.jpg">Demo</a>
                 <a target="_blank" href="single-portfolio.html">Details</a>

           <figcaption>

<a href="#"> Safety </a>

Safety always comes first. 

           </figcaption>
         </figure>

         <figure class="wow fadeInLeft animated" data-wow-duration="500ms" data-wow-delay="600ms">

             <img src="item-4.jpg" class="img-responsive" alt="">

                 <a rel="gallery" class="fancybox" href="item-4.jpg">Demo</a>
                 <a target="_blank" href="single-portfolio.html">Details</a>

           <figcaption>

<a href="#"> Human Practices </a>

How PhaED fits into the context. 

           </figcaption>
         </figure>

 </section>
 <section id="feature" style="display:none">

Offer From Me

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quasi dolores numquam dolor vero ex, tempora commodi repellendus quod laborum.

Media heading

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Well documented.

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Well documented.

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Free updates

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Solid Support

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Simple Installation

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 </section>
 <section id="team">

Meet The Team

             <img src="filippo.JPG" class="team-pic" alt="">

Filippo Abbondanza

MSc Synthetic Biology & Biotechnology

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             <img src="erin.JPG" class="team-pic" alt="">

Erin Corbett

MSc Synthetic Biology & Biotechnology

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             <img src="rikki.JPG" class="team-pic" alt="">

Rikki He

MSc Biochemistry

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             <img src="ti.JPG" class="team-pic" alt="">

Ti He

MSc Biotechnology

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               <img src="lydia.JPG" class="team-pic" alt="">

Lydia Mapstone

MSc Synthetic Biology & Biotechnology

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore 

               <img src="yuri.JPG" class="team-pic" alt="">

Yuri Matsueda

MSc Biotechnology

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Anton Puzorjov

MSc Bioinformatics

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Yating Wang

MSc Drug Discovery & Translational Biology

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Owen Yeung

MSc Synthetic Biology & Biotechnology

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